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| 1 | Nature:死亡的肿瘤细胞释放出胞内钾离子来阻断免疫系统显示文摘在一项新的研究中。来自美国国家癌症研究所和英国巴布拉汉研究所的研究人员发现当肿瘤组织死亡时从它当中泄露出来的一种无机离子起着阻止抗肿瘤免疫细胞发挥功能的作用。这一发现为开发调动免疫系统抵抗癌症的疗法提供一种新的方法。相关研究结果在线发表在Nature期刊上。 | Robert Eil, Suman K. Vodnala, David Clever, Christopher A. Klebanoff, Madhusudhanan Sukumar, Jenny H. Pan, Douglas C. Palmer, Alena Gros, Tori N. Yamamoto, Shashank J. Patel, Geoffrey C. Guittard, Zhiya Yu, David S. Schrump, W. Marston Linehan, Nicholas P. Restifo Christopher A. Klebanoff Valentina Carbonaro, Klaus Okkenhaug, Rahul Roychoudhuri | 2016 | 现代生物医学进展2016，16，31： | 12 |
| 2 | Lineage relationship of CD8^+ T cell subsets is revealed by progressive changes in the epigenetic landscape显示文摘 | Joseph G. Crompton Manikandan Narayanan Suresh Cuddapah Rahul Roychoudhuri Yun Ji Wenjing Yang Shashank J. Patel Madhusudhanan Sukumar Douglas C. Palmer Weiqun Peng Ena Wang Francesco M. Marincola Christopher A. Klebanoff Keji Zhao John S. Tsang Luca Gatt-inoni Nicholas P. Restifo | 2016 | Cellular & Molecular Immunology2016，13，4： | 2 |
| 3 | Does IL-17 promote tumor growth 显示文摘 | Muranski P Restifo NP | 2009 | Blood2009，114，2： | 1 |
| 4 | Antiangiogenic gene therapy of cancer utilizing a recombinant adenovirus to elevate systemic endostatin levels in mice显示文摘 | Feldman AL Restifo NP Alexander HR | 2000 | Cancer Res2000，60，6： | 1 |
| 5 | Adoptive immunotherapy for cancer:harnessing the T cell response 显示文摘 | Restifo NP Dudley ME Rosenberg SA | 2012 | Nat Rev Immunol2012，12，4： | 1 |
| 6 | Less is more: lymphodepletion followed by hematopoietic stem cell transplant augments adoptive T-cell- based anti-tumor immunotherapy显示文摘 | Wrzesinski C Restifo NP | 2005 | Curr Opin Immunol2005，17，2： | 1 |
| 7 | Not so Fas:Re-evaluating the mechanisms of immune privilege and tumor escape 显示文摘 | Restifo NP | 2000 | Nat Med2000，6，5： | 1 |
| 8 | Sorting lhrougb subsets : which T-cell populations mediate highly effective adoptive im- munotherapy? 显示文摘 | Klebanoff CA Gattinoni L Restifo NP | 2012 | J Imnmnother2012，35，9： | 1 |
| 9 | Adoptive cell transfer as personalized immunotherapy for human cancer显示文摘 | Rosenberg SA Restifo NP | 2015 | Science2015，348，6230： | 1 |
| 10 | Cellular constituents of im- mune escape within the tumor microenvironment 显示文摘 | Kerkar SP Restifo NP | 2012 | Cancer Res2012，72，13： | 1 |
| 11 | Suppressors of cytokine signaling (SOCS) in T cell differentiation, maturation, and function 显示文摘 | Palmer DC Restifo NP | 2009 | Trends Immunol2009，30，12： | 1 |
| 12 | DNA and RNA-based vaccines: principles, progress and prospects显示文摘 | Leitner W W Ying H Restifo N P | 2000 | Vaccines2000，18，910： | 1 |
| 13 | Antiangiogenic gene therapy of cancer utilizing a recombinant adenovirus to elevate systemic endostatin levels in mice显示文摘 | Feldman A L Restifo N P Alexander H R | 2000 | Cancer Res2000，，60： | 1 |
| 14 | Cancer immunotherapy:moving beyond current vaccines显示文摘 | Rosenberg S A Yang J C Restifo N P | 2004 | Nat Med2004，10，9： | 1 |
| 15 | Antiangiogenic gene therapy of cancer utilizing a recombinant adenovirus to elevate systemic endostatin levels in mice显示文摘 | Feldman AL Restifo NP Alexander HR | 2000 | Cancer Res2000，60，6： | 1 |
| 16 | Cellular constituents of immune es- cape within the tumor microenvironment 显示文摘 | Kerkar SP Restifo NP | 2012 | Cancer Res2012，72，13： | 1 |
| 17 | Antiangiogenic gene therapy of cancer utilizing a recombinant adenovirus to elevate systemic endostatin levels in mice显示文摘 | Feldman AL Restifo NP Alexander HR | 2000 | Cancer Res2000，60，6： | 1 |
| 18 | Cancer immunotherapy: moving beyond current vaccines 显示文摘 | Rosenberg SA Yang JC Restifo NP | 2004 | Nat Med2004，10，9： | 1 |
| 19 | Antiangiogenic gene therapy of cancer utilizing a recombinant adenovirus to elevate systemic Endostatin levels in mice 显示文摘 | Feldman AL Restifo NP Alexander HR | 2000 | Cancer Res2000，60，： | 1 |
| 20 | Adoptive cell transfer:a clinical path to effective cancer immunotherapy显示文摘 | Rosenberg S A Restifo N P Yang J C | 2008 | Nat Rev Cancer2008，8，4： | 1 |
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