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| 1 | Relative efficacy of some prokinetic drugs in morphine-induced gastrointestinal transit delay in mice显示文摘AIM: To study the relative efficacy of cisapride,metoclopramide, domperidone, erythromycin and mosapride on gastric emptying (GE) and small intestinal transit (SIT)in morphine treated mice.METHODS: Phenol red marker meal was employed to estimate GE and SIT in Swiss albino mice of either sex. The groups included were control, morphine 1 mg/kg (s.c. 15min before test meal) alone or with (45 min before test meal p.o.) cisapride 10 mg/kg, metoclopramide 20 mg/kg,domperidone 20 mg/kg, erythromycin 6 mg/kg and mosapride 20 mg/kg.RESULTS: Cisapride, metoclopramide and mosapride were effective in enhancing gastric emptying significantly (P<0.001)whereas other prokinetic agents failed to do so in normal mice. Metoclopramide completely reversed morphine induced delay in gastric emptying followed by mosapride.Metoclopramide alone was effective when given to normal mice in increasing the SIT. Cisapride, though it did not show any significant effect on SIT in normal mice, was able to reverse morphine induced delay in SIT significantly (P<0.001)followed by metoclopramide and mosapride.CONCLUSION: Metoclopramide and cisapride are most effective in reversing morphine-induced delay in gastric emptying and small intestinal transit in mice respectively. | AD Suchitra SA Dkhar DG Shewade CH Shashindran | 2003 | World Journal of Gastroenterology2003，9，4： | 3 |
| 2 | Improved osseointegration of titanium implants of different surface characteristics by the use of bone morphogenetic protein ( BMP-3 ) : an animal study performed at the metaphyseal bone bed in dogs显示文摘 | Hartwig CH Esenwein SA Pfund A | 2003 | Z Orthop Ihre Grenzgeb2003，141，6： | 1 |
| 3 | Functional polymorphisms of the cytochrome P450 1A2(CYP1A2) gene and prolonged QTc in- terval in schizophrenia显示文摘 | Tay JKX Tan CH Chong SA | 2007 | Prog Neuropsychopharmacol Biol Psy- chiatry2007，31，6： | 1 |
| 4 | Caveolin-1 maintains activated Akt in prostate cancer cells through scaffolding domain binding site interactions with 45 and inhibition of serine/threonine protein phosphatases PP1 and PP2A显示文摘 | Li L Ren CH Tahir SA | 2003 | Mol CeU Biol2003，23，24： | 1 |
| 5 | Qualification of in plane motion of the coronary arteries during the cardiac cycle:implications for acquisition window duration for MR flow qualification显示文摘 | Hoffman MB Wickline SA Lorenz CH | 1998 | J Magn Reson Imaging1998，8，3： | 1 |
| 6 | Polymorphisms of dopamine receptors and tardive dyskinesia among Chinese patients with schizophrenia显示文摘 | Chong SA Tan EC Tan CH | 2003 | Am J Med Genet2003，116，1： | 1 |
| 7 | Chimeric antigen receptor-and TCR-modified T cells enter main street and wall street显示文摘 | Barrett DM Grupp SA June CH | 2015 | J Immunol2015，195，3： | 1 |
| 8 | Successful treatment with cyclophosphamide of life-threatening diffuse hemangiomatosis involving the liver显示文摘 | Hurvitz SA Hurvitz CH Sloninsky L | | 0，，： | 1 |
| 9 | Clinical, electr ophysi- ological subtypes and antiganglioside antibodies in childhood Guillain-Barre syndrome显示文摘 | Kannan MA Ch PK Jabeen SA et a/ | 2011 | Neurol India2011，59，5： | 1 |
| 10 | Systemic light chain deposition dis- ease presenting as multiple pulmonary nodules: a case report and review of the literature显示文摘 | Kijner CH Yousem SA | 1988 | Am J Surg Pathol1988，12，5： | 1 |
| 11 | TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors显示文摘 | Cebola I Rodriguez-Segui SA Cho CH | 2015 | Nat Cell Biol2015，17，61： | 1 |
| 12 | Chlamydiae Pueumoniae activates NF-κB and AP-1 in human vascular smooth muscle and induces cellular proliferation显示文摘 | Miller SA Selzman CH Shames BD Barton HA Johnson SM Harken AH | 2000 | J Surg Res2000，90，1： | 1 |
| 13 | Functional characterization of polymorphisms in DNA repair genes using cytogenetic challenge assays显示文摘 | Au WW Salama SA Sierres CH | 2003 | Environ Health Perspect2003，111，15： | 1 |
| 14 | Monocyte chemotactic protein-1directly induces human vascular smooth muscle proliferation显示文摘 | Selzman CH Miller SA Zimmerman MA | 2002 | Am J Physiol Heart Circ Physio2002，283，4： | 1 |
| 15 | Monozygotic twin discordant for Down syndrome; runs 47,XX, +21/46,XX and 46,XX显示文摘 | Choi SA Ko JM Shin CH | 2013 | Eur J Pediatr2013，172，8： | 1 |
| 16 | Enterococcus faecalis:its role in root canal treatment failure and current concepts in retreat- ment显示文摘 | Stuart CH Schwartz SA Beeson TJ | 2006 | J Endond2006，32，2： | 1 |
| 17 | Migration of human umbilical cord blood mesenchymal stem cells mediated by stromal cell-derived factor-1/CXCR4 axis via Akt,ERK,and p38 signal transduction pathways显示文摘 | Ryu CH Park SA Kim SM | | 0，，01： | 1 |
| 18 | Proteolytic processing and primary structure of Plasmodium falciparum apical membrane antigen 1显示文摘 | Howell SA Withers-martinez C Kocken CH | | 0，，33： | 1 |
| 19 | Enteroeoccus faeca- lis : its role in root canal treatment failure and current concepts in retreatment显示文摘 | Stuart CH Schwartz SA Beeson TJ | 2006 | J Endod2006，32，2： | 1 |
| 20 | CXCR4-transfected human umbilical cord blood-derived mesenchymal stem cells exhibit enhanced migratory capacity toward gliomas显示文摘 | Park SA Ryu CH Kim SM | | 0，，01： | 1 |
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