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1Adult-to-adult living-donor liver transplantation: The experience of the Université catholique de Louvain显示文摘Background: Liver transplantation is the treatment for end-stage liver diseases and well-selected malignancies. The allograft shortage may be alleviated with living donation. The initial UCLouvain experience of adult living-donor liver transplantation(LDLT) is presented. Methods: A retrospective analysis of 64 adult-to-adult LDLTs performed at our institution between 1998 and 2016 was conducted. The median age of 29(45.3%) females and 35(54.7%) males was 50.2 years(interquartile range, IQR 32.9–57.5). Twenty-two(34.4%) recipients had no portal hypertension. Three(4.7%) patients had a benign and 33(51.6%) a malignant tumor [19(29.7%) hepatocellular cancer, 11(17.2%) secondary cancer and one(1.6%) each hemangioendothelioma, hepatoblastoma and embryonal liver sarcoma]. Median donor and recipient follow-ups were 93 months(IQR 41–159) and 39 months(22–91), respectively. Results: Right and left hemi-livers were implanted in 39(60.9%) and 25(39.1%) cases, respectively. Median weights of right-and left-liver were 810 g(IQR 730–940) and 454 g(IQR 394–534), respectively. Graft-to-recipient weight ratios(GRWRs) were 1.17%(right, IQR 0.98%-1.4%) and 0.77%(left, 0.59%-0.95%). One-and five-year patient survivals were 85% and 71%(right) vs. 84% and 58%(left), respectively. Oneand five-year graft survivals were 74% and 61%(right) vs. 76% and 53%(left), respectively. The patient and graft survival of right and left grafts and of very small( < 0.6%), small(0.6%–0.79%) and large( ≥0.8%) GRWR were similar. Survival of very small grafts was 86% and 86% at 3-and 12-month. No donor died while five(7.8%) developed a Clavien–Dindo complication IIIa, IIIb or IV. Recipient morbidity consisted mainly of biliary and vascular complications; three(4.7%) recipients developed a small-for-size syndrome according to the Kyushu criteria. Conclusions: Adult-to-adult LDLT is a demanding procedure that widens therapeutic possibilities of many hepatobiliary diseases. The donor procedure can be done safely with low morbidity. The recipient operation carries a major morbidity indicating an important learning curve. Shifting the risk from the donor to the recipient, by moving from the larger right-liver to the smaller left-liver grafts, should be further explored as this policy makes donor hepatectomy safer and may stimulate the development of transplant oncology.Samuele Iesari Milton Eduardo Inostroza Nú?ez Juan Manuel Rico Juri Olga Ciccarelli Eliano Bonaccorsi-Riani Laurent Coubeau Pierre-Fran?ois Laterre Pierre Goffette Chantal De Reyck Beno?t Lengelé Pierre Gianello Jan Lerut 2019Hepatobiliary & Pancreatic Diseases International2019,18,2:5
2Resource-constrained project scheduling: a survey of recent develop-ments显示文摘Herroelen W Reyck B D Demeulemeester E 1998Computers and Operations Research1998,25,4:1
3The multi-mode resource- constrained project scheduling problem with generalized precedence relations 显示文摘DE REYCK B HERROELEN W 1999European Journal of Operational Research1999,119,2:1
4Resource-constrained project scheduling,a survey of recent developments显示文摘Herroelen W De Reyck B Demeuhmeester E 1998Computer & Operations Research1998,25,4:1
5The impact of project portfolio management on information technology projects 显示文摘Bert De Reyck Yael Grushka-Cockayne Martin Lockett etc 2005International Journal of Project Management2005,23,7:1
6Resource-constrained project scheduling:A survey of recent development 显示文摘HERROELEN W DE REYCK B DEMEULEMEESTER E 1998Computers and Operations Research1998,25,4:1
7A hybrid scatter sear-ch/electromagnetism meta-heuristic for the resource-constrained project scheduling problem显示文摘DEBELS D DE REYCK B LEUS R 2006European Journal of Operational Research2006,169,3:1
8The impact of project portfolio management on information technology projects 显示文摘BERT DE REYCK 2005International Journal of Project Management2005,23,2:1
9Resource-constrained project scheduling: a survey of recent developments显示文摘Herroelen W de Reyck B Demenlemeester E 1998Computers & Operations Research1998,25,4:1
10A note on the paper 'resource-constrained project scheduling:notation, classification, models and methods' by Brucker et al显示文摘HERROELEN W S DEMEULEMEESTER E DE REYCK B 2001European Journal of Operational Research2001,128,3:1
11Resource constrained project scheduling:a survey of recent de velopment显示文摘HERROELEN W REYCK B D DEMEULEMEESTER E 1998Computers & Operations Research1998,25,4:1
12Resource constrained project scheduling:a survey of recent developments显示文摘HERROELEN W S DE REYCK B DEMEULEMEESTER E 1998Computers and Operation Research1998,25,4:1
13A hybrid scatter search/electromagnetism meta- heuristic for project scheduling显示文摘Debels D Reyck B D Leus R Vanhoucke M 2006European Journal of Operation Research2006,169,:1
14A hybrid scatter search for the discrete time/resource trade-off problem in project scheduling显示文摘RANJBAR M DE REYCK B KIANFAR F 2009European Journal of Operational Research2009,193,1:1
15Resource-constrained project scheduling: A survey of recent developments 显示文摘Herrolen W Reyck B D Demeulemeester E 1998Computers & Operations Research1998,25,4:1
16A branch-and- bound procedure for the resource - constrained project scheduling problem with generalized precedence relations 显示文摘DE REYCK B HERROELEN W 2000European Journal of Operational Research2000,111,1:1
17A hybrid scatter search electromagnetism meta-heuristic for project sched- uling显示文摘Debels D Reyck B D Leus R 2006European Journal of Operational Research2006,169,2:1
18Resourceconstrained project scheduling: a survey of recent developments显示文摘Herroelen W De Reyck B Demeulemeester E 1998Computers and Operations Research1998,25,4:1
19Milestone payments or royalties? Contract design for R&D licensing显示文摘Crama P Reyck B D Degraeve Z 2008Operations Research2008,56,6:1
20A Hybrid Scatter Search/Electromagnetism Meta-- heuristic for Project Scheduling 显示文摘Dieter D de Reyck B Leus R 2006European Journal of Operational Research2006,169,2:1
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