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| 1 | Autologous CD34^+ and CD133^+ stem cells transplantation in patients with end stage liver disease显示文摘AIM:To assess the utility of an autologous CD34 + and CD133 + stem cells infusion as a possible therapeutic modality in patients with end-stage liver diseases.METHODS:One hundred and forty patients with endstage liver diseases were randomized into two groups.Group 1,comprising 90 patients,received granulocyte colony stimulating factor for five days followed by autologous CD34 + and CD133 + stem cell infusion in the portal vein.Group 2,comprising 50 patients,received regular liver treatment only and served as a control group.RESULTS:Near normalization of liver enzymes and improvement in synthetic function were observed in 54.5% of the group 1 patients;13.6% of the patients showed stable states in the infused group.None of the patients in the control group showed improvement.No adverse effects were noted.CONCLUSION:Our data showed that a CD34 + and CD133 + stem cells infusion can be used as supportive treatment for end-stage liver disease with satisfactory tolerability. | Hosny Salama Abdel-Rahman N Zekri Abeer A Bahnassy Eman Medhat Hanan A Halim Ola S Ahmed Ghada Mohamed Sheren A Al Alim Ghada M Sherif | 2010 | World Journal of Gastroenterology2010，16，42： | 16 |
| 2 | Development of an Arabic version of the National Eye Institute Visual Function Questionnaire as a tool to study eye diseases patients in Egypt显示文摘AIM:To develop and test an Arabic version of the National Eye Institute Visual Function Questionnaire-25(NEI-VFQ-25).METHODS:NEI-VFQ-25 was translated into Arabic according to WHO translation guidelines. We enrolled adult consenting patients with bilateral chronic eye diseases who presented to 14 hospitals across Egypt from October to December 2012, and documented their clinical findings. Psychometric properties were then tested using STATA.RESULTS:We recruited 379 patients, whose mean age was(54.5±15)y. Of 46.2% were males, 227 had cataract,31 had glaucoma, 23 had retinal detachment, 37 had diabetic retinopathy, and 61 had miscellaneous visual defects. Non-response rate and the floor and ceiling numbers of the Arabic version(ARB-VFQ-25) were calculated. Internal consistency was high in all subscales(except general health), with Cronbach-α ranging from0.702-0.911. Test-retest reliability was high(intraclass correlation coefficient 0.79).CONCLUSION:RB-VFQ-25 isareliableandvalidtool for assessing visual functions of Arabic speaking patients. However, some questions had high non-response rates and should be substituted by available alternatives. Our results support the importance of including self-reported visual functions as part of routine ophthalmologic examination. | Nizar Saleh Abdelfattah Mohamed Amgad Ahmed A Salama Marina E Israel Ghada A Elhawary Ahmed E Radwan Mohamed M Elgayar Tamer M EL Nakhal Islam T Elkhateb Heba A Hashem Doha K Embaby Amira A Elabd Reem K Elwy Magdi S Yacoub Hamdy Salem Mohamed Abdel-Baqy Ahmad Kassem | 2014 | International Journal of Ophthalmology(English edition)2014，7，5： | 8 |
| 3 | Role of relevant immune-modulators and cytokines in hepatocellular carcinoma and premalignant hepatic lesions显示文摘AIM To assess the levels of different immune modulators in patients with hepatocellular carcinoma(HCC),in relation to other hepatic diseases.METHODS Eighty-eight patients were included in the current study and represented patients with HCC(20),liver cirrhosis(28) and chronic hepatitis(CH;25),and normal controls(NC;15).Peripheral blood was isolated for immunophenotyping of active myeloid dendritic cells(m DCs;CD1 c and CD40),mature inactive myeloid cells(CD1 c and HLA),active plasmacytoid cells(p DCs;CD303 and CD40),mature inactive p DCs(CD30 and HLA),active natural killer(NK) cells(CD56 and CD161),active NK cells(CD56 and CD314) and inactive NK cells(CD56 and CD158) was done by flow cytometry.Serum levels of interleukin(IL)-2,IL-10,IL-12,IL-1β,interferon(IFN)-α,IFN-γ and tumor necrosis factor(TNF)-αR2 were assessed by ELISA.RESULTS Active m DCs(CD1 C+/CD40+) and inactive m DCs(CD1 c+/HLA+) were significantly decreased in HCC patients in relation to NC(P < 0.001).CD40+ expression on active p DCs was decreased in HCC patients(P < 0.001),and its level was not significantly changed among other groups.Inactive p DCs(CD303+/HLA+),inactive NKs(CD56+/CD158+) and active NKs(CD56+/CD161+) were not statistically changed among the four groups studied;however,the latter was increased in CH(P < 0.05).NKG2 D was statistically decreased in HCC,CH and cirrhosis(P < 0.001),and it was not expressed in 63%(12/20) of HCC patients.There was significant decrease of IL-2,IFN-α and IFN-γ(P < 0.001),and a significant increase in IL-10,IL-1β,and TNF-αR2(P <0.01,P < 0.001 and P < 0.001;respectively) in HCC patients.There was inverted correlation between IL-12 and IL-1β in HCC(r =-0.565,P < 0.01),with a strong correlation between p DCs(CD303+/CD40+) and NKs(CD56+/CD161+;r = 0.512,P < 0.05) as well as inactive m DCs(CD1 c+/HLA+) and inactive NK cells(CD56+/CD158+;r = 0.945,P < 0.001).CONCLUSION NKG2 D,CD40,IL-2 and IL-10 are important modulators in the development and progression of HCC. | Abdel-Rahman N Zekri Somaya El Deeb Abeer A Bahnassy Abeer M Badr Mona S Abdellateif Gamal Esmat Hosny Salama Marwa Mohanad Ahmed Esam El-dien Shimaa Rabah Assmaa Abd Elkader | 2018 | World Journal of Gastroenterology2018，24，11： | 6 |
| 4 | A SiC14-ZnC12 induced general, mild and efficient one-pot, three- component synthesis of fl-amido ketone libraries 显示文摘 | Tarek A Salama Saad S Elmorsy Abdel-Galel M Khalil | 2007 | Tetrahedmn Letters2007，48，： | 1 |
| 5 | Reliability of automated volumetric measurement of multiple growing follicles in controlled ovarian hyperstimulation显示文摘 | Lamazou F Arbo E Salama S | | 0，，06： | 1 |
| 6 | Mechanisms of Gastro- protective Effects of Ethanolic Leaf Extract of Jasminumsambac a- gainst HC1/Ethanol-lnduced Gastric Mucosal Injury in Rats 显示文摘 | Alrashdi A S Salama S M Alkiyumi S S | 2012 | Evi- dence-based complementary and alternative medicine: eCAM2012，2012，78： | 1 |
| 7 | Comparision of three instruments in predicting accidental falls in selected inpatients in a general teaching hospital 显示文摘 | Eagle D J Salama S Whitman D | 1999 | J Gerontol Nurs1999，25，7： | 1 |
| 8 | Oppo- sition-Based differential evolution显示文摘 | Rahnamayan S Tizhoosh H R Salama M M A | 2008 | IEEE Transac- tions on Evolutionary Computation2008，12，1： | 1 |
| 9 | Capacitor placement in distribution systems using heuristic search'strategies 显示文摘 | M Chis M M A Salama S Jayaram | 1997 | IEE Proceed- ings - Generation Transmission and Distribution1997，144，3： | 1 |
| 10 | Opposition based differemial evolution显示文摘 | RAHNAMAYAN S TIZHOOSH H R SALAMA M M A | 2008 | IEEE Trans on Evolutionary Computation2008，12，1： | 1 |
| 11 | Upper lobe fibrocavitary disease in a patient with back pain and stiffness显示文摘 | Thai D Ratani RS Salama S | 2000 | Chest2000，118，： | 1 |
| 12 | Opposition versus randomness in soft computing techniques 显示文摘 | Rahnamayan S Tizhoosh H R Salama M | 2008 | Applied Soft Computing2008，8，2： | 1 |
| 13 | Preparation and characterization of controlled release co-spray dried drug-polymer microparticles for inhalation 1 :intluence of polymer concentration on physical and in vitro characteristics 显示文摘 | Salama R Hoe S Chan H | 2005 | Eur J Pharm Biophann2005，69，2： | 1 |
| 14 | Opposition versus randomness in soft computing techniques显示文摘 | RAHNAMAYAN S TIZItOOSH H R SALAMA M M A | 2008 | Applied Soft Computing2008，8，2： | 1 |
| 15 | Evaluation of multicast routing algorithms for real-time communication on high speed networks显示文摘 | H F Salama D S Reeves | 1997 | IEEE Journal on selected areas in communication1997，15，3： | 1 |
| 16 | Evaluation of Multicast Routing Algorithms for Real-time Communication on High-speed Networks显示文摘 | Salama H F Reeves D S Viniotis Y | 1997 | IEEE Journal on Select Areas in Communications1997，15，3： | 1 |
| 17 | Renal and ocular targets for therapy in Wegener' s granulomatosis显示文摘 | Joshi L Hamour S Salama AD | 2009 | Inflamm Allergy Drug Targets2009，8，： | 1 |
| 18 | Sinus bone grafting procedures using ultrasonic bone surgery:5-year experience显示文摘 | Blus C Szmukler-Moncler S Salama M | 2008 | Int J Periodontics Restorative Dent2008，28，3： | 1 |
| 19 | Needle aspiration cylol ogy of sebaceous carcinoma显示文摘 | Hood I C Qizilbash A H Salama S S | 1984 | Acta Cytol1984，28，： | 1 |
| 20 | Two-stage versus one-stage-is there really a controversy 显示文摘 | GARBER D A SALAMA H S ALAMA M A | 2001 | J Periodentol2001，72，3： | 1 |
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