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| 1 | Pre-and postoperative systemic hemodynamic evaluation in patients subjected to esophagogastric devascularization plus splenectomy and distal splenorenal shunt:A comparative study in schistomomal portal hypertension显示文摘AIM: To investigate the systemic hemodynamic effects of two surgical procedures largely employed for treatment of schistosomal portal hypertension. METHODS: Thirty-six patients undergoing elective surgical treatment of portal hypertension due to hepatosplenic mansonic schistosomiasis were prospectively evaluated. All patients were subjected to preoperative pulmonary artery catheterization; 17 were submitted to esophagogastric devascularization and splenectomy (EGDS) and 19 to distal splenorenal shunt (DSRS). The systemic hemodynamic assessment was repeated 4 d after the surgical procedure. RESULTS: Preoperative evaluation revealed (mean ± SD) an increased cardiac index (4.78 ± 1.13 L/min per m2),associated with a reduction in systemic vascular resistance index (1457 ± 380.7 dynes.s/cm5.m2). The mean pulmonary artery pressure (18 ± 5.1 mmHg) as well as the right atrial pressure (7.9 ± 2.5 mmHg) were increased,while the pulmonary vascular resistance index (133 ± 62 dynes.s/cm5.m2) was decreased. Four days after EGDS,a significant reduction in cardiac index (3.80 ± 0.4 L/min per m2,P < 0.001) and increase in systemic vascular resistance index (1901.4 ± 330.2 dynes.s/cm5. m2,P < 0.001) toward normal levels were observed. There was also a significant reduction in pulmonary artery pressure (12.65 ± 4.7 mmHg,P < 0.001) and no significant changes in the pulmonary vascular resistance index (141.6 ± 102.9 dynes.s/cm5.m2). Four days after DSRS,a non-significant increase in cardiac index (5.2 ± 0.76 L/min per m2) and systemic vascular resistance index (1389 ± 311 dynes.s/cm5.m2) was observed. There was also a non-significant increase in pulmonary artery pressure (19.84 ± 5.2 mmHg),right cardiac work index (1.38 ± 0.4 kg.m/m2) and right ventricular systolic work index (16.3 ± 6.3 g.m/m2),without significant changes in the pulmonary vascular resistance index (139.7 ± 67.8 dynes.s/cm5.m2). CONCLUSION: The hyperdynamic circulatory state observed in mansonic schistosomiasis was corrected by EGDS,but was maintained in patients who underwent DSRS. Similarly,the elevated mean pulmonary artery pressure was corrected after EGDS and maintained after DSRS. EGDS seems to be the most physiologic surgery for patients with schistosomal portal hypertension. | Roberto de Cleva Paulo Herman Luis Augusto Carneiro D’albuquerque Vincenzo Pugliese Orlando Luis Santarem William Abro Saad | 2007 | World Journal of Gastroenterology2007，13，41： | 9 |
| 2 | A closed-form approximation for ground return impedance of underground cables显示文摘 | Saad O Gaba G Giroux M | 1996 | IEEE Trans on PWRD1996，11，3： | 2 |
| 3 | A binaphthol-substituted tetrathiafulvalene with axial ehirality and its enantiopure TCNQF4 charge-transfer salts显示文摘 | Saad A Jeannin O Fourmigue M | 2011 | New J Chem2011，35，： | 1 |
| 4 | Expression of alpha-hemoglobin stabilizing protein gene during human erythropoiesis显示文摘 | DOS SANTOS C O DUARTE A S SAAD S T | 2004 | Exp Hematol2004，32，2： | 1 |
| 5 | Depression during pregnancy: Causes, risk factors and treatment显示文摘 | Khan M O Saad S M A | 2010 | J Pak Med Assoc2010，60，1： | 1 |
| 6 | Interleukin 1 beta and tumor necrosis factor levels in stored platelet concentrates and the association with gene polymorphisms 显示文摘 | Addas-Carvalh O M Origa A F Saad S T | 2004 | Transfusion2004，44，7： | 1 |
| 7 | A Binaphthol-substitutedtetrathiafulvalene with axial chirality and its enantiopureTCNQF4 charge-transfer salts 显示文摘 | Saad A Jeannin O Fourmigue M | 2011 | New J Chem2011，35，： | 1 |
| 8 | A close-form approximation for ground return impedance of underground cables显示文摘 | Saad O Gaba G Giroux M | 1996 | IEEE Transactions on Power Delivery1996，11，3： | 1 |
| 9 | Response of broad bean (Vicia faba ) to method of phosphorus application and foliar application of micronutrients 显示文摘 | Thalooth A T Yakout G M Saad A O M | 2001 | Plant Nutrition2001，92，1： | 1 |
| 10 | Neural-estimator- based Kalman filter structure 显示文摘 | Nneme L N Saad M O'Shea J | 2000 | J Elect & Comp Eng2000，25，2： | 1 |
| 11 | Possible role of low level laser therapy on bone turnover in ovariectomized rats显示文摘 | Saad A Yamany ME Abbas O | 2010 | Endocr Regul2010，44，： | 1 |
| 12 | Occurrence and distribution of chemical pollutants in lake Mariut, Egypt 显示文摘 | Saad M A H Ezzat A A E1 Rayis O A | 1981 | Heavy Metals Water Air and Soil Pollution1981，16，4： | 1 |
| 13 | The structure and stability of sulfated alumina and titania 显示文摘 | Saur O Bensitel M Mohammed Saad A B | 1986 | J Catal1986，99，1： | 1 |
| 14 | Exposure of infants to aflatoxin M1 from mothers' breast milk in Abu Dhabi, UAE 显示文摘 | SAAD A M ABDELGADIR A M MOSS M O | 1995 | FoodAddit Contain1995，12，2： | 1 |
| 15 | Determination of aminoglutethimide enantiomers in pharmaceutical formulations by capillary electrophoresis using methylated -β- cyclodextrin as a chiral selector and computational calculation for their respective inclusion complexes 显示文摘 | Abdalla A Elbashir Fakhr Eldin O Suliman Bahruddin Saad Hassan Y Aboul - Enein | 2009 | Talanta2009，77，： | 1 |
| 16 | The structure and stability of sulfated alumina and titania 显示文摘 | SAUR O BENSITEL M SAAD A B M | 1986 | Catalysis today1986，99，： | 1 |
| 17 | Adaptation to temperature of nitric oxide-producing nitrate-reducing bacterial populations in soil 显示文摘 | Saad 0 A L O Conrad R | 1993 | Systematic and Applied Microbiology1993，16，1： | 1 |
| 18 | Maintaining a physiological blood glucose level with 'glucolevel',a combination of four anti-diabetes plants used in the traditional Arab herbal medicine显示文摘 | Said O Fulder S Khalil K Azaizeh H Kassis E Saad B | 2008 | Evid Based Complement Alternat Med2008，5，4： | 1 |
| 19 | Analysis and design of a circular TEol mode transducer显示文摘 | Saad S S Davies J B Davies O J | 1977 | Microwave Optics and Acoustics1977，1，2： | 1 |
| 20 | Effect of Suturing Technique and Urethral Plate Characteristics on Complica- tion Rate Following Hypospadias Repair: A Prospective Randomized Study 显示文摘 | Sarhan O Saad M Helmy T | 2009 | J Urol2009，182，2： | 1 |
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