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| 1 | Characterization of focal liver lesions with SonoVue~-enhanced sonography: International multicenter-study in comparison to CT and MRI显示文摘AIM: To evaluate in a multicenter study whether the sonographic characterization of focal liver lesions can be improved using SonoVueüà-enhancement; and to compare this method with computed tomography (CT) and magnetic resonance imaging (MRI). METHODS: One hundred and thirty four patients with one focal liver lesion detected in baseline ultrasound (US) were examined with conventional US, contrastenhanced US (n = 134), contrast-enhanced CT (n = 115) and/or dynamic contrast-enhanced MRI (n = 70). The lesions were classified as malignant, benign or indeterminate and the type of lesion was determined. The f inal diagnosis based on the combined information of all imaging examinations, clinical information and histology (n = 32) was used. Comparisons were made to see whether the addition of contrast-enhanced US led to the improvement of the characterization of doubtful focal liver lesions. RESULTS: In comparison with unenhanced US, SonoVue markedly improves sensitivity and specificity for the characterization (malignant/benign) of focal liver lesions. In comparison with CT and/or dynamic MRI, SonoVueüà -enhanced sonography applied for characterization of focal liver lesions was 30.2% more sensitive in the recognition of malignancy and 16.1% more specific in the exclusion of malignancy and overall 22.9% more accurate. In the subgroup with confirmative histology available (n = 30), sensitivity was 95.5% (CEUS), 72.2% (CT) and 81.8% (MRI), and specif icity was 75.0% (CEUS), 37.5% (CT) and 42.9% (MRI). The sensitivity and specif icity of CEUS for the identif ication of focal nodular hyperplasia (FNH) and hemangiomas was 100% and 87%, resulting in an accuracy of 94.5%. CONCLUSION: SonoVueüà-enhanced sonography emerges as the most sensitive, most specif ic and thus most accurate imaging modality for the characterization of focal liver lesions. | Hervé Trillaud Jean-Michel Bruel Pierre-Jean Valette Valérie Vilgrain Gérard Schmutz Raymond Oyen Wieslaw Jakubowski Jan Danes Vlastimil Valek Christian Greis | 2009 | World Journal of Gastroenterology2009，15，30： | 34 |
| 2 | 电力市场条件下的工业负荷管理显示文摘讨论了竞争性电力市场的模式以及电价在竞争性电力市场中的波动性 ;论述了竞争性电力市场中的工业电力终端用户与电力供应商之间可能签订的合同 ;以某国的工业负荷 GISA SA为案例 ,分析了在竞争的电力市场中 ,电力用户为了避免或减少风险 。 | 谢传胜 Alain Schmutz Dr.Edgard Gnansounou Pro.Gerassim os Sarlos | 2001 | 现代电力2001，18，3： | 2 |
| 3 | Physical mapping of SOD1 to bovine chromosome 1显示文摘 | SCHMUTZ S M CORNWELL D MOKER J S | 1996 | Cytogenetics and Cell Genetics1996，72，1： | 1 |
| 4 | The chordae willisii in the superior sagittal sinus:morphology and classification显示文摘 | Schmutz HK | 1980 | Acta Anat1980，108，： | 1 |
| 5 | Caffeic acid and glycerol are constituents of the suberin layers in green cotton fibers显示文摘 | Schmutz A Jenny T Amrhein N | 1993 | Planta1993，189，3： | 1 |
| 6 | The effect of sodium-n-dipropyl acetate on gamma-aminobutyric acid-dependent inhibition in the rat cortex and substantia nigra in relation to its anticonvulsant activity 显示文摘 | Kerwin RW Olpe HR Schmutz M | 1980 | Br Pharmacol1980，71，： | 1 |
| 7 | A form of albinism in cattle is caused by a tyrosinase frameshift mutation显示文摘 | Sheila M Schmutz Tom G Berryere Daniel C Ciobanu | 2004 | Mammalian Genome2004，15，： | 1 |
| 8 | Assessment ofTREM2 rs75932628 association with Alzheimer's disease in apopulation -based sample : the cache county study 显示文摘 | Gonzalez Murcia JD Schmutz C Munger C | 2013 | NeurobiolAging2013，34，12： | 1 |
| 9 | Evaluation of the na- no-oligosaccharide factor lipido-colloid matrix in the local management of venous leg ulcers : results of a randomised, con- trolled trial显示文摘 | Schmutz JL Meanme S Fays S | 2008 | Int Wound J2008，5，2： | 1 |
| 10 | Mono- cytes/macrophages express chemokine receptor CCR9 in rheumatoid arthritis and CCL25 stimulates their differenti- ation显示文摘 | Schmutz C Cartwright A Williams H | 2010 | Arthritis Res Ther2010，12，4： | 1 |
| 11 | Cumulative effects of land use on fish metrics in different types of running waters in Austria显示文摘 | TRAUTWEIN C SCHINEGGER R SCHMUTZ S | 2012 | Aquatic Sciences2012，74，2： | 1 |
| 12 | A One-dimensional Ensemble Forecast and Assimilation System for Fog Prediction显示文摘 | M. D. Müller C. Schmutz E. Parlow | 2007 | Pure and Applied Geophysics (-)2007，，6： | 1 |
| 13 | Materials' effects on the elevated and room temperature performance of C/LiMn2O4Li -ion batteries显示文摘 | Amatucci G G Schmutz C N | 1997 | J Power Sources1997，69，： | 1 |
| 14 | Impedance characterization and modeling of electrodes for biomedical applications显示文摘 | Franks W Schenker I Schmutz | 2005 | IEEE Transactions on Biomedical Engineering2005，52，7： | 1 |
| 15 | Zur Chemie und Pharmakologie von in 10-Stellung basisch substituierten 5-Dibenzo- diazepin-Derivaten 显示文摘 | Hunziker F Lauener H Schmutz J | 1963 | Arzneimittel- Forsch1963，13，： | 1 |
| 16 | Locally Addressable Elec- trochemical Patterning Technique (LAEPT) applied to ,poly( L-ly-sine) -graft-poly( ethylene glycol) adlayers on titanium and silicon oxide surfaces显示文摘 | Tang CS Schmutz P Petronis S | 2005 | Biotechnol Bioeng2005，91，3： | 1 |
| 17 | Hyperbaric oxygen therapy in the treatment of radio - induced lesions in normal tissues:a literature revlew显示文摘 | Pasquier D Hoelscher T Schmutz J | 2004 | Radiotherapy and Oncology2004，72，1： | 1 |
| 18 | Genome sequence ofthe palaeopolyploid soybean显示文摘 | Schmutz J Cannon S B Schlueter J | 2010 | Nature2010，463，7278： | 1 |
| 19 | Small bowel obstruction:role and contribution of sonography显示文摘 | Schmutz GR Benko A Fournier L | 1997 | Eur Radiol1997，7，： | 1 |
| 20 | Genome sequence ofthe paleopolyploid soybean显示文摘 | Schmutz J Cannon S B Schlueter J | 2010 | Nature2010，463，： | 1 |
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