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| 1 | Iron and non-alcoholic fatty liver disease显示文摘The mechanisms that promote liver injury in non-alcoholic fatty liver disease(NAFLD) are yet to be thoroughly elucidated. As such, effective treatment strategies are lacking and novel therapeutic targets are required. Iron has been widely implicated in the pathogenesis of NAFLD and represents a potential target for treatment. Relationships between serum ferritin concentration and NAFLD are noted in a majority of studies, although serum ferritin is an imprecise measure of iron loading. Numerous mechanisms for a pathogenic role of hepatic iron in NAFLD have been demonstrated in animal and cell culture models. However, the human data linking hepatic iron to liver injury in NAFLD is less clear, with seemingly conflicting evidence, supporting either an effect of iron in hepatocytes or within reticulo-endothelial cells. Adipose tissue has emerged as a key site at which iron may have a pathogenic role in NAFLD. Evidence for this comes indirectly from studies that have evaluated the role of adipose tissue iron with respect to insulin resistance. Adding further complexity, multiple strands of evidence support an effect of NAFLD itself on iron metabolism. In this review, we summarise the human and basic science data that has evaluated the role of iron in NAFLD pathogenesis. | Laurence J Britton V Nathan Subramaniam Darrell HG Crawford | 2016 | World Journal of Gastroenterology2016，22，36： | 14 |
| 2 | Non-HFE haemochromatosis显示文摘Non-HFE 世袭 haemochromatosis (HH ) 指在 HFE 基因被解开到变化的铁超载混乱的一个遗传上异构的组。non-HFE HH 的四种主要类型被变化在 hemojuvelin 引起, hepcidin,转铁蛋白受体 2 并且 ferroportin 基因。少年 haemochromatosis 是正染色体的后退的混乱并且能被变化在 hemojuvelin 或 hepcidin 引起。类似于 HFE-HH 的 HH 的一种成年发作形式被纯合性在转铁蛋白受体 2 为变化引起。正染色体的主导的铁超载混乱 ferroportin 疾病被变化在铁出口商 ferroportin 引起。临床的特征和 non-HFE haemochromatosis 的各种各样的类型的分子的基础被考察。包含的这些混乱和分子的学习在改进我们涉及铁新陈代谢的规定的机制的理解是无价的。 | Daniel F Wallace V Nathan Subramaniam | 2007 | World Journal of Gastroenterology2007，13，35： | 2 |
| 3 | Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus 显示文摘 | Loh E Peter F Subramaniam V N | 2005 | J Cell Sci2005，118，6： | 1 |
| 4 | Blast Response Simulation of an Elastic Structure Evaluation of the Fluid-Structure Interaction Effect显示文摘 | Subramaniam K V Weimin NoYiannis A | 2009 | Int J Impact Eng2009，36，： | 1 |
| 5 | The use of?uorescent dyes and probes in surgical oncolo-gy显示文摘 | TE VELDE E A VEERMAN T SUBRAMANIAM V etal | 2010 | EJSO2010，36，1： | 1 |
| 6 | Factors influencing the careseeking behaviour of chest symptomatics: a community-based study involving rural and urban population in Tamil Nadu, South India 显示文摘 | Sudha G Nirupa C Rajasakthivel M Sivasusbramanian S Sundaram V Bhatt S Subramaniam K Thiruvalluvan E Mathew R Renu G Santhal T | 2003 | Tropical Medicine and International Health2003，8，4： | 1 |
| 7 | Tensile properties of chemically modified ring- and rotor-spun cotton yarns 显示文摘 | SUBRAMANIAM V THAMBIDURAI S | 1995 | Journal of Applied Polymer Science1995，55，7： | 1 |
| 8 | Nonhomologous RNA-RNA recombination events at the 3' nontranslated region of the sindbis virus genome:hot spots and utilization of nonviral sequences显示文摘 | Hajjou M Hill K R Subramaniam S V | 1996 | J Virol1996，70，8： | 1 |
| 9 | Continuous perioperative insulin infusion decreases major cardiovas- cular events in patients undergoing vascular surgery: a prospective, ran- domized trial显示文摘 | Subramaniam B Panziea PJ Novack V Mahmood F Matyal R Mitchell JD Sundar E Bose R Pomposelli F Kersten JR Talmor DS | 2009 | Anesthesiology2009，23，5： | 1 |
| 10 | Comparisons between numerical model and experiments for a direct current plasma flow显示文摘 | Aithal S M Subramaniam V V | 1998 | Journal of of Applied Physics1998，84，7： | 1 |
| 11 | Gas permeable (GP) versus non-GP lens wearers: Accuracy of orthok- eratology in myopia reduction 显示文摘 | Subramaniam SV Bennett ES Lakshminarayanan V | 2007 | Optom Vis Sci2007，84，5： | 1 |
| 12 | Anatomical effects of impact noise显示文摘 | Henderson D Spongr V Subramaniam M Campo P | | 0，，： | 1 |
| 13 | Molecular beacons: Nucleic acid hybridization and emerging applications 显示文摘 | Antony T Subramaniam V | 2001 | Journal of Biomolecular Structure & Dynamics2001，19，3： | 1 |
| 14 | Aqueous phase hydrogenolysis of glycerol to 1,2- propanediol without ex- ternal hydrogen addition显示文摘 | Roy D Subramaniam B Chaudhari R V | 2010 | Catalysis Today2010，156，1： | 1 |
| 15 | Factors influencing the careseeking behaviour of chest symptomatics:a community-based stud involving rural and urban population in Tamil Nadu,South Indi 显示文摘 | Sudha G Nirupa C Rajasakthivel M Sivasusbramanian Sundaram V Bhatt S Subramaniam K Thiruvalluvan EM-athew R Renu G Santhal T | 2003 | TropMed Int Health2003，8，4： | 1 |
| 16 | Neuropilin-1 is expressed by breast cancer stem-like cells and is linked to NF-κB activation and tumor sphere formation显示文摘 | Glinka Y Mohammed N Subramaniam V | | 0，，04： | 1 |
| 17 | Changes in distortion product otoacoustic emissions and outer hair cells following interrupted noise exposures 显示文摘 | Subramaniam M Salvi R J Spong V P | 1994 | Hear Res1994，74，12： | 1 |
| 18 | In situ formation of large-scale Ag/AgCl nanoparticles on layered titanate honeycomb by gas phase reaction for visible light degradation of phenol solution显示文摘 | Tang Y X Subramaniam V P Lau T H | 2011 | Applied Catalysis B:Environmental2011，106，34： | 1 |
| 19 | Auto- mated Water Spread Mapping Using ResourceSat 1 AWiFS Data for Water Bodies Information System 显示文摘 | Subramaniam S Suresh Babu A V Roy P S | 2011 | IEEE Journal of Selected Topics Applied Earth Observations and Remote Sensing2011，4，1： | 1 |
| 20 | Continuous perioperative in sulin infusion decrease major cardiovascular events in patients undergoing vascular surgery: a prospective randomizedtrial显示文摘 | Subramaniam B Panzica P J Novack V | 2009 | Anesthesiology2009，110，5： | 1 |
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