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| 1 | Helicobacter species and common gut bacterial DNA in gallbladder with cholecystitis显示文摘AIM:To analyze the association between Helicobacter spp. and some common gut bacteria in patients with cholecystitis. METHODS:A nested-polymerase chain reaction (PCR), specif ic to 16S rRNA of Helicobacter spp. was performed on paraff in-embedded gallbladder samples of 100 cholecystitis and 102 control cases. The samples were also analyzed for some common gut bacteria by PCR. Positive samples were sequenced for species identif ication. RESULTS: Helicobacter DNA was found in seven out of 100 cases of acute and chronic cholecystitis. Sequence analysis displayed Helicobacter pullorum (H. pullorum) in six cases and Helicobacter pylori in one; H. pullorum was only found in cases with metaplasia. Control sam-ples were negative for Helicobacter spp. and some common gut bacteria. There was a signif icant difference (P=0.007) between cholecystitis and control samples for Helicobacter DNA.CONCLUSION:A possible relationship was detected between Helicobacter DNA and cholecystitis. Further serological and immunohistochemical studies are needed to support these data. | Peren H Karagin Unne Stenram Torkel Wadstrm sa Ljungh | 2010 | World Journal of Gastroenterology2010，16，38： | 3 |
| 2 | Updated worldwide survey on the methods,efficacy,and safety of catheter ablation for human atrial fibrillation显示文摘 | Cappato R Calkins H Chen SA | | Circ Arrhythm Electrophysiol0，，： | 2 |
| 3 | Global research trends in the microbiome related to irritable bowel syndrome: A bibliometric and visualized study显示文摘BACKGROUND Irritable bowel syndrome(IBS) is a common functional gastrointestinal disorder. Dysregulation of the gut–brain axis plays a central role in the pathophysiology of IBS. It is increasingly clear that the microbiome plays a key role in the development and normal functioning of the gut–brain axis.AIM To facilitate the identification of specific areas of focus that may be of relevance to future research. This study represents a bibliometric analysis of the literature pertaining to the microbiome in IBS to understand the development of this field.METHODS The data used in our bibliometric analysis were retrieved from the Scopus database. The terms related to IBS and microbiome were searched in titles or abstracts within the period of 2000–2019. VOSviewer software was used for data visualization.RESULTS A total of 13055 documents related to IBS were retrieved at the global level. There were 1872 scientific publications focused on the microbiome in IBS. There was a strong positive correlation between publication productivity related to IBS in all fields and productivity related to the microbiome in IBS(r = 0.951, P < 0.001). The United States was the most prolific country with 449(24%) publications, followed by the United Kingdom(n = 176, 9.4%), China(n = 154, 8.2%), and Italy(n = 151, 8.1%). The h-index for all retrieved publications related to the microbiome in IBS was 138. The hot topics were stratified into four clusters:(1) The gut–brain axis related to IBS;(2) Clinical trials related to IBS and the microbiome;(3) Drugmediated manipulation of the gut microbiome;and(4) The role of the altered composition of intestinal microbiota in IBS prevention.CONCLUSION This is the first study to evaluate and quantify global research productivity pertaining to the microbiome in IBS. The number of publications regarding the gut microbiota in IBS has continuously grown since 2013. This finding suggests that the future outlook for interventions targeting the gut microbiota in IBS remains promising. | Sa'ed H Zyoud Simon Smale W Stephen Waring Waleed Sweileh Samah W Al-Jabi | 2021 | World Journal of Gastroenterology2021，27，13： | 2 |
| 4 | Global research on Clostridium difficile-associated diarrhoea:A visualized study显示文摘BACKGROUND Clostridioides(Clostridium)difficile(C.difficile)is still the most common cause of healthcare-associated diarrhoea and is increasing in prevalence as a communityacquired infection.In addition,the emergence of antibiotic resistance in C.difficile can increase the likelihood of the disease developing and/or spreading.AIM To provide an up-to-date picture of the trends in publications related to C.difficile infection,together with specific insights into hot-button issues in this field.METHODS Publications on C.difficile infections in the field of microbiology between 2001 and 2020 were identified from the Scopus database and Reference Citation Analysis.Bibliometric indicators were determined,including the number and type of publications,countries,affiliations,funding agencies,journals and citation patterns.VOSviewer was used to determine research areas and hot-button issues by identifying recurring terms with a high relative occurrence in the title and abstract.RESULTS A total of 8127 documents on‘C.difficile-associated diarrhoea’published between 2001 and 2020 were retrieved from the Scopus database.In the last decade,there has been a significant almost fourfold increase in the number of published papers on this topic.The United States was among the countries(44.11%)with the most publications,and the most involved institution was the University of Leeds in the United Kingdom(2.50%).Three clusters of research were identified and included‘illness spectrum and severity,as well as the signs,symptoms and clinical pathogenesis of C.difficile’;‘laboratory diagnosis and characterization of C.difficile’and‘risk factors for C.difficile infection’.CONCLUSION This study contains the most up-to-date and comprehensive data ever compiled in this field.More international research and cross-institutional collaborations are needed to address more global C.difficile concerns and to benefit from greater sharing of expertise,which will result in higher quality or more effective studies in the future.Promising research avenues in the near future may draw the attention of relevant scientists and funding organizations and open up novel C.difficile infection–based diagnosis and treatment approaches. | Sa'ed H Zyoud | 2022 | World Journal of Gastroenterology2022，28，28： | 2 |
| 5 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 6 | 遗传性肥胖与心房颤动的关系显示文摘观察性研究已经确定了体质量指数(body mass index,BMI)与心房颤动之间的关联。然而,从观察性研究中推断因果关系会受到混杂因素、逆因果关系和偏倚的影响。该研究的主要目的是应用BMI的遗传学预测因子评估BMI与心房颤动之间的因果关系。方法:纳入1987-2002年期间在美国、冰岛和荷兰实施的7个前瞻性人群队列研究中基线无心房颤动的欧洲血统个体51 646人, | 刘莉 叶鹏 Chatterjee NA Giulianini F Geelhoed B Lunetta KL Misialek JR Niemeijer MN Rienstra M Rose LM Smith AV Arking DE Ellinor PT Heeringa J Lin H Lubitz SA Soliman EZ Verweij N Alonso A Benjamin EJ Gudnason V Stricker BH van der Harst P Chasman DI Albert CM | 2017 | 中华高血压杂志2017，25，2： | 2 |
| 7 | Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing显示文摘The impact of the microenvironment on innate lymphoid cell(ILC)-mediated immunity in humans remains largely unknown.Here we used full-length Smart-seq2 single-cell RNA-sequencing to unravel tissue-specific transcriptional profiles and heterogeneity of CD127+ILCs across four human tissues.Correlation analysis identified gene modules characterizing the migratory properties of tonsil and blood ILCs,and signatures of tissue-residency,activation and modified metabolism in colon and lung ILCs.Trajectory analysis revealed potential differentiation pathways from circulating and tissue-resident naïve ILCs to a spectrum of mature ILC subsets.In the lung we identified both CRTH2+and CRTH2−ILC2 with lung-specific signatures,which could be recapitulated by alarmin-exposure of circulating ILC2.Finally,we describe unique TCR-V(D)J-rearrangement patterns of blood ILC1-like cells,revealing a subset of potentially immature ILCs with TCR-δ rearrangement.Our study provides a useful resource for in-depth understanding of ILC-mediated immunity in humans,with implications for disease. | Luca Mazzurana Paulo Czarnewski Viktor Jonsson Leif Wigge Markus Ringnér Teresa CWilliams Avinash Ravindran Åsa KBjörklund Jesper Säfholm Gunnar Nilsson Sven-Erik Dahlén Ann-Charlotte Orre Mamdoh Al-Ameri Charlotte Höög Charlotte Hedin Sylwester Szczegielniak Sven Almer Jenny Mjösberg | 2021 | Cell Research2021，31，5： | 2 |
| 8 | 瑞典海岸带可持续发展的经济评价显示文摘瑞典海岸带是自然界提供的各种商品和服务利益冲突的场所。自由出入的条件以及许多服务的公有性质增加了解决这些冲突的难度。'可持续性'是一个模糊的但被广泛接受的、找到不同利益之间合理的折衷方案的准则。联合国关于可持续发展的观点表明,海岸带管理的目的应该是可持续的生态、经济及社会文化发展。通过进一步分析经济可持续性,人们认为,关于社会变化是否意味着益或损的经济分析应该考虑环境的经济价值。本文简要地评述了在瑞典海岸带背景下开展这种经济评价所采用的方法。值得注意是,财产权的情况对于评价研究的结果很重要。本文介绍了这一总的背景之后对瑞典海岸带问题的四项研究的设计和结果进行了扼要的陈述。其中一项研究是关于改善斯德哥尔摩群岛一个海水浴场水质的经济价值。其他三项研究分别是关于改善斯德哥尔摩群岛游钓渔业的经济价值的旅行成本研究,关于恢复鳟生境的价值的更新成本研究,以及关于改善瑞典西海岸沿岸水质的经济价值的选择试验研究。 | ToreSderqvist Hkan Eggert Bjrn Olsson sa Soutukorva 林宝法 | 2005 | AMBIO-人类环境杂志2005，34，2： | 2 |
| 9 | Influence of lamination on the flexural strength of a dental castable glass ceramic 显示文摘 | al-Shehri SA Mohammed H Wilson CA | 1996 | J Prosthet Dent1996，76，1： | 1 |
| 10 | Approximate solutions for Forchheimer flow to a well 显示文摘 | Mathias SA Butler AP Zhan H | 2008 | ASCE J Hydraul Eng-ASCE2008，134，： | 1 |
| 11 | Wnt signalling regulates adult hippo - campal neurogenesis显示文摘 | Lie DC Colamarino SA Song H J | 2005 | Nature2005，437，7063： | 1 |
| 12 | Localization of gelatinase-A and gelatinase-B mRNA and protein in human gliomas显示文摘 | Muzik H Muik H | 2000 | Neuro-oncol2000，2，： | 1 |
| 13 | Serological survey of giant pandas(Ailuropoda melanoleuca),and domestic dogs and cats in Wolong Reserve,China显示文摘 | Q Xianmeng H Tingmei and MJ Appel | 1994 | J Wildl Dis1994，30，： | 1 |
| 14 | Coxsackievirus B3 induces T regulatory cells, which inhibit cardiomyopathy in tumor necrosis factor-α transgenic mice显示文摘 | H uber SA Feldman AM Sartini D | 2006 | Circ Res2006，99，10： | 1 |
| 15 | A clinical dilemma:cardiac and pericardiac echinococcosis显示文摘 | Birincioglu CL Bardakci H Kucuker SA | 1999 | Ann Thorac Surg1999，68，： | 1 |
| 16 | Influence of Lamination on Flexural strength of a dental castable glass ceramic显示文摘 | Al-Shehri SA Mohammed H Wilson CA | 1996 | Int J Prosth1996，76，： | 1 |
| 17 | A simple method for the uniform production of gastric ulceration in the rat显示文摘 | hay H Komarow SA Fels SS | 1945 | Gastroenterol1945，5，1： | 1 |
| 18 | Assessment of cerebral circulation in normal fetuses by three-dimensional power Doppler ultrasonography显示文摘 | Milani H] de Sa Barreto EQ AraujoJunior Ev | 2012 | Eur J Radiol2012，81，3： | 1 |
| 19 | Technical challenges of coronary CT angiography: today and tomorrow显示文摘 | Hassan A Nazir SA Alkadhi H | 2011 | Eur J Radiol2011，79，2： | 1 |
| 20 | Host genome polymorphisms and tuberculosis infection : What we have to say? 显示文摘 | Khalilullah SA Harapan H Hasan NA | 2013 | Egyp- tian Journal of Chest Diseases and Tuberculo- sis2013，17，1： | 1 |
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