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| 1 | 柴达木盆地大红沟剖面新生代地层磁组构特征及构造意义显示文摘研究表明柴达木盆地新生代沉积物磁化率各向异性能够有效地记录印度-欧亚板块碰撞的应力场方向,然而过去对该盆地磁组构研究主要集中在始新世下干柴沟组和中新世下油砂山组,因此不能有效界定应力场方向发生变化的年代。本文对柴达木盆地北缘大红沟剖面沉积岩进行了详细的磁组构分析,获得了新生代较高分辨率(平均6~10m)的磁化率各向异性数据。结果表明,下干柴沟组、上干柴沟组、下油砂山组和上油砂山组及狮子沟组磁面理发育较为明显,磁化率椭球体呈压扁状,具有较强的压扁效应;而路乐河组磁线理发育更为明显,可能记录了较强的构造作用力。路乐河组和下干柴沟组磁组构指示构造应力的方向为近南北向;上干柴沟组和下油砂山组磁组构指示应力的方向为东北-西南向。因此,柴达木盆地由南北向挤压转变为东北-西南向挤压发生在始新世下干柴沟组和渐新世上干柴沟组之间,指示青藏高原北部应力场发生了变化。我们将青藏高原北部应力场的转变归因于阿尔金断裂的左旋走滑,而中晚中新世应力的进一步加强可能与下地壳流或昆仑山断裂开始走滑也有关系。这一研究加深了对青藏高原北部变形机制的理解。 | 苏庆达 聂军胜 Joel E. Saylor Brian K. Horton Meredith A. Bush 陈文汉 | 2016 | 第四纪研究2016,36,4: | 8 |
| 2 | 札达盆地晚中新世河湖相沉积物环境磁学特征与印度季风演化显示文摘晚新生代印度季风的演化一直以来是地学研究的热点问题,然而目前对印度季风的研究多集中在海洋沉积物上。磁学参数作为指示气候的重要指标,已被广泛应用于黄土高原等地区的古气候重建中,对揭示东亚季风的演化历史和驱动机制做出了重要的贡献,但利用磁学指标对印度季风变化历史的研究还很稀少。文章运用磁学方法对藏南札达盆地的河湖相厚225.5 m、年龄范围在9.4~6.0 Ma的沉积物进行分析,发现磁学参数值在8.6 Ma前后发生了明显变化,对应沉积环境和岩相的改变(由河流环境和粗颗粒沉积转变为潮上环境和较细的沉积)。8.6 Ma前磁学参数值较高,磁化率(χ)高的原因可能是风化生成的细颗粒含量多导致的,而HIRM高是由于风化形成赤铁矿增多引起的。鉴于研究剖面的沉积速率在8.6 Ma发生了快速的增加以及以前的研究揭示这段沉积物风化程度较低,我们把8.6 Ma后所有的磁学参数值的降低归因于季风增强造成沉积剥蚀搬运速率增加从而导致沉积物来不及风化,细颗粒的亚铁磁性矿物和赤铁矿没有大量生成。考虑到札达盆地记录的气候变湿时间与阿拉伯海叶蜡碳同位素记录的南亚干旱化得以缓解的时间一致,我们认为这些记录共同指示了印度夏季风的增强。在综合分析青藏高原隆升、特提斯海退缩、南北半球冰量变化和印度洋表水温度变化的基础上,我们把印度夏季风的增强归因为南极冰盖的增加或者是青藏高原的向东北扩张。这一研究加深了对印度季风变化历史和驱动机制的认识。 | 王晓雪 聂军胜 Joel Saylor 张蕊 | 2018 | 第四纪研究2018,38,5: | 3 |
| 3 | Bone targeted therapies for the prevention of skeletal morbidity in men with prostate cancer显示文摘有前列腺癌症的人从骨头相关的复杂并发症实质地受苦。雄激素剥夺治疗本身是骨头矿物质密度的损失的一个原因并且与 osteoporotic 破裂的增加的发生被联系。在先进疾病,骨头迄今为止是转移的最普通的地点。骨头转移的复杂并发症显著地为象针的绳索压缩和病理学的破裂那样的骨胳的事件包括疼痛和潜力。提高的骨破折活动由于转移是处理相关的骨质疏松症和骨胳的复杂并发症的 pathophysiology 的一个重要方面。骨破折因此是一个治疗学的目标。Denosumab 是到原子 factor-κ 的受体使活跃之物的充分人的 monoclonal 抗体;被设计 potently 禁止骨破折活动并且是这评论的中央焦点的 -B ligand。象 abiraterone 醋酸盐和 enzalutamide 那样的 Bisphosphonates, radiopharmaceuticals 和 systemically 活跃的神经质的代理人各被显示了处于特定的临床的状况改进骨胳的病态。Denosumab 是被显示了为骨折在收到雄激素剥夺治疗的人并且在提高的风险阻止 osteoporotic 破裂的唯一的代理人。它也与对骨头变形的阉割抵抗的前列腺癌症在人表明了优势到为骨胳相关的事件的预防酸的有势力 bisphosphonate zoledronic。功效和毒性数据将被讨论。 | Philip J Saylor | 2014 | Asian Journal of Andrology2014,16,3: | 2 |
| 4 | Heart rate is an independent predictor of all-cause mortality in individuals with type 2 diabetes: The diabetes heart study显示文摘AIM To assess the association of resting heart rate with allcause and cardiovascular disease(CVD) mortality in the Diabetes Heart Study(DHS).METHODS Out of a total of 1443 participants recruited into the DHS, 1315 participants with type 2 diabetes who were free of atrial fibrillation and supraventricular tachycardia during the baseline exam were included in this analysis. Heart rate was collected from baseline resting electrocardiogram and mortality(all-cause and CVD) was obtained from state and national death registry. Kaplan-Meier(K-M) and Cox proportional hazard analyses were used to assess the association.RESULTS The mean age, body mass index(BMI) and systolic blood pressure(SBP) of the cohort were 61.4 ± 9.2 years, 32.0 ± 6.6 kg/m2, and 139.4 ± 19.4 mmHg respectively. Fiftysix percent were females, 85% were whites, 15% were blacks, 18% were smokers. The mean ± SD heart rate was 69.8(11.9) beats per minute(bpm). After a median follow-up time of 8.5 years(maximum follow-up time is 14.0 years), 258 participants were deceased. In K-M analysis, participants with heart rate above the median had a significantly higher event rate compared with those below the median(log-rank P = 0.0223). A one standard deviation increase in heart rate was associated with allcause mortality in unadjusted(hazard ratio 1.16, 95%CI: 1.03-1.31) and adjusted(hazard ratio 1.20, 95%CI: 1.05-1.37) models. Similar results were obtained with CVD mortality as the outcome of interest.CONCLUSION Heart rate is an independent predictor of all-cause mortality in this population with type 2 diabetes. In this study, a 1-SD increase in heart rate was associated with a 20% increase in risk suggesting that additional prognostic information may be gleaned from this ubiquitously collected vital sign. | Sameer Prasada Cameron Oswalt Phyllis Yeboah Georgia Saylor Donald Bowden Joseph Yeboah | 2018 | World Journal of Diabetes2018,9,1: | 2 |
| 5 | Computer simulation of CO2 trapped through mineral precipitation in the Rose Run Sandstone, Ohio显示文摘 | Zerai B Saylor B Z Matisoff G | 2006 | Applied Geochemistry2006,21,: | 1 |
| 6 | The effect of substrate material on silver nanoparticle antimicrobial efficacy显示文摘 | Dair B J Saylor D M Cargal T E | 2010 | J Nanosci Nanotechn2010,10,12: | 1 |
| 7 | A real-time statistical radar target model显示文摘 | Sandhu G S Saylor A V | 1985 | IEEE Transactions on Aerospace and Electronic Systems1985,10,4: | 1 |
| 8 | The Effects of Curvature on Fluid Flow Fields in Pulmonary Artery Models: Flow Visualization Studies, 显示文摘 | P G Lynch A Saylor B Ha | 1993 | J Biomech Eng (S0148-0731)1993,115,1: | 1 |
| 9 | Monoclonal antibody- based therapies for microbial diseases显示文摘 | Saylor C Dadachova E Casadevall A | 2009 | Vaccine2009,27,6: | 1 |
| 10 | Oncogene amplification in pediatric brain tumors 显示文摘 | Wasson JC Saylors RL Zeltzer P | 1995 | Cancer Res1995,55,: | 1 |
| 11 | Changes in biomarkers of inflammation and angiogenesis during androgen deprivation therapy for prostate cancer显示文摘 | Saylor PJ Kozakkr Smithmr | 2012 | Oncologiat2012,17,2: | 1 |
| 12 | Linear regression techniques for use in the EC tracer method of secondary organic aerosol estimation 显示文摘 | Saylor R D Edgerton E S Hartsell B E | 2006 | Atmospheric Environment2006,40,: | 1 |
| 13 | Maintenance and stability of introduced genotypes in groundwater aquifer material显示文摘 | Jain R K Saylor G S Wilson J T etal | 1987 | Applied and Environmental Microbiology1987,53,: | 1 |
| 14 | Design and implementation of a protocol for the detection of Legionella in clinical and environmental samples显示文摘 | Nazarian E Bopp D Saylors A | 2008 | Diagn Microbiol Infect Dis2008,62,2: | 1 |
| 15 | Computational analysis of the interfacial bonding between feed-powder par-ticles and the substrate in the cold- gas dynamic- spray process 显示文摘 | Grujicic M Saylor J R Beasley D E | 2003 | Applied Surface Science2003,219,34: | 1 |
| 16 | Computational anal- ysis of the interfacial bonding between feed-powder particles and the substrate in the cold-gas dynamic-spray process 显示文摘 | Grujicic M Saylor J R Beasley D E | 2003 | Applied Surface Science2003,219,: | 1 |
| 17 | Efficacy of continuous infusion 2-CDA (cladribine) in pediatric patients with Langerhans cell histiocytosis显示文摘 | Stine KC Saylors RL Saccente S | 2004 | Pediatr Blood Cancer2004,43,1: | 1 |
| 18 | Computer simulation of CO2 trapped through mineral precipitation in the Rose Run Sandstone, Ohio 显示文摘 | Biniam Zerai Beverly Z Saylor G M | 2006 | Apphed Geochemistry2006,21,: | 1 |
| 19 | Effect of dietary phosphorus, phytase,and 25-hydroxycholecalciferol on broiler chicken bone mineralization, litter phosphorus, and processing yields 显示文摘 | Angel R Saylor W W Mitchell A D | 2006 | Poult Sci2006,85,: | 1 |
| 20 | hnpact of ethoxyquin on productivity of dairy cattle显示文摘 | Smith JL Sheffield LG Saylor D | 2002 | Journal of Dairy Science2002,85,1: | 1 |