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| 1 | 高效液相色谱-紫外检测法同时测定药物制剂及人体血清中的奥美沙坦酯和厄贝沙坦及氢氯噻嗪(英文)显示文摘A simple,selective,sensitive,precise,simultaneous high performance liquid chromatographic analysis of serum samples and commercial tablet formulation containing hydrochlorothiazide,olmesartan medoxomil and irbesartan are reported.Good chromatographic separation was achieved using a μ-Bondapak,C18 column(15 cm×4.6 mm,5 μm),and a mobile phase consisting of acetonitrile-0.2% acetic acid aqueous solution(50∶50,v/v)at a flow rate of 1.0 mL/min.The ultraviolet detector was set at a wavelength of 260 nm.Hydrochlorothiazide,olmesartan medoxomil,and irbesartan were eluted at 1.2,3.8,and 4.4 min,respectively.No extraneous materials were found to interfere.The method uses protein precipitation with acetonitrile for the preparation of serum sample.The linear ranges for hydrochlorothiazide,olmesartan medoxomil,and irbesartan were 6.25-18.75,20-60,and 75-225 ng/mL,respectively.The recoveries of hydrochlorothiazide,olmesartan medoxomil,and irbesartan in spiked samples were all greater than 98%,and their relative standard deviations were less than 2.0%.The limits of detection were 1,2,and 2 ng/mL for hydrochlorothiazide,olmesartan medoxomil,and irbesartan,respectively,and the limits of quantification were 3 ng/mL,which allow their determination at the expected serum concentration levels. | SULTANA Najma ARAYNE M Saeed ALI S Shahid SAJID Shahnawaz | 2008 | 色谱2008，26，5： | 6 |
| 2 | Drainage vs. non-drainage after cholecystectomy for acute cholecystitis:a retrospective study显示文摘Many surgeons practice prophylactic drainage after cholecystectomy without reliable evidence,this study was conducted to answer the question whether to drain or not to drain after cholecystectomy for acute calculous cholecystitis.A retrospective review of all patients who had cholecystectomy for acute cholecystitis in Aseer Central Hospital,Abha,Saudi Arabia,was conducted from April 2010 to April 2012.Data were extracted from hospital case files.Preoperative data included clinical presentation,routine investigations and liver function tests.Operative data included excessive adhesions,bleeding,bile leak,and drain insertion.Complicated cases such as pericholecystic collections,mucocele and empyema were also reported.Patients who needed therapeutic drainage were excluded.Postoperative data included hospital stay,volume of drained fluid,time of drain removal,and drain site problems.The study included 103 patients allocated into two groups;group A(n = 38) for patients with operative drain insertion and group B(n = 65) for patients without drain insertion.The number of patients with preoperative diagnosis of acute non-complicated cholecystitis was significantly greater in group B(80%) than group A(36.8%)(P < 0.001).Operative time was significantly longer in group A.All patients who were converted from laparoscopic to open cholecystectomy were in group A.Multivariate analysis revealed that hospital stay was significantly(P < 0.001) longer in patients with preoperative complications.There was no added benefit for prophylactic drain insertion after cholecystectomy for acute calculous cholecystitis in non-complicated or in complicated cases. | Mohammed A Bawahab Walid M Abd El Maksoud Saeed A Alsareii Fahad S Al Amri Hala F Ali Abdul Rahman Nimeri Abdul Rahman M Al Amri Adel A Assiri Mohammed I Abdul Aziz | 2014 | The Journal of Biomedical Research2014，28，3： | 3 |
| 3 | Candida esophagitis:Risk factors in non-HIV population in Pakistan显示文摘AIM:Candida esophagitis is a frequent infection in immunocompromised patients. This study was designed to determine its characteristics in non- human immune deficiency virus (HIV) infected patients attending a teaching hospital.METHODS: Clinical records of all patients coded by international classification of diseases 9th revision with clinical modifications'(ICD-9-CM), with candida esophagitis diagnosed by esophagogastroduodenoscopy (EGD) and histopathology over a period of 5 years were studied.RESULTS: Fifty-one patients (27 males, 24 females, range 21-77 years old and mean age 52.9 years) fulfilled the criteria (0.34% of the EGD). The common predisposing factors were carcinoma (OR 3.87, CI 1.00-14.99) and diabetes mellitus (OR 4.39, CI 1.34-14.42). The frequent clinical symptoms were retrosternal discomfort, dysphagia and epigastric abdominal pain with endoscopic appearance of scattered mucosal plaques. Another endoscopic lesion was associated with candida esophagitis in 15% patients.CONCLUSION: Carcinomas, diabetes mellitus, corticosteroid and antibiotic therapy are major risk factors for candida esophagitis in Pakistan. It is an easily managed complication that responds to treatment with nystatin. | Javed Yakoob Wasim Jafri Shahab Abid Nadeem Jafri Muhammad Islam Saeed Hamid Hasnain A Shah Akbar S Hussainy | 2003 | World Journal of Gastroenterology2003，9，10： | 2 |
| 4 | Short and long-term outcomes of angle supported phakic intraocular lens implantation in high myopic eyes显示文摘This cohort study included 36 eyes of 21 patients with high myopia treated with angle supported phakic intraocular lens(p IOL).Endothelial cell density(ECD) at baseline,6 mo and 3 y were 3017±296,2775±265 and 2558±299 cells/mm^2 respectively.ECD loss at 6 mo was 7.2% and annual ECD loss was 3% over 36 mo.Corrected distance visual acuity at 36 mo was 0.4 log MAR or better in 32(88.9%) eyes.Intraocular pressure did not change(P=0.9).No eyes developed cataract,retinal detachment or pupillary distortion.Angle supported p IOL gives good visual outcome.Endothelial cell loss should be monitored. | Saeed Al-Qahtani Khalid Al-Afraj Mohanna Al-Jindan Ali S Al-Beshri Rajiv KhANDekar | 2018 | International Journal of Ophthalmology(English edition)2018，11，5： | 2 |
| 5 | Interinstitutional and intrainstitutional transmission of a strain of Acineto- bacter baumanniidetected by molecular analysis: compari- son of pulsed-field gel electrophoresis and repetitive se- quence-based polymerase chain reaction 显示文摘 | Saeed S Fakih M G Riederer K | 2006 | Infect Con- trol Hosp Epidemiol2006，27，9： | 1 |
| 6 | Energy efficiency in heterogeneous wireless access networks显示文摘 | NAVARATNARAJAH S SAEED A DIANATI M | 2013 | IEEE Wireless Communications2013，20，5： | 1 |
| 7 | A study on chemical properties of groundwater and soil in ophiolitic rocks in Firuzard,east of Shahrood,Iran:With emphasis to heavy metal contamination显示文摘 | Hajizardeh N Ghol H K Saeed S | 2011 | Environmental Monitoring and Assessment2011，174，14： | 1 |
| 8 | Interinstitutional and intrain- stitutional transmission of a strain of Acinetobacter baumannii detected by molecular analysis: comparison of pulsed -field gel electrophoresis and repetitive sequence - based polymerase chain reaction 显示文摘 | Saeed S Fakih MG Riederer K | 2006 | Infect Control Hosp Epidemiol2006，27，9： | 1 |
| 9 | A Simple and Selective Flow-Injection Potentiometric Method for Determination of Iodide Based on a Coated Glassy Carbon Electrode Sensor显示文摘 | Saeed S B Mohammad K A | 2007 | Int J Electrochem Sci2007，，2： | 1 |
| 10 | Complications following adult cochlear implantation: experience in Manchester显示文摘 | GREEN K M BHATT Y M SAEED S R | 2004 | J Laryngol Otol2004，118，： | 1 |
| 11 | Association of the angiotensin-converting enzyme (ACE) gene G2350A dimorphism with essential hypertension 显示文摘 | Saeed Mahmood M Saboohi K Osman Ali S | 2003 | J Hum Hypertens2003，17，： | 1 |
| 12 | Association of angiotensin converting enzyme gene polymorphisms with left ventricular hypertrophy显示文摘 | Saeed M Saleheen D Siddiqui S | 2005 | Hypertens Res2005，28，： | 1 |
| 13 | Association of Gprotein beta-3 subunit gene ( GNB3 ) T825 allele with Type Ⅱ diabetes显示文摘 | KIANI J G SAEED M PARVEZ S H | 2005 | Neuro Endocrinol Lett2005，26，2： | 1 |
| 14 | Nitrogen response of barley plants to nitrogen and zinc fertilization in calcareous soils显示文摘 | Abdul M Saeed A S | 1979 | Agri culture Chemistry1979，23，34： | 1 |
| 15 | Preparationof amidoxime-modified polyacrylonitrile ( PAN-oxime )nanofibers and their applications to metal ions adsorp-tion 显示文摘 | SAEED K HAIDER S PARK S Y | 2008 | Journal of Membrane Science2008，，322： | 1 |
| 16 | Swelling and elec- troresponsive characteristics of gelatin immobilized onto multi walled carbon nanotubes 显示文摘 | Haider S Park S Y Saeed K | 2007 | Sensor Actuator B2007，124，2： | 1 |
| 17 | Multi-walled carbon nanotube paste electrode for selectrue whammetric detection of isoniazid 显示文摘 | Saeed S Mandana A | 2007 | Microchim Acta2007，157，： | 1 |
| 18 | Myocardial ischaemia and reperfusion injury:reactive oxygen species and the role of neutrophil 显示文摘 | Saeed S A Waqar M A Zubairi A J | 2005 | J Coil Physicians Surg Pak2005，15，8： | 1 |
| 19 | Eugenol:a dual inhibitor of platelet-activating factor and arachidonic acid metabolism显示文摘 | Saeed S A Simjee R U Shamim G | 1995 | Phytomedicine1995，2，1： | 1 |
| 20 | Activation of apoptosis signal regulating kinase 1 ( ASK1 ) and transloeation of death-associated protein, Daxx, in substantia nigra pars compaeta in a mouse model of Parkinson's disease : protection by alpha-lipoie acid 显示文摘 | Karunakaran S Diwakar L Saeed' U | 2007 | FASEB J2007，21，9： | 1 |
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