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| 1 | Diagnosis of Crohn's disease in India where tuberculosis is widely prevalent显示文摘AIM:To define the parameters that positively predict diagnosis of Crohn's disease (CD) and differentiate it from gastrointestinal tuberculosis (GITB). METHODS:This prospective study over 3 years was carried out in the consecutive Indian patients with definite diagnosis of CD and equal numbers of patients with definite diagnosis of GITB. Demographic, clinical, laboratory, morphological and histological features were noted in all the patients. Serological tests such as p-ANCA, c-ANCA, IgA ASCA and IgG ASCA, were performed. Endoscopic biopsy and/or surgical tissue specimens were subjected to smear and culture for acid-fast bacilli (AFB) and tissue polymerase chain reaction for tuberculosis (TB PCR). Diagnosis of CD and GITB was based on the standard criteria. Data were analyzed using univariate Chi-square test and multiple logistic regression (MLR). RESULTS:The study is comprised of 26 patients with CD (age 36.6 ± 8.6 year, male:female, 16:10) and 26 patients with GITB (age 37.2 ± 9.6 year, male:female, 15:11). The following clinical variables between the two groups (CD vs TB) were significant in univariate analysis:duration of symptoms (58.1 ± 9.8 vs 7.2 ± 3.4 mo), diarrhoea (69.2% vs 34.6%), bleeding per rectum (30.7% vs 3.8%), fever (23.1% vs 69.2%), ascites (7.7% vs 34.6%) and extra-intestinal manifestations of inflammatory bowel disease (61.5% vs 23.1%). Of these, all except ascites and extra-colonic manifestations were found statistically significant by MLR. Accuracy of predicting CD was 84.62% based on the fever, bleeding P/R, diarrhoea and duration of symptoms while it was 63.4% when histology was reported as inflammatory bowel disease and 42.3% when there was recurrence of disease after surgery. Accuracy of predicting GITB was 73.1% when there was co-existing pulmonary lesions and/or abdominal lymphadenopathy;75% when tuberculosis was reported in histology;63.4% when granuloma was found in histology;82.6% when TB PCR was positive;and 61.5% when smear and/ or culture was positive for AFB. Serological test was not useful in differentiation of CD from GITB. Positivity rates for CD and GITB were:p-ANCA-3.8% and 3.8%, c-ANCA-3.8% and 0%, IgA ASCA-38.4% and 23.1%, and IgG ASCA-38.4% and 42.3%, respectively. CONCLUSION:Simple clinical parameters like fever, bleeding P/R, diarrhoea and duration of symptoms have the highest accuracy in differentiating CD from GITB. | Deepak N Amarapurkar Nikhil D Patel Priyamvada S Rane | 2008 | World Journal of Gastroenterology2008,14,5: | 24 |
| 2 | A comprehensive review of extrusion-based additive manufacturing processes for rapid production of metallic and ceramic parts显示文摘The extrusion-based additive manufacturing (EAM) technique is recently being employed for rapid production of metals and ceramic components. This technique involves extruding the metal or ceramic material in solid powder form mixed with a binder (i.e., an expendable viscous fluid), which is removed from the part after 3D printing. These technologies rely on the large design freedom allowed and the cost efficiency advantage over alternative metal additive manufacturing processes that are based on high energy beams, such as laser or electron beams. The EAM of metals and ceramics is not yet widespread, but published scientific and technical literature on it is rapidly growing. However, this literature is still less extensive than that on the fused deposition modeling (FDM) of plastics or the selective laser melting (SLM) of metals. This paper aims at filling this gap. FDM and powder injection molding are identified as preceding or enabling technologies for EAM. This paper systematically reviews all aspects of the feedstock EAM processes used for production of complex-shaped parts. The unique characteristics and advantages of these processes are also discussed with respect to materials and process steps. In addition, the key process parameters are explained to illustrate the suitability of the EAM process for diverse application domains. | Kedarnath Rane Matteo Strano | 2019 | Advances in Manufacturing2019,7,2: | 6 |
| 3 | 女性尿失禁的处理显示文摘本文要点尿失禁大约影响了20%的40岁以上妇女尿失禁可影响生命质量和增加国家医疗服务的经济负担必须强调初级医疗保健机构的作用,因为大多数病人可在此水平得到处理,但也应保证适当的病人转到医院诊治尿失禁的主要病因有尿道括约肌功能下降和膀胱过度活动只有保守治疗失败、准备进行外科手术或排尿困难和神经原性疾病时。 | Ranee Thakar Stuart Stanton 杨勇 | 2004 | 英国医学杂志中文版2004,7,4: | 3 |
| 4 | 有关印度自杀的系统综述(英文)显示文摘背景:自杀是印度重要的死亡原因之一,但基于印度国家犯罪统计局数据估算的自杀率并不可靠。目标:系统回顾现有的有关印度自杀及自杀相关因素的文献。方法:选择适当的检索词在PubMed,PsycINFO,EMBASE,全球健康,谷歌学术和IndMED数据库中查找文献。查找到的论文摘要由两位作者分别独立筛选是否符合纳入标准,再从筛选出的论文全文中摘录标准化数据。结果:本研究筛选出符合纳入标准的36篇论文进行分析。由于抽样过程和研究方法的异质性,荟萃分析的方法不可行。在印度部分农村地区的死因推断研究中报道的自杀率较高,每10万人口中有82至95人自杀,比官方报道的全国自杀率高出8倍。其中20至29岁人群的自杀率最高;30岁以下人群中女性自杀率高于男性,而30岁及以上的人群则正好相反。自缢和服用有机磷农药是最常见的自杀方式,自焚在女性较为常见。社会经济地位低、精神疾病(尤其是酒精滥用)和人际交往障碍是与自杀关系最为密切的因素。结论:有关印度自杀的数据质量非常有限。但显而易见,自杀是一个重要且日益严重的公共卫生问题。相对于高收入国家而言,印度自杀特点为:女性(尤其是年轻妇女)自杀率高于男性、较多选择服用农药的自杀方式、与贫穷因素关系更为紧密而与精神疾病因素相关性较低。 | Anil RANE Abhijit NADKARNI | 2014 | 上海精神医学2014,26,2: | 2 |
| 5 | In vivo toxicity screening programs using metabonomics显示文摘 | Robosky LC Robertson DG Baker DJ Rane S Reily MD | 2002 | Comb Chem High Throughput Screen2002,5,8: | 2 |
| 6 | 挪威海底公路隧道经验——施工、运行、 费用和维护(英文)显示文摘根据2002年关于挪威海底公路隧道的一论文集(挪威公路管理局公路技术部编辑,题目为'论文集98——挪威海底公路隧道',将详细阐述挪威海底隧道的施工建造等经验。挪威第一条海底公路隧道是在1983年通车的,随后建成了另外24条海底公路隧道,至今共有25条海底公路隧道建成通车,总长度达100km。几条新的海底公路隧道目前正在建设中,还有几条则在规划当中,其中最长将达24km。大多数条海底公路隧道是单洞双线,但是当坡度大于6%时,有些隧道就增加一条线。海底公路隧道都位于沿海岸线的干线公路上,以代替原有的繁忙的轮渡,并建立大陆与当地之间的无轮渡连接。据此,主要介绍这些隧道工程中得到的经验,总的来说,海底公路隧道的建设费用逐渐降低,但是各工程间差异很大,各个隧道的运行和维护的费用也相差悬殊,再投资和设备花费也特别高。经验表明,随着渗水量逐年减少,因而抽出渗透水的要求也降低了。介绍了1996年前17条海底隧道中发生的事故和火灾,对19起造成人身伤害的事故进行了分析。其事故发生率极低,只有0.09(每年每一百万车辆每公里发生的事故次数),最高的事发率是在陡坡的年平均日通车量(AADT)低于1500的隧道中。挪威海底隧道中只发生过3起火灾事故,低于交通事故率10%,而这项研究只包括了17条隧道中发生的19起事故。 | HENNING Jan Eirik MELBY Karl фVSTEDAL Erik AMUNDSEN Finn H RANES Guro | 2007 | 岩石力学与工程学报2007,26,11: | 2 |
| 7 | LC and LC–MS/MS studies for the identification and characterization of degradation products of acebutolol显示文摘The aim of the present investigation was to demonstrate an approach involving use of liquid chromatography(LC) and liquid chromatography-mass spectrometry(LC–MS) to separate, identify and characterize very small quantities of degradation products(DPs) of acebutolol without their isolation from the reaction mixtures. The drug was subjected to oxidative, hydrolytic, thermal and photolytic stress conditions as per International Conference on Harmonization(ICH) guideline Q1 A(R2). Among all the stress conditions the drug was found to be labile in hydrolytic(acidic & basic) and photolytic stress conditions, while it was stable in water-induced hydrolysis, oxidative and thermal stress conditions. A total of four degradation products were formed. A C18 column was employed for the separation of all the DPs on a gradient mode by using high-performance liquid chromatography(HPLC). All the DPs were characterized with the help of their fragmentation pattern and the masses obtained upon LC–MS/MS and MSnanalysis. All the hitherto unknown degradation products were identified as 1-(2-(2-hydroxy-3-(isopropylamino)propoxy)-5-(amino)phenyl)ethanone(DP-I), N-(4-(2-hydroxy-3-(isopropylamino)propoxy)-3-acetylphenyl)acrylamide(DP-II), 1-(2-(2-hydroxy-3-(isopropylamino)propoxy)-5-(hydroxymethylamino)phenyl)ethanone(DP-III) and 1-(6-(2-hydroxy-3-(isopropylamino)propoxy)-2,3-dihydro-2-propylbenzo[d]oxazol-5-yl)ethanone(DP-IV). Finally the in-silico carcinogenicity and hepatotoxicity predictions of the drug and all the DPs were performed by using toxicity prediction softwares viz., TOPKAT, LAZAR and Discovery Studio ADMET. The results of in-silico toxicity studies revealed that acebutolol(0.967) and DP-I(0.986) were found to be carcinogenic, while acebutolol(0.490) and DP-IV(0.437) were found to be hepatotoxic. | Uday Rakibe Ravi Tiwari Anand Mahajan Vipul Rane Pravin Wakte | 2018 | Journal of Pharmaceutical Analysis2018,8,6: | 2 |
| 8 | Child characteristics, parenting stress, and parental involvement: Fathers versus mothers 显示文摘 | McBride BA Schoppe SJ Rane TR | 2002 | Journal of Marriage and Family2002,64,4: | 1 |
| 9 | Robotic natural orifice translumenal endo scopic surgery and laparoendoscopic single-site surgery:current status显示文摘 | Rane A Autorino R | 2011 | Curr Opin Urol2011,21,: | 1 |
| 10 | Acute residual ovary syndrome显示文摘 | Rane A Ohizua O | 1998 | AustN Z JObstet Gynecol1998,38,4: | 1 |
| 11 | To stent or not to stent? That is still the question显示文摘 | RANE A CAHILL D LARNER T | 2000 | Endourol2000,14,: | 1 |
| 12 | Studies on traffic accidents in Norwegian road tunnels显示文摘 | Amundsen F H Ranes G | 2000 | Tunneling and Underground Space Technology2000,15,1: | 1 |
| 13 | High temperature index for field evalua tion of heat tolerance in wheat varieties 显示文摘 | Rane J Nagarajan S | 2004 | Agricultural Systems2004,79,2: | 1 |
| 14 | The feasibility of single port laparoscopic cholecystectomy:a pilot study of 20 cases显示文摘 | Rao PP Bhagwat SM Rane A | 2008 | HPB(Oxford)2008,10,5: | 1 |
| 15 | Development of an ex- perimental diet model in rats to study hyperlipidemia and insulin resistance, markers for coronary heart disease 显示文摘 | Munshi RP Joshi SG Rane BN | 2014 | Indian J Pharmacol2014,46,3: | 1 |
| 16 | Efficient Prins cyclization in environmentally benign method using ion exchange re- sin catalyst显示文摘 | More G P Rane M Bhat S V | 2012 | Green Chem Lett Rev2012,5,1: | 1 |
| 17 | Janus kinases : components of multiple signaling pathways 显示文摘 | Rane SG Reddy EP | 2000 | Oncogene2000,19,49: | 1 |
| 18 | Studies on traffic accidents in Norwegian road tunnels显示文摘 | Amundsen F H Ranes G | 2000 | Tunnelling and Underground Space Technology2000,15,1: | 1 |
| 19 | Which is the real goldstandard for small volume renal carcinomas ? Radical nephrectomy versus nephron sparing surgery显示文摘 | MANIKANDAN R SRINIVASAN V RANE A | 2004 | J Endourol2004,18,1: | 1 |
| 20 | Magnetic resonance imaging findings following three different vaginal vault prolapse repair procedures:A randomised study显示文摘 | Rane A Lim YN Withey G | 2004 | Aust N Z J Obstet Gynaecol2004,44,2: | 1 |