|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 文化生态理念下的历史街区保护与更新研究--以武汉市青岛路历史街区为例显示文摘在全球化及在全球可持续发展理念及'人本主义'思想影响下,如何在保护历史街区的前提下延续城市文脉、提升区域的活力、创造与时代背景相融合的新文化,仍然是当前历史街区保护与更新需要重点研究的课题。武汉市青岛路历史街区保护与更新规划基于文化生态理念,从物质文化形态层面、文化与社会经济层面及文化价值与社会民生层面提出规划重点。 | 黄焕 Bert Smolders Jos Verweij | 2010 | 规划师2010，26，5： | 34 |
| 2 | TAT-Gap19通过抑制啮齿动物星形胶质细胞的连接蛋白43半通道发挥抗惊厥作用显示文摘越来越多的证据表明,星形胶质细胞连接蛋白43(Cx43)信号在癫痫中发挥至关重要的作用。但是,由于通过实验方法鉴别Cx43间隙连接通道(GJCs)和半通道(HCs)的技术尚不成熟,导致目前尚无法确定哪个通道在癫痫的发生中发挥更重要的作用。因此,本研究观察TAT-Gap19(Cx模拟肽)是否通过抑制Cx43半通道而非Cx43间隙连接通道影响实验诱导的啮齿动物癫痫发作。急性海马切片小鼠染料摄取实验表明,星形胶质Cx43半通道响应化学惊厥毛果芸香碱的作用而开放,并且可被TAT-Gap19抑制。体内实验中,毛果芸香碱诱导的癫痫发作及相伴随的D-丝氨酸微透析液的增长水平被Cx43半通道的抑制所抑制。此外,TAT-Gap19的抗惊厥作用被外源性D-丝氨酸给药逆转,这表明,抑制Cx43半通道可以通过降低细胞外D-丝氨酸水平来防止癫痫发作。抑制Cx43半通道的抗惊厥特性在电癫痫小鼠模型(如急性6 Hz难治性癫痫发作模型和慢性6 Hz角膜点燃模型)中得到了进一步的证实。总而言之,这些结果表明,Cx43半通道在癫痫发作中可以起到一定作用,并且有成为癫痫治疗中新型用药靶点的潜力。 | Walrave L Pierre A Albertini G Aourz N De Bundel D Van Eeckhaut A Vinken M Giaume C Leybaert L Smolders I 聂昊 | 2018 | 神经损伤与功能重建2018，13，6： | 5 |
| 3 | Phosphorus removal from wastewater by anaerobic-anoxic sequencing batch reactor显示文摘 | Kuba T Van Loosdrecht M C M Smolders G | 1993 | War Sci Tech1993，27，56： | 2 |
| 4 | Future trends in soil cadmium concentration under current cadmium fluxes to European agricultural soils显示文摘 | L. Six E. Smolders | 2014 | Science of the Total Environment2014，，： | 2 |
| 5 | Under proper control, oxidation of proteins with known chemical structure provides an accurate and absolute method for the determination of their molar concentration显示文摘 | Guermant C Azarkan M Smolders N | 2000 | Anal Biochem2000，277，： | 1 |
| 6 | Predicting availability of miner- al elements to plants with the DGT technique: A review of experimental data and interpretation by modeling显示文摘 | Degryse F Smolders E Zhang H | 2009 | Environmental Chemistry2009，，6： | 1 |
| 7 | Toxicity of heavy metals in soil assessed with various soil microbial and plant growth assays: a comparative study显示文摘 | Broos K Mertens J Smolders E | 2005 | Environmental Toxicology and Chemistry2005，24，3： | 1 |
| 8 | Lead phytotoxicity in soils and nutrient solutions is related to lead induced phosphorus deficiency显示文摘 | Karlien Cheyns Sofie Peeters Dorien Delcourt Erik Smolders | 2012 | Environmental Pollution2012，，： | 1 |
| 9 | Pulse jet cleaning of rigid filters:A literature review and introduction to process modeling显示文摘 | Schildermans I Baeyens J Smolders K | | 0，，05： | 1 |
| 10 | Safety and T cell modulating effects of high dose vitamin D3 supplementation in multiple sclerosis 显示文摘 | Smolders J Peelen E Thewissen M | 2010 | PLoS One2010，5，12： | 1 |
| 11 | Rewarding, reinforcingand incentive salient events involve orexigenic hypo-thalamic neuropeptides regulating mesolimbic dopam-inergic neurotransmission 显示文摘 | QUARTA D SMOLDERS I | 2014 | European Journal ofPharmaceutical Sciences2014，57，： | 1 |
| 12 | A structured metabolic model for the anaerobic and aerobic stoichiometry and kinetics of the biological phosphorus removal process显示文摘 | G J F Smolders | 1995 | Biotechnology and Biocngineering1995，47，： | 1 |
| 13 | Bioligical phosphorus removal from wastewater by anaerobic-aerobic se- quencing batch reaetor显示文摘 | Kuba T Smolders G van Loosdreeht M C M | 1993 | 27(5-6) : 241-2421993，27，56： | 1 |
| 14 | Metal complexes increase uptake of Zn and Cu by plants:Implications for uptake and deficiency studies in chelator-buffered solutions显示文摘 | Degryse F Smolders E Parker D R | 2006 | Plant Soil2006，289，： | 1 |
| 15 | The mechanism of formation of microporous or skinned membranes produced by immersion precipitation显示文摘 | Wijimans J G Baaij J P B Smolders C A | 1983 | J Membr Sci1983，14，： | 1 |
| 16 | Effect of Cl on Cd uptake by swiss chard in nutrient solutions显示文摘 | SMOLDERS E MCLAUGHLIN M J | 1996 | Plant and Soil1996，179，： | 1 |
| 17 | Development of lymphocyte subpopulations in preterm infants 显示文摘 | Walker JC Smolders MA Gemen EF | 2011 | Scand J Immunol2011，73，1： | 1 |
| 18 | Biological phosphorus removal from wastewater by anaerobic-anoxic sequencing batch reactor 显示文摘 | Kuba T Smolders G van Loosdrecht M C M | 1993 | Water Science and Technology1993，27，56： | 1 |
| 19 | Model of the anaerobic metabolism of the biological phosphorus removal process:stoichionetry and pH influence显示文摘 | Smolders G J F Van der Meij J Van Loosdrecht M C M | 1994 | Biotechnology and Bioengineering1994，43，： | 1 |
| 20 | Model of the anaerobic metabolism of the biological phosphorus removal process:stoichiometry and pH influence显示文摘 | Smolders G J F Der M V J Van Loodrecht M C M | 1994 | Biotechnol Bioeng1994，43，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员