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	题名	作者	年代	出处	被引量
1	Lean heart: Role of leptin in cardiac hypertrophy and metabolism显示文摘Leptin is an adipokine that has been linked with the cardiovascular complications resulting from obesity such as hypertension and heart disease. Obese patients have high levels of circulating leptin due to increased fat mass. Clinical and population studies have correlated high levels of circulating leptin with the development of cardiac hypertrophy in obesity. Leptin has also been demonstrated to increase the growth of cultured cardiomyocytes. However, several animal studies of obese leptin deficient mice have not supported a role for leptin in promoting cardiac hypertrophy so the role of leptin in this pathological process remains unclear. Leptin is also an important hormone in the regulation of cardiac metabolism where it supports oxidation of glucose and fatty acids. In addition, leptin plays a critical role in protecting the heart from excess lipid accumulation and the formation of toxic lipids in obesity a condition known as cardiac lipotoxicity. This paper focuses on the data supporting and refuting leptin's role in promoting cardiac hypertrophy as well as its important role in the regulation of cardiac metabolism and protection against cardiac lipotoxicity.	Michael E Hall Romain Harmancey David E Stec	2015	World Journal of Cardiology2015，7，9：	7
2	Resistance to first line platinum paclitaxel chemotherapy in serousepithelial ovarian cancer: The prediction value of ERCC1 and Tau expression显示文摘	Karina Steffensen Marta Smoter Marianne Waldstr?m Bart?omiej Grala Lubomir Bodnar Rafa? Stec Cezary Szczylik Anders Jakobsen	2014	International Journal of Oncology2014，，5：	2
3	Functional polymorphism in human CYP4F2 decreases 20-HETE production显示文摘	Stec DE Roman RJ Flasch A		0，，01：	1
4	The Evolution of Apical Dominance in Maize 显示文摘	DOEBLEY J STEC A HUBBARD L	1997	Nature1997，386，3：	1
5	The evolution of apical dominance in maize显示文摘	DOEBLEY J Stec A Hubbard L	1991	Nature1991，386，：	1
6	Moderate hyperbilirubinemiaimproves renal hemodynamics in ANGⅡ-dependenthypertension显示文摘	VERA T STEC D E	2010	Am J Physiol Regul Integr CompPhysiol2010，299，：	1
7	A revised mechanism for the alkaline phosphatase reaction involving three metal ions显示文摘	Stec B Holtz KM Kantrowitz R	2000	J Mol Bio2000，299，5：	1
8	Novel mechanism of hypertensionrevealed by cell-specific targeting of human angiotensinogen in transge-nic mice显示文摘	Davisson RL Ding YM Stec DE	1999	Physiol Genomics1999，1，1：	1
9	Genetic and morphological analysis of a maize-teosinte F2 population: implications for the origin of maize显示文摘	Doebley J Stec A Wendel J	1990	Proceedings of the National Academy of Sciences1990，87，24：	1
10	WHSC1, a 90 kb SETdomain containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps to theWolf- Hirschhorn syndrome critical region and is fused to IgH in t (4 ; 14) multiole mvloma显示文摘	Stec I Wright TJ van Ommen GJB	1998	Hum Mol Genet1998，7，：	1
11	The evolution of apical dominance in maize 显示文摘	Deobely J Stec A O Hubbard L	1997	Nature1997，386，6624：	1
12	Cyclophosphamide and its congeners 显示文摘	Stec W J	1982	Organophosphorous Chem1982，13，：	1
13	Modelling the double skin facade with plants显示文摘	STEC W J VAN PAASSEN A H C MAZIARZ A	2005	Energy and Buildings2005，37，5：	1
14	Long-term prognostic value of an index of myocardial performance in patients with myocardial infarction显示文摘	Szymanski P Rezler J Stec S	2002	Clin cardiol2002，25，8：	1
15	Heme oxygenase inhibition increases blood pressure in pregnant rats显示文摘	George EM Hosick PA Stec DE	2013	Am J Hypertens2013，26，7：	1
16	Extrasystolic beats affect transmural electrical dispersion during programmed electrical stimulation显示文摘	WOLK R STEC S KULAKOWSKI P	2001	Eur J Clin Investig2001，31，：	1
17	Functional polymor- phism in human CYP4F2 decreases 20-HETE production 显示文摘	Stec DE Roman RJ Flasch A	2007	PhysiolGenomic2007，30，1：	1
18	A cell-based beta-lactamase reporter gene assay for the identification of inhibitors of hepatitis C virus replication显示文摘	Zuck P Murray EM Stec E	2004	Anal Biochem2004，334，2：	1
19	Association of fibrinogen with cardiovascular risk factors and cardiovascular disease in the Framingham off-spring population 显示文摘	Stec J J Silbershatz H Tofler G H	2000	Circulation2000，102，14：	1
20	Expression of heme oxygen- ase-1 in thick ascending loop of henle attenuates angiotensin Ⅱ- dependent hypertension显示文摘	Stec DE Drummond HA Gousette MU Storm MV Abraham NG Csongradi E	2012	J Am Soc Nephrol2012，23，5：	1

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