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| 1 | 扩展的节点电价算法研究显示文摘首先回顾了最优潮流与安全约束经济调度问题,重点讨论了节点边际电价算法原理。着重分析了在非凸性条件下,基于安全约束机组组合与经济调度算法产生的节点边际电价机制存在的缺陷,阐述了如何利用扩展的节点边际电价机制,减少额外支付成本,促进实现激励相容的定价机制。然后,利用对偶原理,对于典型定价机制,即:Convex Hull Price、节点边际电价、整数松弛定价,产生的额外支付成本给出了严格的理论证明,并从几何角度说明其物理意义。最后,实现了混合整数规划与拉格朗日松弛2种机组组合优化算法。算例结果表明文中提出的节点边际电价与整数松弛定价的额外支付成本与Convex Hull Price最小额外支付成本之间关系原理的正确性。激励相容定价机制的研究将促进分布式可再生能源并网,从而推动电力系统向清洁、高效和智能的目标转型与升级。 | 王宣元 高峰 康重庆 黎灿兵 刘乾 韩颖慧 Chien-Ning Yu Le Xie Gerald Sheble 宋永华 | 2019 | 电网技术2019，0，10： | 20 |
| 2 | Expression levels ofβcatenin and galectin-3 in meningioma and their effect on brain invasion and recurrence:a tissue microarray study显示文摘Objective:Meningiomas are neoplasms that arise from the meninges of the central nervous system(CNS).They constitute about25.6%of CNS tumors diagnosed in Egypt.Some morphological variants of meningiomas display aggressive behavior,leading to brain-invasive growth pattern.Although meningiomas are usually treated by complete surgical excision,the risk of postoperative recurrence remains.Hence,additional biomarkers for predicting aggressive behavior must be discovered.This study aims to explore the clinical and biological relevance of the protein expression levels ofβ-catenin and galectine-3 in meningioma and to understand the pathobiology of this neoplasm.Methods:This retrospective study was carried out on 153 cases of meningioma by using tissue microarrays and immunohistochemistry forβ-catenin and galectine-3.Results:Highβ-catenin expression was significantly associated with transitional and meningiotheliomatous meningiomas,low tumor grade,low recurrence rate,and low incidence of brain invasion.Meanwhile,high galectin-3 expression was associated with brain invasion,recurrence,high tumor grade,and tumor type.Logistic regression analysis indicated that among all variables included in the model,β-catenin and galactin-3 expression levels were significant predictors of tumor recurrence(P<0.001).Conclusions:Galectin-3 andβ-catenin are involved in meningioma recurrence but not in brain invasion.These molecules could be important potential therapeutic targets and predictors for meningiomas. | Rehab Allah Ahmed Abdelhadi M Shebl Hany Onsy Habashy | 2017 | Cancer Biology & Medicine2017，14，3： | 4 |
| 3 | Transpressive Structures in the Ghadir Shear Belt, Eastern Desert, Egypt: Evidence for Partitioning of Oblique Convergence in the Arabian-Nubian Shield during Gondwana Agglutination显示文摘Transpressional deformation has played an important role in the late Neoproterozoic evolution of the ArabianNubian Shield including the Central Eastern Desert of Egypt.The Ghadir Shear Belt is a 35 km-long,NW-oriented brittleductile shear zone that underwent overall sinistral transpression during the Late Neoproterozoic.Within this shear belt,strain is highly partitioned into shortening,oblique,extensional and strike-slip structures at multiple scales.Moreover,strain partitioning is heterogeneous along-strike giving rise to three distinct structural domains.In the East Ghadir and Ambaut shear belts,the strain is pure-shear dominated whereas the narrow sectors parallel to the shear walls in the West Ghadir Shear Zone are simple-shear dominated.These domains are comparable to splay-dominated and thrust-dominated strike-slip shear zones.The kinematic transition along the Ghadir shear belt is consistent with separate strike-slip and thrustsense shear zones.The earlier fabric(S1),is locally recognized in low strain areas and SW-ward thrusts.S2 is associated with a shallowly plunging stretching lineation(L2),and defines^NW-SE major upright macroscopic folds in the East Ghadir shear belt.F2 folds are superimposed by^NNW–SSE tight-minor and major F3 folds that are kinematically compatible with sinistral transpressional deformation along the West Ghadir Shear Zone and may represent strain partitioning during deformation.F2 and F3 folds are superimposed by ENE–WSW gentle F4 folds in the Ambaut shear belt.The sub-parallelism of F3 and F4 fold axes with the shear zones may have resulted from strain partitioning associated with simple shear deformation along narrow mylonite zones and pure shear-dominant deformation in fold zones.Dextral ENEstriking shear zones were subsequently active at ca.595 Ma,coeval with sinistral shearing along NW-to NNW-striking shear zones.The occurrence of upright folds and folds with vertical axes suggests that transpression plays a significant role in the tectonic evolution of the Ghadir shear belt.Oblique convergence may have been provoked by the buckling of the Hafafit gneiss-cored domes and relative rotations between its segments.Upright folds,fold with vertical axes and sinistral strike-slip shear zones developed in response to strain partitioning.The West Ghadir Shear Zone contains thrusts and strikeslip shear zones that resulted from lateral escape tectonics associated with lateral imbrication and transpression in response to oblique squeezing of the Arabian-Nubian Shield during agglutination of East and West Gondwana. | Mohamed ABD EL-WAHED Samir KAMH Mahmoud ASHMAWY Aly SHEBL | 2019 | Acta Geologica Sinica(English Edition)2019，93，6： | 3 |
| 4 | Aspartate transaminase to platelet ratio index in hepatitis C virus and Schistosomiasis coinfection显示文摘AIM: To assess the diagnostic accuracy,of aminotransferase-to-platelet ratio index(APRI) alone and with antischistosomal antibody(Ab) in patients with hepatitis C virus(HCV) and schistosomiasis coinfection. METHODS: This retrospective study included medical records of three hundred and eighty three Egyptianmen patients who had undergone percutaneous liver biopsy between January 2006 to April 2014 in tertiary care hospital in Qatar for diagnosis or monitoring purpose were selected. Data of patients > 18 years of age were included in the study. The values of HCV RNA titer and antischistosomal antibody titer were also taken into consideration. Patients were excluded from the study if they had any other concomitant chronic liver disease,including; history of previous antiviral or interferon therapy,immunosuppressive,therapy,chronic hepatitis B infection,human immunodeficiency virus co-infection,autoimmune hepatitis,decompensated liver disease,hepatocellular carcinoma,prior liver transplantation,and if no data about the liver biopsy present. RESULTS: Median age of patients was 46 years. About 7.1% had no fibrosis,whereas 30.4%,37.5%,20.4%,and 4.6% had fibrosis of stage Ⅰ,Ⅱ,Ⅲ,and Ⅳ respectively. In bivariate analysis,APRI score,levels of AST,platelet count and age of patient showed statistically significant association with liver fibrosis(P < 0.0001); whereas antischistosomal antibody titer(P = 0.52) and HCV RNA titer(P = 0.79) failed to show a significant association. The respective AUC values for no fibrosis,significant fibrosis,severe fibrosis and cirrhosis of APRI score were 63%,73.2%,81.1% and 88.9% respectively. This showed good sensitivity and specificity of APRI alone for grading of liver fibrosis. But the inclusion of anti-Schistosoma antibody did not improve the prediction of fibrosis stage. CONCLUSION: The study results suggest that noninvasive biochemical markers like APRI are sensitive and specific in diagnosing the degree of fibrosis and cirrhosis in patients with coinfection of HCV and schistosomiasis as compared to biopsy. The addition of antischistosomal Ab to APRI did not improve sensitivity for predicting the degree of cirrhosis. | Moutaz Derbala Mohammed Elshiekh Elbadri Aliaa Mohamed Amer Saad Al Kaabi Khaleel Hassan Sultan Yasser Medhat Kamel Eman Hassan Satti Elsayed Tony Yervant Avades Prem Chandra Fatma M Shebl | 2015 | World Journal of Gastroenterology2015，21，46： | 2 |
| 5 | Interleukin-28 and hepatitis C virus genotype-4:Treatment-induced clearance and liver fibrosis显示文摘AIM:To investigate the association between interleukin-28B(IL28B) genotype and response to treatment and hepatic fibrosis in patients with hepatitis C virus(HCV) genotype 4.METHODS:Two hundred and one HCV-genotype 4 patients were included.All patients were treated with Peginterferon alph2a/Ribavirin for 48 wk.End of treatment response(ETR) was defined as loss of detectable serum HCV RNA at the end of treatment.Sustained viral response(SVR) was defined as loss of detectable serum HCV RNA at the end of 24 wk follow up.Genotyping of IL28B rs12979860 was performed using the TaqMan assay.We used logistic regression to estimate the adjusted odds ratio(aOR) and 95%CI.RESULTS:The study included 201 HCV-genotype 4 patients.The majority of patients were men(89.6%),with a median age of 47 years,inter-quartile range(40-51).Approximately 62.5% of patients had ETR,and 49.6% had SVR.Individuals who achieved SVR were more likely to be younger(χ 2 = 4.91,P = 0.027),and less likely to have fibrosis(χ 2 = 15.54,P < 0.0001),or inflammation(χ 2 = 7.58,P = 0.006).The genotype distribution of rs12979860 was 36.2%,49.0% and 14.8% for genotypes CC,CT,and TT,respectively.In these participants,rs12979860 genotype distribution did not differ by gender(P = 0.466),pretreatment viral load(P = 0.600),inflammation(P = 0.435),or fibrosis(P = 0.291).The frequencies of IL28B rs12979860 genotypes were TT(14.8%),CT(49.0%),and CC(36.2%).Compared to rs12979860 genotype TT,aORs(95%CI) for ETR and SVR were:CC genotype,[17.55(5.34-57.69) and 5.92(2.09-16.76),respectively];CT genotype,[5.15(1.80-14.78) and 2.48(0.94-6.52),respectively].In the current study,the patients who did not achieve ETR or SVR had a lower prevalence of rs12979860 CC(17.4% and 23.3%,respectively) than individuals who had ETR or SVR(47.9% and 47.2%,respectively).Individuals with rs12979860 CC genotype had approximately 6 times the odds of SVR compared to individuals with TT genotype(aOR = 5.92;95%CI:2.09-16.76).Similarly,patients with CT genotype had SVR more often than patients with TT genotype(aOR = 2.48;95%CI:0.94-6.52).Carrying at least one copy of the C allele(genotypes CT and CC) had almost 8 times the probability of ETR compared to those with genotype rs12979860 TT(aOR = 7.87;95%CI:2.84-21.82),and approximately 3 times the odds of SVR compared to those with genotype rs12979860 TT(aOR = 3.46;95%CI:1.37-8.74).In addition,data were consistent with a significant gene-dose relationship(aOR = 4.05/allele;95%CI:2.27-7.22).The association between rs12979860 genotype and SVR was similar among those who achieved and those who did not achieve SVR.CONCLUSION:In HCV-genotype 4 patients,rs12979860 is a sensitive predictor of viral clearance,independent of viral load,age,gender or fibrosis,with no similar relation to severity of fibrosis. | Moutaz Derbala Nasser Rizk Fatima Shebl Saad Alkaabi Nazeeh Eldweik Anil John Manik Sharma Rafie Yaqoob Muneera Almohanadi Mohammed Butt Khaled Alejji | 2012 | World Journal of Gastroenterology2012，18，47： | 2 |
| 6 | Application of auction as a price mechanism for the interchange of electric power显示文摘 | Post D L Coppinger S S Sheble G B | 1995 | IEEE Transactions on Power System1995，10，3： | 2 |
| 7 | Structures and formulations for electric power auctions显示文摘 | Dekrajangpetch S Sheble G B | 2000 | Electric Power System Research2000，，54： | 2 |
| 8 | Application of auction as a pricing mechanism for the interchange of electric power 显示文摘 | Post D L Coppinger S S Sheble G B | 1995 | 1EEE Transactions on Power Systems1995，10，3： | 1 |
| 9 | A new approach to AC/DC power flow显示文摘 | Smed T Andersson G Sheble G B | 1991 | IEEE Transactions on Power Systems1991，6，3： | 1 |
| 10 | Interior-point linear programming algorithm for auction methods显示文摘 | Dekrajangpetch S Sheble G B | 2000 | IEEE Transactions on Power Systems2000，15，2： | 1 |
| 11 | Genetic algorithm solution of economic dispatch with valve point loading显示文摘 | WALTERS D C SHEBLE G B | 1993 | IEEE Transactions on Power Systems1993，8，3： | 1 |
| 12 | A profit-based unit commitment GA for the competitive environment显示文摘 | Richter C W Sheble G B | 2002 | IEEE Transactions on Power Systems2002，15，2： | 1 |
| 13 | Genetic algorithm solution of economic dispatch with valve point loading显示文摘 | Walters D C Sheble G B | 1993 | IEEE Trans on Power Systems1993，8，3： | 1 |
| 14 | Unit commitment literature synopsis显示文摘 | Sheble G B Fahd G N | 1994 | IEEE Trans on Power Systems1994，9，1： | 1 |
| 15 | A profit-based unit commitment GA for the competitive environment显示文摘 | RICHTER C W SHEBLE G B | 2000 | IEEE Transaction on Power Systems2000，15，2： | 1 |
| 16 | Evaluation of dynamic programming based methods and multiple area representation for thermal unit commitment显示文摘 | Pang C K Sheble G B Albuyeh F | 1981 | IEEE Trans on Power Apparatus and Systems1981，100，3： | 1 |
| 17 | A new approach to AC/DC power flow显示文摘 | Smed T Andersson G Sheble G B | 1991 | IEEE Transactions on Power Systems1991，6，3： | 1 |
| 18 | Genetic algorithm solution of economic dispatch with valve point loading显示文摘 | David C Walters Gerald B Sheble | 1993 | IEEE Trans on Power System1993，8，3： | 1 |
| 19 | Genetic algorithm evolution of utility bidding strategies of the competitive market place-power systems显示文摘 | Richter C W Sheble G B | 1998 | IEEE Trans onPower Systems1998，13，1： | 1 |
| 20 | Redox reactions in hydrocarbon clastic reservoirs : Experimental validation of this mechanism for porosity enhancement 显示文摘 | Shebl M A Surdam R C | 1996 | Chemical Geology1996，132，： | 1 |
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