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	题名	作者	年代	出处	被引量
1	Bile acids as drivers and biomarkers of hepatocellular carcinoma显示文摘The prevalence of hepatocellular carcinoma(HCC)is rapidly increasing,driven not least in part by the escalating prevalence of non-alcoholic fatty liver disease.Bile acid(BA)profiles are altered in patients with HCC and there is a developing body of evidence from in vitro human cellular models as well as rodent data suggesting that BA are able to modulate fundamental processes that impact on cellular phenotype predisposing to the development of HCC including senescence,proliferation and epithelial-mesenchymal transition.Changes in BA profiles associated with HCC have the potential to be exploited clinically.Whilst excellent diagnostic and imaging tools are available,their use to screen populations with advanced liver disease at risk of HCC is limited by high cost and low availability.The mainstay for HCC screening among subjects with cirrhosis remains frequent interval ultrasound scanning.Importantly,currently available serum biomarkers add little to diagnostic accuracy.Here,we review the current literature on the use of BA measurements as predictors of HCC incidence in addition to their use as a potential screening method for the early detection of HCC.Whilst these approaches do show early promise,there are limitations including the relatively small cohort sizes,the lack of a standardized approach to BA measurement,and the use of inappropriate control comparator samples.	Santo Colosimo Jeremy W Tomlinson	2022	World Journal of Hepatology2022，14，9：	2
2	Effect of prepartum dietary protein level on performance of primigravid and multiparous holstein dairy cows显示文摘	Santos J E P DePeters E J Jardon P W	2001	J Dairy Sei2001，84，：	1
3	Incidence and outcomes of spinal cord injury clinical syndromes显示文摘	McKinley W Santos K Meade M	2007	J Spinal Cord Med2007，30，3：	1
4	Partially acetylated chitosan oligo and polymers induce an oxidative burst sus- pension cultured ceils of the gymnosperm Araucaria angustifolia 显示文摘	Dos Santos A L W Gueddari E I Trombuotto S	2008	Biomacromolecules2008，9，12：	1
5	Drug resistance in Trypanosoma cruzi is not associated with amplification or overexpression of P glycoprotein ( PGP ) genes显示文摘	MURTA S M DOS SANTOS W G ANACLETO C	2001	Mol Biochem Parasitol2001，117，2：	1
6	Dynamic reprogramming of DNA methylation in the early mouse embryo 显示文摘	SANTOS F HENDRICH B REIK W	2002	Dev Biol2002，241，1：	1
7	Influence of common lambsquarters (Chenopodium album) densities and phosphorus fertilization on lettuce显示文摘	SANTOS B M DUSKY J A STALL W M	2004	Crop Protection2004，23，：	1
8	Large-area fabrication of periodic arrays of nanoholes in metal films and their application in biosensing and plasmonic-en-hanced photovoltaics显示文摘	MENEZES J W FERREIRA J SANTOS M J L	2010	Adv Funct Mater2010，20，22：	1
9	Prognostic value of FLT3 mutations among different cytogenetie subgroups in acute myeloid leukemia 显示文摘	SANTOS F P JONES D QIAO W	2011	Cancer2011，117，：	1
10	On-line system for preconcentration and determination of metals in vegetables by inductively coupled plasma optical emission spectrometry显示文摘	BEZERRA M A dos SANTOS W N L LEMOS V A	2007	Journal of Hazardous Materials2007，148，12：	1
11	Human Papaillomavirus Deoxyribonucleic Acid in Cervical Carcinoma from Primary and Metastatic Sites显示文摘	Lancaster W D Castellano C Santos C	1986	Am J Obstet Gynecol1986，154，12：	1
12	Conservation of methyl ation reprogramming in mammaIian development :aberrant re programming in cloned embryos 显示文摘	Dean W Santos F Stojkovic M	2001	Proc Natl Acad Sc USA2001，98，13：	1
13	Conservation of methylatiou reprogramming in mammalian development:aberrant reprogramming in cloned embryos显示文摘	DNEA W SANTOS F STOJKOVIC M	2001	Proc Natl Acad Sci USA2001，98，13：	1
14	Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt-dependent pathways显示文摘	Sampaio W O Souza dos Santos R A Faria-Silva R	2007	Hypertension2007，49，1：	1
15	Conservation of methylation reprogramming in mammalian development:aberrant reprogramming in cloned embryos显示文摘	Dean W Santos F Stojkovic M Zakhartchenko V Walter J Wolf E Reik W	2001	Proceedings of the National Academy of Sciences2001，98，13：	1
16	The positively charged surface of herpes simplex virus UIA2 mediates DNA binding显示文摘	KOMAZIN - MEREDITH G SANTOS W L FILMAN D J	2008	J Biol Chem2008，283，10：	1
17	Influ-ence of diet on the structure and function of the bacterial hind-gut community of crickets显示文摘	Santo Domingo J W Kaufman M G Klug M J	1998	Molecular Ecology1998，，7：	1
18	Use of RAPD to aid selection in common bean backcross breeding programs显示文摘	Hagiwara W E Santos J B Carmo S L M	2001	Crop Breeding and Applied Biotechnology2001，1，4：	1
19	Phase segregation, shearthin- ning and rheological behavior of crude oil-in-water emulsions 显示文摘	dos Santos R G Bannwart A C Loh W	2014	Chemical Engineering Research and Design2014，92，8：	1
20	Tidal pumping drives nutrient and dissolved organic matter dynamics in a Gulf of Mexico subterranean estuary 显示文摘	Santos I R Bumett W C Dittmar T	2009	Geochimica et Cosnwchimica Acta2009，73，：	1

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