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| 1 | Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension显示文摘 | Sitbon O Humbert M Jais X | | 0，，： | 2 |
| 2 | Vacuole Integrity Maintained by DUF300 Proteins Is Required for Brassinosteroid Signaling Regulation显示文摘Brassinosteroid (BR ) 荷尔蒙发信号在植物生长和开发期间控制多重进程并且和象联系 BRI1 的受体 KINASE1 (BAK1 ) 那样的合作受体通过受体 kinase BRASSINOSTEROID INSENSITIVE1 (BRI1 ) 在血浆膜被开始。BRI1 丰富被 endosomal 再循环并且 vacuolar 指向调整,但是在 BR 受体动力学和 BR 回答的液泡相关的蛋白质的角色留下逃犯。这里,我们证明 BR 发信号的二 DUF300 包含域的 tonoplast 蛋白质, LAZARUS1 (LAZ1 ) 和 LAZ1 HOMOLOG1 (LAZ1H1 ) 的缺席,原因液泡形态学缺点,生长抑制,和组成的激活。有趣地, BAK1 的 tonoplast 累积实质地被增加并且显得有原因地在 laz1 laz1h1 植物连接了到提高的 BRI1 trafficking 和降级。因为无关的液泡异种展出了正常 BR 回答,我们的调查结果显示 DUF300 蛋白质在由维持要求平衡 subcellular BAK1 水池和 BR 受体分发的液泡正直发信号的 BR 的规定起不同作用。 | Qinsong Liu Thomas Vain Corrado Viotti Siamsa M, Doyle Danuse Tarkowska Ondrej Novak Cyril Zipfel Folke Sitbon Stephanie Robert Daniel Hofius | 2018 | Molecular Plant2018，11，4： | 2 |
| 3 | Drug therapy:treatment of pulmonary arterial hypertension显示文摘 | Humbert M Sitbon O Simonneau G | 2004 | N Engl J Med2004，351，14： | 1 |
| 4 | Prognestic factors for survival in human immunodeficency virus-associated pulmonary arterial hypertension显示文摘 | Nunes M Humbert M Sitbon O | 2003 | Am J Respir Crit Med2003，167，2： | 1 |
| 5 | Treatment of pulmonary arterial hypertension 显示文摘 | Humbert M Sitbon O Simonneau G | 2004 | N Engl J Med2004，351，14： | 1 |
| 6 | Rapid switch from intravenous epoprostenol to intravenous treprostinil in patients with pulmonary arterial hypertension显示文摘 | Sitbon O Manes A Jais X | 2007 | J Cardiovasc Pharmacol2007，49，： | 1 |
| 7 | Long-term intravenous epoprostenol infusion in primary pulmonary hypertension:prognostic factors and survival显示文摘 | Sitbon O Humbert M Nunes h | 2002 | J Am Coll Cardiol2002，40，4： | 1 |
| 8 | Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension:a randomized placebo-controlled study显示文摘 | Channick R N Simonneau G Sitbon O | 2001 | Lancet2001，358，9287： | 1 |
| 9 | Long-term response to calcium channel blockers in idiopathic pulmonary hypertension显示文摘 | Sitbon O Humbert M Jas X | 2005 | Circulation2005，111，： | 1 |
| 10 | Long term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival显示文摘 | Sitbon O Humbert M Nuncs H | 2002 | J Am Coll Cardiol2002，40，4： | 1 |
| 11 | Immunosuppressive therapy in connective tissue diseases-associated pulmonary arterial hypertension显示文摘 | Sanchez O Sitbon O Ja?s X | 2006 | Chest2006，130，1： | 1 |
| 12 | Characterization of pulmonary arterial hypertension patients walking more than 450 m in 6 min at diagnosis显示文摘 | Degano B Sitbon O Savale L | 2010 | Chest2010，137，6： | 1 |
| 13 | Treatment of pulmonary arterial hypertension显示文摘 | Humbert M Sitbon O Simonneau G | 2004 | N Engl J Med2004，351，14： | 1 |
| 14 | The effects of first-line bosenton on survival of patients with primary pulmonary hypertension显示文摘 | Sitbon O Mclaughlin V Rubin L J | 2003 | Am J Respir Crit Care Med2003，167，： | 1 |
| 15 | Prognostic factors for suvival in Humanlmmunodeficiency Virus-associated pulmonary arterial hypertension显示文摘 | NUNES H HUMBERT M SITBON O | 2003 | Am J Respir Crit Med2003，167，10： | 1 |
| 16 | Transgenic tobacco plants coexpressing the Agrobacterium tumefaciens iaaM and iaaH genes display altered growth and Indoleacetic acid metabolism显示文摘 | Sitbon F B Hennion S Sundberg B | | 0，，03： | 1 |
| 17 | Long-term response to calcium channel blockers in idiopathic pulmonary arte- rial hypertension 显示文摘 | Sitbon O Humbert M Jais X | 2005 | Circulation2005，111，23： | 1 |
| 18 | 肺动脉高压启动治疗后血流动力学指标的预后价值显示文摘血流动力学指标,如心脏指数和右心房压力(right atrial pressure,RAP)与患者确诊肺动脉高压时的生存率持续相关。近期研究表明,肺动脉顺应性(pulmon aryarterial compliance,Pea)也可能预测肺动脉高压的预后。而在治疗开始之后测定的血流动力学指标对预后的价值还未确定。 | 黄洁 叶鹏 Weatherald J Boucly A Chemla D Savale L Peng M Jevnikar M Ja?s X Taniguchi Y O'Connell C Parent F Sattler C Hervé P Simonneau G Montani D Humbert M Adir Y Sitbon O | 2017 | 中华高血压杂志2017，25，11： | 1 |
| 19 | Risk factors for pulmonaryarterial hypertension显示文摘 | HUMBERT M NUNES H SITBON O | 2001 | Clin Chest Med2001，22，： | 1 |
| 20 | Long-term intravenous epoprostenol infusion in primary pulmonary hypertension:prognostic factors andsurvival显示文摘 | Sitbon O Humbert M Nunes H | 2002 | J Am Coll Cardiol2002，40，4： | 1 |
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