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| 1 | Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis显示文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis. | Giliane Belarmino Maria Cristina Gonzalez Raquel S Torrinhas Priscila Sala Wellington Andraus Luiz Augusto Carneiro D'Albuquerque Rosa Maria R Pereira Valéria F Caparbo Graziela R Ravacci Lucas Damiani Steven B Heymsfield Dan L Waitzberg | 2017 | World Journal of Hepatology2017，9，7： | 11 |
| 2 | 几种转基因植物体细胞克隆变异的多样性研究显示文摘分析了杨树、水稻和甘蔗转基因植株体细胞克隆的表型变异和基因组DNA多态性。探讨了以下问题 :转基因植株体细胞克隆的 1 )表型多样性 ,2 )基因组DNA多样性 ,3)二者的相关性 ,4)表型变异和DNA变异的可遗传特性 ,5)产生的可能原因 ,以及 6)在农业生产上的应用。 | 郑易之 Sala F | 2001 | 植物研究2001，21，2： | 5 |
| 3 | Functional Heterogeneity of Cancer-Associated Fibroblasts from Human Colon Tumors Shows Specific Prognostic Gene Expression Signature显示文摘 | Mercedes Herrera Abul B.M.M.K. Islam Alberto Herrera Paloma Martín Vanesa García Javier Silva Jose M. Garcia Clara Salas Ignacio Casal Antonio García de Herreros Félix Bonilla Cristina Pe?a | 2013 | Clinical Cancer Research2013，，21： | 2 |
| 4 | An outbreak of norovirus infection in a longterm -care unit in spain显示文摘 | Navarro G Sala RM Segura F | 2005 | Infect Control Hosp Epidemiol2005，26，3： | 1 |
| 5 | Surgery for intramedullary spinal cord tumors: the role of intraoperative (neurophysiological) monitoring显示文摘 | Sala F Bricolo A Faccioli F | 2007 | Eur Spine J2007，16，： | 1 |
| 6 | The role of intraoperative neurophysiology in the pro- tection ordocumentation of surgically induced injury to the spinal cord 显示文摘 | Deletis V Sala F | 2001 | Ann N Y Acad Sci2001，939，： | 1 |
| 7 | Vitamin K antagonists or low-rnolecular- weight heparin for the long term treatment of symptomatic venous thromboembo- lism 显示文摘 | Andras A Sala Tenna A Crawford F | 2012 | Cochrane Database Syst Rev2012，10，19： | 1 |
| 8 | Secondary forest age and tropical forest biomass estimation using thematic mapper imagery显示文摘 | NELSON R F KIMES D S SALAS W A | 2000 | Bioscience2000，50，5： | 1 |
| 9 | Back to square one: Identification issues in DSGE models显示文摘 | Canova F Sala L | 2009 | Journal of Monetary Economics2009，56，4： | 1 |
| 10 | Mycobacterium tuberculosis FurA autoregulates its own expression 显示文摘 | Sala C Forti F Di Florio E | 2003 | J Bacteriol2003，185，18： | 1 |
| 11 | Vaccine antigen production in transgenic plants: strategies, gene constructs and perspectives显示文摘 | Sala F Rigano MM Barbante A | 2003 | Vaccine2003，21，78： | 1 |
| 12 | Intraoperative neurophysiologiegl monitoring of the spinal cord during spinal cord and spine surgery:a review focus on the cortieospinal tracts显示文摘 | Deletis V Sala F | 2008 | Clin Neurophysiol2008，119，： | 1 |
| 13 | HMG-CoA reductase inhibitor simvastatin inhibits cell cycle progression at the GI/S checkpoint in immortalized lymphocytes from Alzhei- mer's disease patients independently of cholesterol- lowering effects显示文摘 | Sala S G Muloz U Bartolom6 F | 2008 | J Pharmacol Exp Ther2008，324，1： | 1 |
| 14 | An assessement of global energy resource economic potentials 显示文摘 | Mercure J F Salas P | 2012 | Energy2012，46，1： | 1 |
| 15 | Transcriptional regulation of furA and katG upon oxidative stress in Mycobacterium smegmatis 显示文摘 | Milano A Forti F Sala C | 2001 | J Bacteriol2001，183，23： | 1 |
| 16 | Reliability of neurophysiological monitoring of the lumbosacral nervous system during tethered cord release显示文摘 | Chang D Krzan M | 2000 | Childs Nerv Syst2000，16，： | 1 |
| 17 | Intraoperative neurophysiological monitoring of the spi-nal cord during spinal cord and spine surgery:a review focus on the corti-cospinal tracts显示文摘 | Deletis V Sala F | 2008 | Clin Neurophysiol2008，119，： | 1 |
| 18 | Resveratrol structure and ceramide-associated growth inhibition in prostate cancer cells显示文摘 | Sala G Minutolo F Macchia M | 2003 | Drugs Exp Clin Res2003，29，56： | 1 |
| 19 | Chronic intestinal pseudo - ob- struction in patients with systemic lupus erythematosus: report of four cases显示文摘 | Ceccato F Salas A G6ngora V | 2008 | Clin Rheumatol2008，27，3： | 1 |
| 20 | Protein microarrays on midtrimester amniotic fluids: a novel approach for the diagnosis of early intrauterine inflammation related to preterm delivery显示文摘 | La Sala GB Ardizzoni A Capodanno F | 2012 | Int J Immunopathol Pharmacol2012，25，4： | 1 |
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