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| 1 | Mechanisms of immune checkpoint inhibitormediated liver injury显示文摘The immune checkpoints,cytotoxic T-lymphocyte-associated antigen 4(CTLA-4) and programmed cell death protein-1/ligand-1(PD-1/PD-L1) are vital contributors to immune resulation and tolerance.Recently immune checkpoint inhibitors(ICIs) have revolutionized cancer therapy;however,they come with the cost of immune related adverse events involving multiple organs such as the liver.Due to its constant expo sure to foreign antigens,the liver has evolved a high capacity for immune tolerance,therefore,blockade of the immune checkpoints can result in aberrant immune activation affecting the liver in up to 20% of patients depending on the agent(s) used and underlying factors.This type of hepatotoxicity is termed immune mediated liver injury from checkpoint inhibitors(ILICI) and is more common when CTLA4 and PD-1/PDL1 are used in combination.The underlying mechanisms of this unique type of hepatotoxicity are not fully understood;however,the contribution of CD8^(+) cytotoxic T lymphocytes,various CD4^(+) T cells populations,cytokines,and the secondary activation of the innate immune system leading to liver injury have all been suggested.This review summarizes our current understanding of the underlying mechanisms of liver injury in immunotherapy using animal models of ILICI and available patient data from clinical studies. | Layla Shojaie Myra Ali Andrea Iorga Lily Dara | 2021 | Acta Pharmaceutica Sinica B2021，11，12： | 6 |
| 2 | Ag/TiO_2/freeze-dried graphene nanocomposite as a high performance photocatalyst under visible light irradiation显示文摘Ag/TiO_2/freeze-dried graphene nanocomposites have been prepared via a facile one-step solvothermal method for the photocatalytic degradation of Rh B under visible light irradiation. During the solvothermal process, reduction of graphene oxide and loading of Ag/TiO_2 nanoparticles on graphene sheets were achieved. Investigation of chemical state of products showed that covering of Ag/TiO_2 surface with higher weight ratio of graphene resulting in that Ag metals in Ag/TiO_2 were oxidized to Ag2 O in nanocomposite structure after solvothermal process. Degree of photocatalytic activity enhancement strongly depends on the coverage of Ag/TiO_2 surface by porous graphene. The sample of 1 wt% porous graphene hybridized Ag/TiO_2 showed the highest photocatalytic activity, which is related to high migration efficiency of photoinduced of electrons and reduction of electron–hole recombination rate due to high electrical conductivity of graphene. Expanding of absorption to visible light region was ascribed to surface plasmon resonance effect of Ag metals and presence of graphene. Investigation of photocatalytic performance of formic acid as a dye-less organic pollutant showed that dye sensitization effect of Rh B molecules during evaluation of photocatalytic performance was negligible. | Ziaeddin Jafari Nader Mokhtarian Ghader Hosseinzadeh Mousa Farhadian Asghar Faghihi Farideh Shojaie | 2016 | Journal of Energy Chemistry2016，25，3： | 4 |
| 3 | Electrostatic and electrosteric stabilization of aqueous slip s of 3Y-ZrO2powder 显示文摘 | Shojai F Pettersson A B A Mantyla T | 2000 | J Eur Ceram Soc2000，20，3： | 2 |
| 4 | Metabolomie profiling reveals potential markers and bioprocesses altered in bladder cancer progression 显示文摘 | Putluri N Shojaie A Vasu VT | 2011 | Cancer Res2011，71，24： | 1 |
| 5 | The comparison of photocatalytic activity of synthesized TiO2 and ZrO2 nanosize onto wool fibers显示文摘 | MOAF! H F SHOJAIE A F ZANJANCHI M A | 2010 | Applied Surface Science2010，256，： | 1 |
| 6 | La3+ and Zr4+ co-doped anatase nano TiO2 by sol-microwave method显示文摘 | SHOJAIE A F LOGHMANI M H | 2010 | Chemical Engineering Journal2010，157，： | 1 |
| 7 | Protein Z in patients with pregnancy complications 显示文摘 | Bretelle F Arnoux D Shojai R | 2005 | Am J Obstet Gynecol2005，193，5： | 1 |
| 8 | Recycling of PVC wastes显示文摘 | Mehdi Sadat Shojai Gholam-Reza Bakhshandeh | 2011 | Polymer Degradation and Stability2011，96，4： | 1 |
| 9 | Protein Z in Patients with pregnancy complications显示文摘 | Bretelle F Amoux D Shojai R | 2009 | Am J Obstet Gynecol2009，193，5： | 1 |
| 10 | Diffusion-weighted magnetic resonance imaging with apparent diffusion coefficient (ADC) determination in normal and pathological fetal kidneys 显示文摘 | Chaumoitre K Colavolpe N Shojai R | 2007 | Ultrasound Obstet Gyneco12007，29，1： | 1 |
| 11 | Effect of sintering temperature and holding time on the properties of 3 Y-ZrO2 microfiltration membranes 显示文摘 | Shojai F Mantyla T A | 2001 | Journal of Materials Science2001，36，： | 1 |
| 12 | Incidence of nosoco- mial infection in selected cities according NISS software in Mazan- daran province 显示文摘 | Cherati JY Shojai J Chaharkameh A | 2015 | Journal of Mazandaran University of Medical Sciences2015，24，122： | 1 |
| 13 | Synthesis methods for nanosized hydroxyapatite with diverse structures 显示文摘 | SADAT - SHOJAI M KHORASANI M T DINPANAH - KHOSHDARGI E | 2013 | Acta Bio- mater2013，9，8： | 1 |
| 14 | The comparison of photocatalytic activity of synthesized TiO2 and ZrO2 nanosize onto wool fibers显示文摘 | HADI Fallah Moafi ABDOLLAH Fallah Shojaie MOHAMMAD Ali Zanjanchi | 2010 | Applied Surface Science2010，256，： | 1 |
| 15 | The prevalence of pre-hypertension and its association to established cardiovascular risk factors in south of Iran显示文摘 | Rahmanian K Shojaie M | 2012 | BMC Res Notes2012，5，2： | 1 |
| 16 | Diffusion-weighted magnetic resonance imaging with apparent diffusion coefficient (ADC) determination in normal and pathological fetal kidneys显示文摘 | Chaumoitre K Colavolpe N Shojai R | 2007 | Ultrasound Obstet Gyneco12007，29，1： | 1 |
| 17 | Metabolomic profiling reveals potential markers and bioprocesses altered in bladder cancer progression显示文摘 | Putluri N Shojaie A Vasu VT | 2011 | Cancer Res2011，71，24： | 1 |
| 18 | Photoactive behavior of polyacrylonitrile fibers based on silver and zirconium co- doped titania nanocomposites : synthesis, characterization, and comparative study of solid-phase photocatalytic self-cleaning 显示文摘 | HADI Fallah Moafi ABDPLLAH Fallah Shojaie MOHAMMAD Ali Zanjanchi | 2013 | Applied Polymer Science2013，127，5： | 1 |
| 19 | Advanced combined abdominal and intrauterine pregnancy:a case report显示文摘 | Shojai R Chaumoitre K Chau C | 2007 | Fetal Diagn Ther2007，22，2： | 1 |
| 20 | Rectal misoprostol for postpartumhemorrhage显示文摘 | Shojai R Desbrière R Dhifallah S | 2004 | Gynecol Obstet Fertil2004，32，9： | 1 |
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