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| 1 | 糖尿病视网膜病变患者玻璃体样本中白细胞介素-8和肿瘤坏死因子-α水平(英文)显示文摘目的:测量糖尿病性视网膜病变(DR)行玻璃体切除术(PPV)患者玻璃体样品中白细胞介素-8(IL-8),肿瘤坏死因子-α(TNF-α)的水平,与对照组比较结果并探讨其对DR的影响。方法:将伊斯坦布尔Bilim大学眼科系的57例(57眼)DR患者和22例黄斑裂孔未伴有增生性玻璃体视网膜病变患者分为研究组和对照组。对所有79例患者行3切口,20G PPV。PPV手术眼内灌注前,用Vitrector抽吸0.5mL玻璃体样品并稀释。样品转至冷藏室,存放在-70℃。IL-8和TNF-α的测量结果用酶联免疫吸附法以pg/mL为单位计算。结果:DR患者玻璃体样本中IL-8水平[82.7891±74.08700(0.08-307.09)pg/mL]明显高于对照组患者[2.9805±3.77546(0.08-18.53)pg/mL](P<0.001)。同样,DR患者TNF-α水平[18.0007±13.90015(2.32-51.11)pg/mL]也显着高于对照组[1.7005±1.26949(0.1-5.17)pg/mL](P<0.001)。结论:在视网膜新生血管形成中起重要作用的TNF-α和作为炎症和血管生成介体的IL-8水平在DR患者玻璃体样本中明显高。 | Rifat Rasier Ozgur Artunay Uzay Gormus Erdal Yuzbasioglu Alper Sengul Amber Senel Kukner Murat Oncel Halil Bahcecioglu | 2013 | 国际眼科杂志2013,13,12: | 8 |
| 2 | Correlation of neutrophil/lymphocyte and platelet/lymphocyte ratio with visual acuity and macular thickness in age-related macular degeneration显示文摘AIM:To investigate the place of neutrophil-to-lymphocyte ratio(NLR) and platelet-to-lymphocyte ratio(PLR) in the diagnosis of and prognosis for neovascular age-related macular degeneration(AMD). METHODS:One hundred AMD patients and 100 healthy controls were included in the study. Blood samples were obtained from the venous blood, which is used for routine analysis, and these samples were subjected to complete blood count. NLR was defined as the neutrophil count divided by the number of lymphocytes, and PLR was defined as the platelet count divided by the number of lymphocytes. RESULTS:No statistically significant difference was observed between the two groups under consideration in terms of demographic features(P>0.05). The average NLR in the patient group was found to be significantly higher than that in the healthy control group(P<0.05). The average PLR was significantly higher in the patient group as compared to the control group(P<0.05). As best corrected visual acuity(BCVA) increased, both NLR and PLR decreased(significant negative correlations at 49.8% and 63.0%, respectively), whereas as central macular thickness(CMT) increased, both NLR and PLR increased(significant positive correlations at 59.3% and 70.0%, respectively).CONCLUSION:NLR and PLR levels are higher among neovascular AMD patients as compared to healthy control group. NLR and PLR levels were found to be inversely proportional to BCVA and directly proportional to CMT. | Elvan Alper Sengul Ozgur Artunay Alev Kockar Ceyda Afacan Rifat Rasier Palmet Gun Nazli Gul Yalcin Erdal Yuzbasioglu | 2017 | International Journal of Ophthalmology(English edition)2017,10,5: | 4 |
| 3 | Corneal tissue welding with infrared laser irradiation after clear corneal incision显示文摘 | Rasier R Ozeren M Artunay O | 2010 | Cornea2010,29,9: | 1 |
| 4 | Incidence and management of acute endophthalmitis after intravitreal bevacizumab(Avastin) injection显示文摘 | Artunay O Yuzbasioglu E Rasier R | 2009 | Eye2009,,: | 1 |
| 5 | The NF-kappaB regulatory network显示文摘 | B rasier AR | 2006 | Cardiovasc Toxicol2006,6,2: | 1 |
| 6 | Vitreous levels of VEGF,IL~8, and TNF-a in retinal detachment 显示文摘 | Rasier R Gormus U Artunay 0 | 2010 | Curr Eye Res2010,35,6: | 1 |
| 7 | The effect of intravitreal bevacizumab(avastin) administration on systemic hypertension显示文摘 | Rasier R Artunay O Yuzbasioglu E | 2009 | Eye2009,23,: | 1 |
| 8 | Ontogenesis and functional aspects of oxytocin and vasopressin gene expression in the thymus network显示文摘 | Hansenne I Rasier G Pequeux C | 2005 | Journal of Neuroimmunology2005,158,: | 1 |
| 9 | Estradiol stimulation of pulsatile gonadotropin-releasing hormone secretion in vitro: correlation with perinatal exposure to sex steroids and induction of sexual precocity in vivo 显示文摘 | Matagne V Rasier G Lebrethon MC Gerard A | 2004 | Endocrinology2004,145,: | 1 |
| 10 | Estradiol stimulation of pulsatile gonadotropin-releasing hormone secretion in vitro: correlation with perinatal exposure to sex steroids and induction of sexual precocity in vivo显示文摘 | Matagne V Rasier G Lebrethon MC | 2004 | Endocrinology2004,145,: | 1 |
| 11 | Early maturation of gonadotropin-releasing hormone secretion and sexual precocity after exposure of infant female rats to estradiol or dichlorodiphenyltrichloroethane 显示文摘 | Rasier G Parent A S Gerard A | 2007 | Biol Reprod2007,77,4: | 1 |
| 12 | Vitreous levels of VEGF, IL-8 ,and TNF-a in retinal detachment显示文摘 | Rasier R Gormus U Artunay O | 2010 | Curr Eye Res2010,35,6: | 1 |
| 13 | Intravitreal bevacizumab in treatment of idiopathic persistent central serous chorioretinopathy: a prospective, controlled clinical study 显示文摘 | Artunay O Yuzbasioglu E Rasier R | 2010 | Curr Eye Res2010,35,: | 1 |
| 14 | Estradiol stimulation of pulsatile gonadotropin releasing hormone secretion in vitro:correlation with perinatal exposure to sex steroids and induction of sexual precocity in vivo显示文摘 | Matagne V Rasier G Lebrethon MC | 2004 | Endocrinology2004,145,6: | 1 |
| 15 | lntravitreal bevacizumab in treatment of idiopathic persistent central serous chorioretinopathy: a prospective, controlled clinical study 显示文摘 | Artunay O Yuzbasioglu E Rasier R el al | 2010 | Curr Eye Res2010,35,2: | 1 |
| 16 | Ontogenesis and functional aspects of oxytocin and vasopressin gene expression in the thymus network 显示文摘 | Hansenne I Rasier G Pequeux C | 2005 | J Neuroimmunol2005,158,12: | 1 |
| 17 | Assessment and mechanism of variations in pubertal timing ininternationally adopted children: a developmental hypothesis 显示文摘 | Domine F Parent AS Rasier G | 2006 | Eur J Edocrinol2006,55,: | 1 |
| 18 | Amniotic membrane welded to contact lens by 1470-nm diode laser:a novel method for sutureless amniotic membrane transplantation显示文摘AIM: To avoid the side effects of the suture usage by welding amniotic membrane(AM) to contact lens(CL)with laser.METHODS: AM was taken from pregnant women and cleaned from blood clots with sterile phosphate-buffered physiological saline solution which included antibiotics.Stromal side of the AM was spread inside of the CL and it was welded to CL by 1470 nm diode laser. And 600 μm diameter fiber tip of the laser was contacted with the epithelial side of the AM from 4 separate points. After welding excess amniotic membrane around the CL was cut with a scalpel.RESULTS: Stromal side of the AM was spread inside of the CL and then with laser fiber, different power levels and exposure times were applied on the epithelium of AM and 340 m W for seven seconds was found optimal.CL and AM attached with the spot welding effect in 4points by touching fiber tip. CL-AM welded complex did not separated from each other while holding AM that extend beyond the CL with the help of two forceps.CONCLUSION: As a conclusion, it was aimed in this study to achieve the success of the conventional amniotic membrane transplantation(AMT) with the easiness of applying a CL and to avoid risks and side effects of corneal or conjunctival suturing. The results showed that the application of the CL-AM complex will be as easy as the application of a CL and lasts shortly. | Rifat Rasier Murat Gulsoy | 2014 | International Journal of Ophthalmology(English edition)2014,7,6: | 1 |
| 19 | Neuroendocrine disruption of pubertal timing and interactions between homeostasis of reproduction and energy balance 显示文摘 | BOURGUIGNON J B RASIER G LEBRETHON M C | 2010 | Molecular and Cellular Endo- crinology2010,324,12: | 1 |
| 20 | Combination treatment with intravitreal injection of ranibizumab and reduced fluence photodynamic secondary to angioid 12-month follow-up显示文摘 | Artunay O Yuzbasioglu E Rasier R | 2011 | therapy for choroidal neovascularization streaks: preliminary clinical results of Retina2011,31,7: | 1 |