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| 1 | Process optimization for microencapsulation of probiotic yeasts显示文摘BACKGROUND: Microencapsulation is a technique which improves the survival and viability ofprobiotics. We demonstrateencapsulation of five potential probiotic yeasts with alginate and gum as encapsulation matrices to improve theirgastrointestinal transit.METHODS: Gum extracted from various cereals viz. rice, oats, barley, finger millet and pearl millet along with alginate havebeen used to encapsulate five potential probiotic yeasts. Screening was carried out by measuring swelling index, encapsulationefficiency and nutritional value of microcapsules encapsulated with alginate and gum. The concentration of OBG, sodiumalginate and inoculum dosage of probiotic yeasts was optimized using response surface methodology (RSM). Efficiency ofalginate OBG microcapsules with or without coating materials viz. whey protein and chitosan also tested. The mucoadhesionability and storage stability of alginate OBG microcapsules with coating materials were tested.RESULTS: Highest encapsulation efficiency of probiotic yeasts was noted using oats bran gum (OBG) microcapsules alongwith alginate in all the five probiotic yeasts. Notably whey protein coated microcapsules showed maximum GIT tolerance(95%) and mucoadhesion (90%) for L. starkeyi VIT-MN03. The minimum loss of viability was observed in L. starkeyi VIT-MN03 microcapsules on 60th day of storage.CONCLUSIONS: This is the first report on optimization and survival of microencapsulated probiotic yeasts under simulatedGIT conditions using natural gum and alginate as encapsulation matrices and whey protein as coating material. | Mangala Lakshmi Ragavan Nilanjana Das | 2018 | Frontiers in Biology2018，13，3： | 2 |
| 2 | Effect of peripheral biopsies in maximising early prostate cancer detection in 8-, 10- or 12-core biopsy regimens显示文摘 | Philip J Ragavan N Desouza J | 2004 | BJU Int2004，93，9： | 1 |
| 3 | Effect of peripheral biopsies in maximizing early prostate cancer detection in 8-, 10-,or 12-core bi-opsy regimens显示文摘 | Philip J Ragavan N Desouza J | 2004 | BJU Int2004，93，9： | 1 |
| 4 | Effect of peripheral biopsies in maximising early prostate cancer detection in 8-,10-or 12-core biopsy regimens显示文摘 | Philip J Ragavan N Desouza J | 2004 | BJU Int2004，93，9： | 1 |
| 5 | Helical CT angiography in evaluation of live kidney donors 显示文摘 | Patil UD Ragavan A Nadaraj | 2001 | Nephrol Dial Transplant2001，16，9： | 1 |
| 6 | Nonlinear stability of ring-stiffened prestressed domes 显示文摘 | RAGAVAN V WOLDE-TINSAE A M | 2000 | Journal of Structural Engineering2000，25，： | 1 |
| 7 | Helical CT angiography inevaluation of live kidney donors 显示文摘 | Patil UD Ragavan A Nadaraj | 2001 | Nephrol Dial Transplant2001，169，： | 1 |
| 8 | Hypoglycemic and antihyperglycemic activity of Nymphaea stellata flowers in normal and alloxan diabetic rats显示文摘 | Rajagopal K Sasikala K Ragavan B | 2008 | Pharm Biol2008，46，9： | 1 |
| 9 | Helical CT angiographyi- nevaluation of live kidney donors 显示文摘 | Patil UD Ragavan A Nadaraj | 2010 | Nephrol DialTr''anSplant2010，16，9： | 1 |
| 10 | SiC/aluminium co-continuous composite synthesized by reactive metal penetration 显示文摘 | Ramesh R Prasanth A S Ragavan M | 2014 | Appl Mech Mater2014，，84： | 1 |
| 11 | Recent developments in the use of layered double hydroxides as host materials for the storage and triggered release of functional anions显示文摘 | Khan A I Ragavan A Fong B | 2009 | Ind Eng Chem Res2009，48，10： | 1 |
| 12 | Synthesis of some novel bioaetive 4-oxy/thio substituted-lH-pyrazol-5 (4H)-ones via efficient cross-Claisen condensation显示文摘 | Ragavan R V Vijayakumar V Kumari N S | 2009 | European Journal of Medicinal Chemistry2009，44，10： | 1 |
| 13 | Effect of peripheral biopsies in maximizing early prostate cancer detection in 8-,10- or 12-core biopsy regimens显示文摘 | Philip J Ragavan N Desouza J | 2004 | BJU Int2004，93，9： | 1 |
| 14 | An algorithm for nonlinear stability analysis of an expandable self-erecting structure 显示文摘 | Vinasithamby Ragavan Amde M Made | 2001 | Computers & Structures2001，79，2930： | 1 |
| 15 | Helical CT angiography in evaluation of live kideny donors显示文摘 | Patil UD Ragavan A Nadaraj | 2001 | Nephrol Dial Transplant2001，16，： | 1 |
| 16 | Using feature construction to improve the performance of neural networks显示文摘 | Piramuthu S Ragavan H -Shaw M J | 1998 | Management Science1998，44，3： | 1 |
| 17 | Surgery in Hashimoto's thyroiditis : indications, complications, and associated cancers显示文摘 | Pradeep PV Ragavan M Ramakrishna BA | 2011 | J Postgrad Med2011，57，2： | 1 |
| 18 | Helical CT angiogra- phy in evaluation of live kidney donors 显示文摘 | Patil UD Ragavan A Nadaraj | 2001 | Nephrol Dial Transplant2001，16，9： | 1 |
| 19 | Chemical Communications显示文摘 | Ragavan K Selvakumar L Thakur M | 2013 | 49(53):59602013，49，53： | 1 |
| 20 | Surgery in Hashimoto's thyroiditis: indications, complications, and associated cancers显示文摘 | Pradeep PV Ragavan M Ramakrishna BA | 2011 | Journal of postgraduate medicine2011，57，2： | 1 |
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