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| 1 | From the Gla domain to a novel small-molecule detector of apoptosis显示文摘Apoptosis 在众多的医药混乱的病原学或致病起一个枢轴的作用,并且这样, apoptotic 房间指向可以实质地推进耐心的照顾。在我们为为 apoptosis 的新奇 low-molecular-weight 探针的探索,我们集中了于不平常的氨基酸纬 - carboxyglutamic 酸(Gla ) ,它在 clotting 因素的绑定起一个重要作用到否定地控告的 phospholipid 表面。基于 Gla 的 alkyl-malonic 酸主题,我们开发了并且现在介绍 ML-10 (2-(5-fluoro-pentyl )-2-methyl-malonic 酸, MW=206 Da ) , apoptosis 的小分子的察觉者的一个新奇家庭的原型的成员。ML-10 被发现在 apoptotic 房间执行选择举起和累积,当从可行或坏死的房间被排除时。有 caspase 激活, Annexin-V 绑定和 mitochondrial 膜潜力的混乱的 apoptotic 特点的 ML-10 举起相互关联。malonate 一半被发现为在 apoptosis 察觉的 ML-10 功能关键。ML-10 在早 apoptosis 对房间的特征的唯一的建筑群作出回应,包括膜潜力,房间膜和细胞质的永久使发酸,和膜正直的保藏的不可逆的损失。ML-10 因此是迄今为止知道的最紧缩的 apoptosis 探查。由于它的氟的符号原子, ML-10 对顺从与 18F 同位素标记收音机,向它为 apoptosis 的临床的正电子排放断层摄影术成像的潜在的未来使用。 | Avi Cohen Anat Shirvan Galit Levin Hagit Grimberg Ayelet Reshef Ilan Ziv | 2009 | Cell Research2009，19，5： | 12 |
| 2 | WS2 nanoflakes from nanotubes for electrocatalysis显示文摘为切开的水的下一代的催化剂向可更新的氢经济是关键的。MoS2 和 WS2 在边地点与高催化的活动代表地球丰富的、高贵金属阴极选择。在他们的开发的一挑战是这些材料到 nanostructure 以便通过另外的边地点的创造完成增加的性能。在这个工作,我们表明一条简单线路用 sonochemical 脱落形成 nanostructured-WS2 在 WS2 nanotubes 打破夹层和 intralayer 契约。产生很少层 nanoflakes 是与边地点的高密度宽的 100 nm。WS2 nanoflakes 为氢进化反应作为阴极被利用(她的) 并且展览上级性能到 WS2 nanotubes 和体积粒子与一个更低的发作潜力,更浅的 Tafel 斜坡和增加的当前的密度。未来工作可以采用进一步改进 electrocatalytic 活动的极端小的 nanoflakes,掺杂物原子,或 graphene 混血儿。 | Charina L. Choi Ju Feng Yanguang Li Justin Wu Alia Zak Reshef Tenne Hongjie Dai | 2013 | Nano Research2013，6，12： | 11 |
| 3 | Synthesis of WS_(2)and MoS_(2)Fullerene-Like Nanoparticles from Solid Precursors显示文摘Inorganic fullerene-like WS_(2)and MoS_(2)nanoparticles have been synthesized using exclusively solid precursors,by reaction of the corresponding metal oxide nanopowder,sulfur and a hydrogen-releasing agent(NaBH4 or LiAlH4),achieved either by conventional furnace heating up to~900℃or by photothermal ablation at far higher temperatures driven by highly concentrated white light.In contrast to the established syntheses that require toxic and hazardous gases,working solely with solid precursors permits relatively safer reactor conditions conducive to industrial scale-up. | Inna Wiesel Hamutal Arbel Ana Albu-Yaron Ronit Popovitz-Biro Jeffrey MGordon Daniel Feuermann Reshef Tenne | 2009 | Nano Research2009，2，5： | 2 |
| 4 | Recent advances in the research of inorganic nanotubes and fullerene-like nanoparticles显示文摘 | Reshef Tenne | 2014 | Frontiers of physics2014，9，3： | 2 |
| 5 | Failure of Synbiotic 2000 to prevent postoperative recurrence of Crohn's disease显示文摘 | CHERMESH I TAMIR A RESHEF R | 2007 | Dig Dis Sci2007，52，： | 1 |
| 6 | Vaccination against autoimmune mouse diabetes with a T cell epitope of the human 65-kDa heat shock protein显示文摘 | Elias D Reshef T Birk OS | 1991 | Proc Natl Acad Sci USA1991，88，8： | 1 |
| 7 | Interleukin-6 and soluble intercellular adhesion molecule-1 in acute brain ischaemia显示文摘 | Orion D Schwammenthal Y Reshef T | 2008 | Eur J Neurol2008，15，4： | 1 |
| 8 | A nonreflecting boundary condition for discrete acoustic and elastic wave equation显示文摘 | Cerjan C Kosloff R Reshef M | 1985 | Geophysics1985，50，： | 1 |
| 9 | Regulation of phosphoenolpyruvate carboxykinase ( GTP ) gene expression 显示文摘 | Hanson R W Reshef L | 1997 | Annu Rev Biochem1997，66，： | 1 |
| 10 | Laparoscopic colectomy for colonic polyps 显示文摘 | Oded Zmora Barak Benjamin Avi Reshef | 2009 | Surg Endosc2009，23，7： | 1 |
| 11 | Detecting Novel Associations inLarge Data Sets显示文摘 | Reshef D N Reshef Y A Finucane H K Grossman S R McVean G Turnbaugh P J | 2011 | Science2011，334，： | 1 |
| 12 | Factors associated with oncologic outcomes after abdominoperineal resection compared with restorative resection for low rectal cancer:patient-and tumor-related or technical factors only?显示文摘 | Reshef A Lavery I Kiran RP | 2012 | Dis Colon Rectum2012，55，1： | 1 |
| 13 | Detecting novel associations in large data sets显示文摘 | Reshef D N Reshef Y A Finucane H K | 2011 | Science2011，334，6062： | 1 |
| 14 | Novel molecular imaging of cell death in experimental cerebral stroke显示文摘 | Reshef A Shirvan A Grimberg H | 2007 | Brain Res2007，1144，4： | 1 |
| 15 | Antihypertensive effect of sweetie fruit in patients with stage Ⅰ hypertension显示文摘 | Reshef N Hayari Y Goren C | 2005 | Am J Hypertens2005，18，10： | 1 |
| 16 | Vaccination against autoim- mune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein显示文摘 | Elias D Reshef T Birk O S | 1991 | Pro Natl Acad Sci1991，88，8： | 1 |
| 17 | Factors associated with oncologic outcomes after abdominoperineal resection compared with restorative resection for low rectal cancer : patient and tumor related or technical factors only显示文摘 | Reshef A Lavery I Kiran RP | 2012 | Dis Col Rec2012，55，1： | 1 |
| 18 | The effects of music relaxation on sleep quality and emotional measures in people living with schizophrenia显示文摘 | Block B Reshef A Vadas L | 2010 | J Music Ther2010，，01： | 1 |
| 19 | Laparoscopic colectomy for colonic polyps显示文摘 | Zomra O Benjamin B Reshef A | 2009 | Surg Enclose2009，23，3： | 1 |
| 20 | Depth migration from irregular surfaces with depth extrapolation methods显示文摘 | Reshef M | 1991 | Geophysics1991，56，1： | 1 |
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