|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Near-infrared fluorescence sentinel lymph node detection in gastric cancer: A pilot study显示文摘AIM: To investigate feasibility and accuracy of nearinfrared fluorescence imaging using indocyanine green: nanocolloid for sentinel lymph node(SLN) detection in gastric cancer.METHODS: A prospective, single-institution, phaseI feasibility trial was conducted. Patients suffering from gastric cancer and planned for gastrectomy were included. During surgery, a subserosal injection of 1.6 m L ICG:Nanocoll was administered around the tumor. NIR fluorescence imaging of the abdominal cavity was performed using the Mini-FLARE? NIR fluorescence imaging system. Lymphatic pathways and SLNs were visualized. Of every detected SLN, the corresponding lymph node station, signal-to-background ratio and histopathological diagnosis was determined. Patients underwent standard-of-care gastrectomy. Detected SLNs outside the standard dissection planes were also resected and evaluated.RESULTS: Twenty-six patients were enrolled. Four patients were excluded because distant metastases were found during surgery or due to technical failure of the injection. In 21 of the remaining 22 patients, at least 1 SLN was detected by NIR Fluorescence imaging(mean 3.1 SLNs; range 1-6). In 8 of the 21 patients, tumor-positive LNs were found. Overall accuracy of the technique was 90%(70%-99%; 95%CI), which decreased by higher p T-stage(100%, 100%, 100%, 90%, 0% for respectively Tx, T1, T2, T3, T4 tumors). All NIR-negative SLNs were completely effaced by tumor. Mean fluorescence signal-to-background ratio of SLNs was 4.4(range 1.4-19.8). In 8 of the 21 patients, SLNs outside the standard resection plane were identified, that contained malignant cells in 2 patients.CONCLUSION: This study shows successful use of ICG:Nanocoll as lymphatic tracer for SLN detection in gastric cancer. Moreover, tumor-containing LNs outside the standard dissection planes were identified. | Quirijn RJG Tummers Leonora SF Boogerd Wobbe O de Steur Floris PR Verbeek Martin C Boonstra Henricus JM Handgraaf John V Frangioni Cornelis JH van de Velde Henk H Hartgrink Alexander L Vahrmeijer | 2016 | World Journal of Gastroenterology2016，22，13： | 9 |
| 2 | Pulmonary infection control window in treatment of severe respiratory failure of chronic obstructive pulmonary diseases: a prospective, randomized controlled, multi-centred study显示文摘Background Early withdraw from invasive mechanical ventilation (MV) followed by noninvasive MV is a new strategy for changing modes of treatment. This study was conducted to estimate the feasibility and the efficacy of early extubation and sequential noninvasive MV commenced at beginning of pulmonary infection control window in patients with exacerbated hypercapnic respiratory failure caused by chronic obstructive pulmonary diseases (COPD). Methods A prospective, randomized controlled study was conducted in eleven teaching hospitals' respiratory or medical intensive care units in China. Ninety intubated COPD patients with severe hypercapnic respiratory failure triggered by pulmonary infection (pneumonia or purulent bronchitis) were involved in the study. When the pulmonary infection had been controlled by antibiotics and comprehensive therapy, the 'pulmonary infection control window (PIC window)' has been reached. Each case was randomly assigned to study group (extubation and noninvasive MV via facial mask immediately) or control group (invasive MV was received continuously after PIC window by using conventional weaning technique).Results Study group (n=47) and control group (n=43) had similar clinical characteristics initially and at the time of PIC window. Compared with control group, study group had shorter duration of invasive MV [(6.4±4.4) days vs (11.3±6.2) days, P=0.000], lower rate of ventilator associated pneumonia (VAP) (3/47 vs 12/43, P=0.014), fewer days in ICU [(12±8) days vs (16±11) days, P=0.047] and lower hospital mortality (1/47 vs 7/43, P=0.025).Conclusions In COPD patients requiring intubation and invasive MV for hypercapnic respiratory failure, which is exacerbated by pulmonary infection, early extubation followed by noninvasive MV initiated at the start of PIC window may decrease significantly the duration of invasive MV, the risk of VAP and hospital mortality. | Wang, C Zhan, QY Cao, ZX Wei, LQ Cheng, ZZ Liu, S Zhang, JL Chen, RC Luo, Q Niu, SF Zhu, L Wu, DW Fang, BM Wu, TH Wang, CZ Liu, YN | 2005 | Chinese Medical Journal2005，，19： | 6 |
| 3 | Randomised trial of 'slow' versus 'fast' feed advancements on the incidence of necrotising enterocolisis in very low birth weight infants显示文摘 | Ambalavanan N Wright L | 1999 | J Pediatr1999，134，： | 1 |
| 4 | Knowledge, attitudes and practices (KAP) related to the pandemic (H1N1)2009 among Chinese general population:a telephone survey 显示文摘 | Lin Y Huang L Nie SF | 2011 | BMC Infectious Dis- eases2011，11，： | 1 |
| 5 | Emulsifying propertyof whey peptide fractions as a function of pH and IonicStrength显示文摘 | Turgeon S L Cauthier SF Paqu in P | 1992 | Food Sci1992，57，60： | 1 |
| 6 | Haemodynamic insights into the effects of is- chaemia and cycle length on tissue Doppler derived mitral annulus diastolic ve- locities 显示文摘 | Nagueh SF Rao L Solo J | 2004 | J Clin Sci (Lond)2004，106，2： | 1 |
| 7 | The consensus concept for thermostability engineering of proteins 显示文摘 | Lehmann M Pasamontes L Lassen SF Wyss M | 2000 | Biochimica et Biophysica Acta (BBA) -Protein Structure and Molecular Enzy- mology2000，1543，2： | 1 |
| 8 | HER2/neu expression correlates with vascular endothelial growth factor-C and lymphangiogenesis in lymph node-positive breast cancer显示文摘 | Schoppmann SF Tamandl D Roberts L | 2010 | Ann Oncol2010，21，5： | 1 |
| 9 | LCN6, a novel human epididyrnal lipocalin 显示文摘 | Katherine GH Qiang L Frank SF | 2003 | Reprod Biol Endo2003，1，： | 1 |
| 10 | Overexpression of Pokemon in non-small cell lung cancer and foreshowing tumor biological behavior as well as clinical results 显示文摘 | Zhao ZH Wang SF Yu L | 2008 | Lung Cancer2008，62，1： | 1 |
| 11 | Medium chain acyl-CoA dehydrogenase(MCAD)mutations identified by MS/MS-based prospective screening of newborns differ from those observed in patients with clinical symptoms:identification and characterization of a new,prevalent mutation that result in mild MCAD deficiency显示文摘 | Andresen BS Dobrowolski SF O'Reilly L | 2001 | Am J Hum Genet2001，68，6： | 1 |
| 12 | Grape polyphenols inhibit Akt/mammalian target of rapamycin signaling and potentiate the effects of gefitinib in breast cancer显示文摘 | Castillo-pichardo L Dharmawardhane SF | 2012 | Nutr Cancer2012，64，7： | 1 |
| 13 | Reliability,Validity,clinical utility of the research diagnostic crpressio,non - spe-cific physical symptoms and graded chronic pain 显示文摘 | Dworkin SF Sherman J Mancl L | 2002 | J OrfacPain2002，16，3： | 1 |
| 14 | Molec-ular methods for the identification of Aspergillus species显示文摘 | Hinrikson HP Hurst SF de Aguirre L | 2005 | Med Mycol2005，43，1： | 1 |
| 15 | Muhicenter evaluation of a new screening test that detects Clostridium difficile in fecal speci- mens显示文摘 | Zheng L Keller SF Lyerly DM | 2004 | J Clin Microbiol2004，42，8： | 1 |
| 16 | Purification and identification of the STAT5 protease in myeloid cells显示文摘 | Schuster B Hendry L Byers H Lynham SF Ward MA John S | 2007 | Biochem J2007，404，： | 1 |
| 17 | Elevated Soluble vegf receptor stir-1 correlates with endothelial injury in iga nephropathy显示文摘 | Zhai YL Zhu L Shi SF | 2014 | PLoS One2014，9，10： | 1 |
| 18 | Polymorphisms in PLIN and hypertension combined with obesity and lipid profiles in Han Chinese 显示文摘 | YAN W L CHEN SF HUANGJ F | 2004 | Obesity Research2004，12，： | 1 |
| 19 | Phenotypic features, androgen receptor binding, and mutational analysis in 278 clinical cases reported as androgen insensitivity syndrome显示文摘 | Ahmed SF Cheng A Dovey L | 2000 | J Clin Endocrinol Metab2000，85，2： | 1 |
| 20 | Effect of intravenously injected zinc on tissue zinc and metallothionein gene expression ofbroilers显示文摘 | Shen SF Wang RL Lu L | 2013 | Br Poult Sci2013，54，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员