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| 1 | Seismic response evaluation of base-isolated reinforced concrete buildings under bidirectional excitation显示文摘This paper reports on an investigation of the seismic response of base-isolated reinforced concrete buildings,which considers various isolation system parameters under bidirectional near-fault and far-fault motions. Three-dimensional models of 4-, 8-, and 12-story base-isolated buildings with nonlinear effects in the isolation system and the superstructure are investigated, and nonlinear response history analysis is carried out. The bounding values of isolation system properties that incorporate the aging effect of isolators are also taken into account, as is the current state of practice in the design and analysis of base-isolated buildings. The response indicators of the buildings are studied for near-fault and far-fault motions weight-scaled to represent the design earthquake(DE) level and the risk-targeted maximum considered earthquake(MCER)level. Results of the nonlinear response history analyses indicate no structural damage under DE-level motions for near-fault and far-fault motions and for MCER-level far-fault motions, whereas minor structural damage is observed under MCERlevel near-fault motions. Results of the base-isolated buildings are compared with their fixed-base counterparts. Significant reduction of the superstructure response of the 12-story base-isolated building compared to the fixed-base condition indicates that base isolation can be effectively used in taller buildings to enhance performance. Additionally, the applicability of a rigid superstructure to predict the isolator displacement demand is also investigated. It is found that the isolator displacements can be estimated accurately using a rigid body model for the superstructure for the buildings considered. | Satish Bhagat Anil C Wijeyewickrema | 2017 | Earthquake Engineering and Engineering Vibration2017，16，2： | 8 |
| 2 | Primary squamous cell carcinoma of the rectum: An update and implications for treatment显示文摘AIM: To provide an update on the aetiology, pathogenesis, diagnosis, staging and management of rectal squamous cell carcinoma(SCC).METHODS: A systematic review was conducted according to the preferred reporting items for Systematic Reviews and Meta-Analyses guidelines. A comprehensive search of Ovid MEDLINE was performed with the reference list of selected articles reviewed to ensure all relevant publications were captured. The search strategy was limited to the English language, spanning from 1946 to 2015. A qualitative analysis was undertaken examining patient demographics, clinical presentation, diagnosis, staging, treatment and outcome. The quantitaive analysis was limited to data extracted on treatment and outcomes including radiological, clinical and pathological complete response where available. The narrative and quantitative review were synthesised in concert.RESULTS: The search identified 487 articles in total with 79 included in the qualitative review. The quantitative analysis involved 63 articles, consisting of 43 case reports and 20 case series with a total of 142 individual cases. The underlying pathogenesis of rectal SCC while unclear, continues to be defined, with increasing evidence of a metaplasia-dysplasia-carcinoma sequence and a possible role for human papilloma virus in this progression. The presentation is similar to rectal adenocarcinoma, with a diagnosis confirmed by endoscopic biopsy. Many presumed rectal SCC's are in fact an extension of an anal SCC, and cytokeratin markers are a useful adjunct in this distinction. Staging is most accurately reflected by the tumour-nodemetastasis classification for rectal adenocarcinoma. It involves examining locoregional disease by way of magnetic resonance imaging and/or endorectal ultrasound, with systemic spread excluded by way of computed tomography. Positron emission tomography is integral in the workup to exclude an external siteof primary SCC with metastasis to the rectum. While the optimal treatment remains as yet undefined, recent studies have demonstrated a global shift away from surgery towards definitive chemoradiotherapy as primary treatment. Pooled overall survival was calculated to be 86% in patients managed with chemoradiation compared with 48% for those treated traditionally with surgery. Furthermore, local recurrence and metastatic rates were 25% vs 10% and 30% vs 13% for the chemoradiation vs conventional treatment cohorts.CONCLUSION: The changing paradigm in the treatment of rectal SCC holds great promise for improved outcomes in this rare disease. | Glen R Guerra Cherng H Kong Satish K Warrier Andrew C Lynch Alexander G Heriot Samuel Y Ngan | 2016 | World Journal of Gastrointestinal Surgery2016，8，3： | 5 |
| 3 | Land Application of Sugar Beet By-products: Effects on Runoff and Percolating Water Ouality显示文摘 | Kumar Kuldip Rosen Carl J Satish C Gupta | 2009 | Journal of environmental quality2009，38，1： | 1 |
| 4 | On the Re-strictor Design Parameter of Hybrid Journal Bearing forOptimum Rotor Dynamic Coefficients显示文摘 | Kumar Vijay Sharma Satish C Jain S C | 2006 | TribologyInternational2006，39，4： | 1 |
| 5 | Chaos based spread spectrum image steganography显示文摘 | Satish K Jayakar T Tobin C | 2004 | IEEE Transactions on Consumer Electronics2004，50，2： | 1 |
| 6 | Synthesis and characterization of pH-sensitive hydrogel composed of carboxymethyl chitosan for colon targeted delivery of ornidazole 显示文摘 | Vaghani S S Patel M M Satish C S | 2012 | Carbohydr Res2012，347，1： | 1 |
| 7 | Effect of short glass fibers on the mechanical properties of cast ZA27 alloy composites 显示文摘 | SHARMA S C SEAH K H W SATISH M GIRISH B M | 1996 | Materials and Design1996，17，： | 1 |
| 8 | Physical Modeling of the Flow Modifier on the Dynamics of Molten Steel Flowing in a Tundish 显示文摘 | SATISH C KORIA | 1994 | ISIJ International1994，34，10： | 1 |
| 9 | Five-bar motion and path generators with variable topology for motion between extreme positions 显示文摘 | Balli S S Satish C | 2002 | Mechanism and Machine Theory2002，37，11： | 1 |
| 10 | On the Restrictor Design Parameter of Hybrid Journal Bearing for Optimum Rotordynamic Coefficients 显示文摘 | Kumar Vijay Sharma Satish C Jain S C | 2006 | Tribology International2006，39，4： | 1 |
| 11 | Mechanical properties and fractography of zircon-particle-reinforced ZA-27 alloy composite materials 显示文摘 | SHARMA S C GIRISH B M SOMASHEKAR D R KAMATH R SATISH B M | 1999 | Composite Science and Technology1999，59，： | 1 |
| 12 | Synthesis and characterization of pH-sensitive hydrogel composed of carboxymethyl chitosan for colon targeted delivery of ornidazole显示文摘 | Vaghani S S Patel M M Satish C S | 2012 | Carbohydrate Research2012，347，1： | 1 |
| 13 | Sliding wear behavior of zircon particles reinforced ZA-27 alloy composite materials 显示文摘 | SHARMA S C GIRISH B M SOMASHEKAR D R SATISH B M KAMATH R | 1999 | Wear1999，224，： | 1 |
| 14 | Synthesis and charac- terization of pH-sensitive hydrogel composed of carbo~y methyl chitosan for colon targeted delivery of ornidazole显示文摘 | Vaghani S S Patel M M Satish C S | 2012 | Carbohvdr Res2012，347，1： | 1 |
| 15 | Effect of SiC particle reinforcement on the unlubricated sliding wear behavior of ZA-27 alloy composites 显示文摘 | SHARMA S C GIRISH B M KAMATH R SATISH B M | 1997 | Wear1997，213，： | 1 |
| 16 | Y-junction carbon nanotubes显示文摘 | SATISH KUMAR B C THOMAS P J GOVINDARAJ A RAO C N R | 2000 | Appl Phys Lett2000，77，： | 1 |
| 17 | Performance of membrane compensated multirecess hydrostatic/hybrid flexible journal bearing system considering various recess shapes显示文摘 | Narendra Singh Satish C Sharma | 2004 | Tribology International2004，37，： | 1 |
| 18 | Maternal and fetal outcome of gestational diabetes显示文摘 | Mohamed S Kaler M Satish C | 2012 | Arch Child Fetal Neonatal Ed2012，97，： | 1 |
| 19 | Effect of short glass fibers on the mechanical properties of cast ZA27 alloy composites显示文摘 | Sharma S C Seah K H W Satish B M | 1996 | Materials & Design1996，17，5： | 1 |
| 20 | Performanceanalysis of a multirecess capillary compensated conicalhydrostatic journal bearing显示文摘 | Sharma Satish C Phalle Vikas M Jain S C | 2011 | Tribology International2011，，44： | 1 |
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