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| 1 | Effect of B vitamin supplementation on plasma homocysteine levels in celiac disease显示文摘AIM: To investigate the effect of vitamin supplements on homocysteine levels in patients with celiac disease. METHODS: Vitamin B6, folate, vitamin B12, and fasting plasma homocysteine levels were measured in 51 consecutive adults with celiac disease [median (range) age 56 (18-63) years; 40% men, 26 (51%) had villous atrophy, and 25 (49%) used B-vitamin supplements] and 50 healthy control individuals matched for age and sex. Finally, the C677T polymorphism of 5,10-methylene tetrahydrofolate reductase (MTHFR) was evaluated in 46 patients with celiac disease and all control individuals. RESULTS: Patients with celiac disease and using vitamin supplements had higher serum vitamin B6 (P = 0.003),folate (P < 0.001), and vitamin B12 (P = 0.012) levels than patients who did not or healthy controls (P = 0.035, P < 0.001, P = 0.007, for vitamin B6, folate, and vitamin B12, respectively). Lower plasma homocysteine levels were found in patients using vitamin supplements than in patients who did not (P = 0.001) or healthy controls (P = 0.003). However, vitamin B6 and folate, not vitamin B12, were significantly and independently associated with homocysteine levels. Twenty-four (48%) of 50 controls and 23 (50%) of 46 patients with celiac disease carried the MTHFR thermolabile variant T-allele (P = 0.89). CONCLUSION: Homocysteine levels are dependent on Marsh classification and the regular use of B-vitamin supplements is effective in reduction of homocysteine levels in patients with celiac disease and should be considered in disease management. | Muhammed Hadithi Chris JJ Mulder Frank Stam Joshan Azizi J Bart A Crusius Amado Salvador Pea Coen DA Stehouwer Yvo M Smulders | 2009 | World Journal of Gastroenterology2009，15，8： | 3 |
| 2 | Enhanced biodegradation of aromatic pollutants in cocultures of anaerobic and aerobic bacterial consortia 显示文摘 | FELDJ A STAMS A J M KATO M | 1995 | Antonievall Leeuwenhoek1995，67，： | 1 |
| 3 | Theoretical proportion of donor genome in nearisogenic lines of self-fertilizers bred byback-crossing显示文摘 | Stam P Zeven A C | 1981 | Euphytica1981，30，： | 1 |
| 4 | Ventilator-Associated Pneumonia and Frequency of Circuit Changes显示文摘 | Stam A M | 1998 | Am J Infect Control1998，26，1： | 1 |
| 5 | Metabolic interactions between anaerobic bacteria in methanogenie environments 显示文摘 | Stams A J M | 1994 | Antonie Van Leeuwen hoek1994，66，： | 1 |
| 6 | Electron transfer in syntrophic communities of anaerobic bacteria and archaea 显示文摘 | Stams A J M Plugge C M | 2009 | Nat Rev Microbiol2009，7，： | 1 |
| 7 | On multiplicative priority rating methods for the AHP显示文摘 | Stam A Duarte Silva A P | 2003 | European Journal of Operational Research2003，145，1： | 1 |
| 8 | On multiplicative priority rating methods for the AHP 显示文摘 | STAM P SILVA A D | 2003 | European Journal of Operational Research2003，145，1： | 1 |
| 9 | Growthand substrate-dependent transcription of formate dehydrogenase and hydrogenase coding genes in Syntrophobacter fumaroxidans and Methanospirillum hungatei显示文摘 | WORM P STAMS A J M CHENG X | | 0，，： | 1 |
| 10 | Rapid generation of antigenpresenting cells from leukaemic blasts in acute myeloid leukaemia显示文摘 | Westers T M Stam A M Scheper R M | 2003 | Cancer Immunol Immunotherapy2003，52，8： | 1 |
| 11 | Pathway of propionate oxidation by a syntrophic culture of Smithella propionica and Methanospirillum hungatei显示文摘 | De Bok Fa M Stams A J M Dijkema C Boone D R | 2001 | Applied and Environmental Microbiology2001，67，4： | 1 |
| 12 | Enhanced biodegradation of aromatic pollutants in cocultures of anaerobic and aerobic bacterial consortia 显示文摘 | Field J A Stams A J M Kato M | 1995 | Antonie van Leeuwenhoek1995，67，1： | 1 |
| 13 | Reducing Conflict between Marketing and Manufacturing显示文摘 | CRITTENDEN V L GARDINER L R STAM A | 1993 | Industrial Marketing Management1993，22，： | 1 |
| 14 | Position measurement of non-integer OAM beams with structurally invariant propagation显示文摘 | Nugrowati A M Stam W G Woerdman J P | 2012 | Optics Express2012，20，27： | 1 |
| 15 | Effects of Thermomechanical Cycling on Lead and Lead-Free (SnPb and SnAgCu) Surface Mount Solder Joints显示文摘 | Stam F A Davitt E | 2001 | Microelectronics Reliability2001，41，： | 1 |
| 16 | On muhiplicative priority rating methods for the AHP 显示文摘 | Antonie Stam A Pedro Duarte Silva | 2003 | European Journal of Operational Research2003，145，1： | 1 |
| 17 | Electron transfer in syntrophic communities of anaerobic bacteria and archaea显示文摘 | Stams A J M Plugge C M | 2009 | Nat Rev Microbiol2009，7，： | 1 |
| 18 | Cognitive and neurological outcome at the age of 5- 8 years of preterm infants with post-hemorrhagic ventricular dilatation requi- ting neurosurgical intervention 显示文摘 | Brouwer AJ van Stam C Uniken Venema M et a/ | 2012 | Neonatology2012，101，3： | 1 |
| 19 | Metabolic interactions between anaerobic bacteria in metbanogenic environments显示文摘 | Stams A J M | 1994 | Antonie Van Leeuwenhoek1994，66，： | 1 |
| 20 | Graph theoret- ical analysis of magnetoencephalographic functional con- nectivity in Alzheimer' s disease 显示文摘 | Stam C J Haan W de Daffertshofer A | 2009 | Brain2009，132，9： | 1 |
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