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| 1 | Arabidopsis Squalene Epoxidase 3 (SQE3) Complements SQE1 and Is Important for Embryo Development and Bulk Squalene Epoxidase Activity显示文摘在 mevalonate 小径的 multigenic 家庭的存在为涉及植物甾醇的生合成的小径部件建议分叉的功能的角色。Squalene epoxidases (SQE ) 是这条小径的关键部件,并且 Squalene Epoxidase 1 (SQE1 ) 在这 biosynthetic 步作为基本的酶被识别了。在现在的工作,我们扩大了留下的 SQE 家庭成员的描述,种系发生地在真 SQE 和对 Brassicaceae 独占的象 SQE 一样蛋白质的一个亚科之间解决。真 SQE 家庭成员, Squalene Epoxidase 2 (SQE2 ) 和 Squalene Epoxidase 3 (SQE3 ) 的功能的描述,显示那 SQE3,然而并非 SQE2,在 Arabidopsis 贡献体积 SQE 活动,与积累 squalene 并且显示敏感到 terbinafine 的 sqe3-1 异种。我们遗传上证明 SQE3 似乎在胚胎开发起一个特别地重要的作用。另外, SQE1 和 SQE3 两个都在 endoplasmic 蜂窝胃本地化,并且 SQE3 能机能上地补充 SQE1。因此, SQE1 和 SQE3 似乎是在在 Arabidopsis 的工厂 SQE 活动的提升的二机能上地不相等的冗余的基因。 | Sara Laranjeira Vitor Amorim-Silva Alicia Esteban Monserrat Arro Albert Ferrer Rui Manuel Tavares Miguel Angel Botella Abel Rosado Herlander Azevedo | 2015 | Molecular Plant2015,8,7: | 12 |
| 2 | 高强度管线钢力学性能和冶金特性的最新进展显示文摘为了提高油气管道的输送效率,降低管道建设成本,并满足复杂环境下油气管道能稳定服役的要求,钢管行业开展了大量的工作来研发冶金和力学性能(强度、韧性及延性)优异的管线钢。介绍了高强度管线钢的最新研究进展以及基于应变设计的管线钢的力学性能。分析了化学成分、显微组织、TMCP工艺和ACC工艺等对管线钢强度、韧性和延性的影响。分析结果表明,新开发的非传统TMCP工艺有助于改善管线钢的力学性能,管线钢的强度、韧性和延性与合金元素的含量相关,最佳显微组织的开发提供了高应变能力应用所需的力学性能。分析结果还表明,对于生产低屈强比、高延伸率和足够韧性的管线钢,传统TMCP和非传统TMCP工艺均是有效的工艺路线。 | 孙宏 D BELATO ROSADO W DE WAELE D VANDER-SCHUEREN | 2017 | 焊管2017,40,9: | 6 |
| 3 | Extration of ribosomal RNA and genomic DNA from soil for studying the diversity of the indigenous bacterial community 显示文摘 | Duarte G F Rosado A S Seldin L | 1998 | Journal of Microbiological Methods1998,32,: | 2 |
| 4 | Biomarkers of hypoxic-ischemic encephalopathy:a systematic review显示文摘Background Current diagnostic criteria for hypoxic–ischemic encephalopathy in the early hours lack objective measurement tools.Therefore,this systematic review aims to identify putative molecules that can be used in diagnosis in daily clinical practice(PROSPERO ID:CRD42021272610).Data sources Searches were performed in PubMed,Web of Science,and Science Direct databases until November 2020.English original papers analyzing samples from newborns>36 weeks that met at least two American College of Obstetricians and Gynecologists diagnostic criteria and/or imaging evidence of cerebral damage were included.Bias was assessed by the Newcastle–Ottawa Scale.The search and data extraction were verified by two authors separately.Results From 373 papers,30 met the inclusion criteria.Data from samples collected in the first 72 hours were extracted,and increased serum levels of neuron-specific enolase and S100-calcium-binding protein-B were associated with a worse prognosis in newborns that suffered an episode of perinatal asphyxia.In addition,the levels of glial fibrillary acidic protein,ubiquitin carboxyl terminal hydrolase isozyme-L1,glutamic pyruvic transaminase-2,lactate,and glucose were elevated in newborns diagnosed with hypoxic–ischemic encephalopathy.Moreover,pathway analysis revealed insulin-like growth factor signaling and alanine,aspartate and glutamate metabolism to be involved in the early molecular response to insult.Conclusions Neuron-specific enolase and S100-calcium-binding protein-B are potential biomarkers,since they are correlated with an unfavorable outcome of hypoxic-ischemic encephalopathy newborns.However,more studies are required to determine the sensitivity and specificity of this approach to be validated for clinical practice. | Ines Caramelo Margarida Coelho Miguel Rosado Carla M.P.Cardoso Alexandra Dinis Carlos B.Duarte Mario Graos Bruno Manadas | 2023 | World Journal of Pediatrics2023,19,6: | 2 |
| 5 | The practical application of a process for eliciting and designing security in web service systems 显示文摘 | Carlos Gutierrez David G Rosado Eduardo Fernandez -Medina | 2009 | Information and Software Technology2009,51,12: | 1 |
| 6 | Addition of vitamins and minerals to corn and wheat flour in Mexico显示文摘 | Rosado J Camacho-Solis R Bourges H | 1999 | Salud Public Mex1999,41,: | 1 |
| 7 | Platelet signalling abnormalities in pa- tients with type 2 diabetes mellitus: A review显示文摘 | E1 Haouari M Rosado JA | 2008 | Blood Ceils Mol Dis2008,41,1: | 1 |
| 8 | Retrospective analysis of 314 or- bital fractures显示文摘 | Rosado P deViente JC | 2012 | Oral Surg Oral Med Oral Pathol Oral Radiol2012,113,: | 1 |
| 9 | Blockade of ractactivity induces Gl cell cycle arrest or apoptosis in breast cancer cells through downregulation of cyclin D1, survivin, and X -linked inhibitor of apoptosis protein 显示文摘 | Yoshida T Zhang Y Rivera Rosado LA | 2010 | Mol Cancer Ther2010,9,: | 1 |
| 10 | Effect of controlled volumetric tissue heating with radioffequency on cellulite and subcutaneous tissues of the buttocks and thighs 显示文摘 | Pino ME Rosado RH Azuela A | 2006 | Drugs Dermatol2006,5,8: | 1 |
| 11 | Analysis of the dynamics of bacterial communities in the rhizophere of the chrysanthemum via denaturing gradient gel electrophoresis and substrate utilization 显示文摘 | Duineveld B M Rosado A Elsas J D | 1998 | Appl Environ Microbiol1998,64,12: | 1 |
| 12 | Pulmonary mucorrnycosis:radiologic findings in 32 cases显示文摘 | McAdams HP Rosado de Christenson M Strollo DC | 1997 | AJR Am J Roentgenol1997,168,: | 1 |
| 13 | Study of the true clinical progression of autosomal dominant Alport syndrome in a European population 显示文摘 | Rosado C Bueno E Felipe C | 2015 | Kidney Blood Press Res2015,40,4: | 1 |
| 14 | Blockade of Racl activity induces G1 cell cycle arrest or apnptosis in breast cancer cells through downregulation of cyclin D1, survivin, and X-linked inhibitor of apoptosis protein 显示文摘 | Yoshida T Zhang Y Rivera Rosado LA | 2010 | Mol Cancer Ther2010,9,6: | 1 |
| 15 | A PCR-restriction enzyme technique for determining dengue virus subgroups within sero- types显示文摘 | Vorndam V Kuno G Rosado N | 1994 | J Virol Methods1994,48,23: | 1 |
| 16 | New Techniques to Control Dalinity-Wastewater Reuse Interactions in Golf Courses of the Mediterranean Regions显示文摘 | BELTRAO J COSTA M ROSADO V | 2003 | Geophysical Research Abstracts2003,,5: | 1 |
| 17 | Detection of subclin- ical atherosclerosis in familial hypereholesterolemia using non- invasive imaging modalities 显示文摘 | Caballero P Alonso R Rosado P | 2012 | Atherosclerosis2012,222,2: | 1 |
| 18 | Effect of different operational conditions on biofilm development nitrification and nitrifying microbial population in moving-bed biofilm reactors显示文摘 | BASSIN J P KLEEREBEZEM R ROSADO A S | 2012 | Environmental Science and Technology2012,46,3: | 1 |
| 19 | Effect of ibuprofen on cyclooxygenase and nitric oxide synthase of gastric mucosa:correlation with endoscopic lesions and adverse reactions显示文摘 | Gallego-Sandin S Novalbos J Rosado A | 2004 | Dig Dis Sci2004,49,9: | 1 |
| 20 | New polymorphic micro- satellite markers able to distinguish among Candida parapsilosis sensu stricto isolates 显示文摘 | Sabino R Sampaio P Rosado L | 2010 | J Clin Microbiol2010,48,5: | 1 |