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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | The analysis of fluorescent whitening agents using reversed-phase HPLC and mass spectrometry显示文摘 | Santos M D L Nerin C Domeno C | 2004 | LCGC Asia Pacific2004，7，3： | 1 |
| 3 | Agro- industrial residues as low-price feedstock for diesel- like fuel production by thermal cracking显示文摘 | Santos A L F Martins D U Iha O K | 2010 | Bioresource Technology2010，101，： | 1 |
| 4 | Compressed sensing MRI显示文摘 | LUSTIG M DONOHO D L SANTOS J M | 2008 | IEEE Signal Processing Magazine2008，25，2： | 1 |
| 5 | Evaluation of the anti-inflammatory and antioxidant activities of di-Cglucoflavones from Lychnophora ericoides (Asteraceae) 显示文摘 | Gobbo-Neto L Santos M D Kanashiro A | 2005 | Planta Med2005，71，1： | 1 |
| 6 | Diabetes and mitochondrial oxidative stress: a study using heart mitochondria from the diabetic Goto-Kakizaki rat 显示文摘 | Santos D L Palmeira C M Seica R | 2003 | Mol Cell Biochem2003，246，12： | 1 |
| 7 | Resuscitation of Escherichia coil VBNC cells depends on a variety of environmental or chemical stimuli 显示文摘 | Pinto D Almeida V Almeida Santos M Chambel L | 2011 | Appl Microbiol2011，110，6： | 1 |
| 8 | Global lower bounds for flow shops with muItiple processors 显示文摘 | Santos D L Hunsucker J L Deal D E | 1995 | European Journal of Operational Research1995，80，1： | 1 |
| 9 | Copper emission factors from intensive shrimp aquaculture显示文摘 | Lacerda L D Santos J A Madrid R M | 2006 | Marine Pollution Bulletin2006，52，12： | 1 |
| 10 | Small strain viscoelastic behaviour of wheat gluten-pentosan mixtures 显示文摘 | Santos D M J Monteiro S R Da Silva J A L | 2005 | Eur Food Res Technol2005，，221： | 1 |
| 11 | An improved har- mony search algorithm for synchronization of discrete-time chaotic systems 显示文摘 | Santos Coelho L d de Andrade Bernert D L | 2009 | Chaos Solitons and Fractals2009，41，15： | 1 |
| 12 | Long-lasting neuro- pathic pain induced by brachial plexus injury in mice:Role triggered by pro-inflammatory cytokine,tumor necrosis factor α 显示文摘 | Quintao N L M Balz D Santos A R S | 2006 | Neuropharmacology2006，50，5： | 1 |
| 13 | Psoriatic arthritis: a clinical entity distinct from psoriasis? 显示文摘 | Ruiz D G Azevedo M N Santos O L | 2012 | Rev Bras Reumatol2012，52，4： | 1 |
| 14 | Carvedilol protects against doxorubicin -induced mitochondrial cardiomyopathy显示文摘 | Santos D L Moreno A J Leino R L | | 0，，03： | 1 |
| 15 | Evaluation of the effects of two Lactobacillus buchneri strains and sodium benzoate on the characteristics of corn silage in a hot-climate environment显示文摘 | Silva N C D Santos J P D Avila C L S | 2014 | Grassland Science2014，60，3： | 1 |
| 16 | Serological evidence of hepatitis E virus infection in different animal species from the Southeast of Brazil显示文摘 | Vitral C L Pinto M A Lewis-Ximenez L L Khudyakov Y E dos Santos D R Gaspar A M | 2005 | Mere Inst Oswaldo Cruz2005，100，2： | 1 |
| 17 | The positively charged surface of herpes simplex virus UIA2 mediates DNA binding显示文摘 | KOMAZIN - MEREDITH G SANTOS W L FILMAN D J | 2008 | J Biol Chem2008，283，10： | 1 |
| 18 | Finishingprocess analysis between honing and hard hobbing in pinion gears applied to a steering system显示文摘 | Santos S P D BrandaoL C GaUicchio L H | 2012 | Energy Procedia2012，14，： | 1 |
| 19 | Shape memory foamsof microbial polyestester for biomedical applications显示文摘 | Quadrini F Bellisario D Santo L | 2013 | Polymer-Plastics Technology and Engineering2013，52，6： | 1 |
| 20 | Compressed sensing MRI 显示文摘 | Lustig M Donoho D L Santos J M | 2008 | IEEE Signal Processing Magazine2008，25，2： | 1 |
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