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| 1 | 土地利用对土壤性质影响的区域差异研究显示文摘【目的】研究探讨土地利用对土壤性质影响的区域差异性。【方法】选择4类土地利用方式(天然林、人工林、灌丛和耕地),分别在山西寿阳县和四川丹棱县野外采集土壤样方进行测定,利用统计分析法研究土地利用对土壤性质影响的区域差异。【结果】不同土地利用方式对土壤性质的影响差异显著。人类活动干扰小的土地利用方式的土壤有机质、全氮含量和含盐量等普遍高于人类影响较强的土地利用方式。相同的土地利用方式对土壤性质的影响具有空间差异。即便在相同的土地利用方式下,不同的耕作制度和田间管理措施(灌溉、施肥、农药等)也会造成土壤特性的区域异质性。【结论】不同土地利用方式对土壤性质影响的区域差异揭示了人类活动对环境变化影响的区域差异,可以在一定程度上解释'人-地'的复杂性关系,研究结果可为国家在区域土地规划、作物栽培布局和水土保持政策制订等提供科学依据。 | 吴文斌 杨鹏 唐华俊 Ongaro Luca Shibasaki Ryosuke | 2007 | 中国农业科学2007，40，8： | 69 |
| 2 | 两种NDVI时间序列数据拟合方法比较显示文摘归一化植被指数(NDVI)时间序列数据拟合目的是降低时序数据的噪声水平,重建高质量的NDVI时序数据,有利于多种参数反演和信息提取。针对国际上普遍应用的两种NDVI时间序列数据拟合方法,即Savitzky-Golay滤波法和非对称性高斯函数拟合法,该文在介绍两种方法基本概念的基础上,利用直接比较法和间接比较法在中国对两种拟合方法进行了比较分析。结果表明,Savitzky-Golay滤波法和非对称性高斯函数拟合法的拟合效果总体上一致,但二者之间还是存在区域差异性,这种区域差异与两种方法的自身特点和中国区域自然条件紧密相关。不同数据拟合方法的比较研究可以弄清每种方法的优缺点和区域适宜性,有助于研究人员针对不同研究目的和研究区域选择适宜的NDVI数据拟合方法,减少遥感数据处理中的误差,提高研究精度。 | 吴文斌 杨鹏 唐华俊 周清波 Shibasaki Ryosuke 张莉 | 2009 | 农业工程学报2009，25，11： | 65 |
| 3 | 基于NDVI数据的华北地区耕地物候空间格局显示文摘【目的】探讨基于多时相遥感信息监测中国华北地区耕地种植制度和物候空间格局特征。【方法】选择NDVI时间序列数据,采用非对称性高斯函数拟合方法重建平滑曲线,依据年内NDVI变化曲线峰值数目监测华北地区耕地的多熟种植制度,并利用动态阈值法获取该种植制度下耕地物候空间格局。【结果】华北地区耕地种植制度以一年两熟为主,其分布具有明显的空间差异性,随着纬度递减呈现出从简单到复杂的总体趋势。在该种植制度下,华北地区耕地第一季作物的生长开始期和生长结束期存在十分明显的空间差异,一年两熟区域的第一季作物生长开始期和生长结束期要明显早于一熟区域。与第一季作物物候期明显的空间差异相比,华北地区耕地第二季作物物候期差异不显著。【结论】华北地区耕地种植制度与物候分布格局和自然地理环境紧密相关,不同区域的温度、降水和光照等气候资源的禀赋和匹配程度对该区域的种植结构和作物布局有很大影响。此外,这种耕地物候空间格局还与作物品质、耕作水平、灌溉、施肥和农药等有密切关系。如何区别生态环境因子和人类活动因子对耕地物候的影响是今后值得深入研究的问题。 | 吴文斌 杨鹏 唐华俊 Shibasaki Ryosuke 周清波 张莉 | 2009 | 中国农业科学2009，42，2： | 55 |
| 4 | 四类全球土地覆盖数据在中国区域的精度评价显示文摘该研究以中国耕地类别为研究对象,选择2000年中国土地利用数据(NLCD-2000)为参考数据,利用比较分析法,从面积数量精度和空间位置精度两方面对目前4类全球土地覆盖数据(UMD、IGBP-DISCover、MODIS和GLC2000)产品进行了精度验证,并分析研究了4类数据精度的异同性。结果表明,4类全球数据对中国耕地数量特征和空间位置特征的估测具有明显的区域差异性。MODIS数据集和GLC2000数据集对中国耕地制图的总体精度要高于UMD数据集和IGBP-DISCover数据集。4类数据制图精度高的区域主要分布在中国的农业主产区,而误差大的区域主要分布在中国山区或耕地比例低的区域。低空间分辨率的信息源、基于像元的分类方法,以及中国复杂地形特征是4类全球土地覆盖数据精度差异的主要原因。 | 吴文斌 杨鹏 张莉 唐华俊 周清波 Shibasaki Ryosuke | 2009 | 农业工程学报2009，25，12： | 50 |
| 5 | 基于U型卷积神经网络的航空影像建筑物检测显示文摘经典的卷积神经网络结构在前向传播过程中分辨率不断下降,导致仅采用末层特征时难以实现建筑物边缘的精确分割,进而限制目标检测精度。针对该问题,提出一种基于U型卷积网络的建筑物检测方法。首先借鉴在图像分割领域中性能出色的神经网络模型U-Net的建模思想,采用对称式的网络结构融合深度网络中的高维和低维特征以恢复高保真边界;其次考虑到经典U-Net对位于特征金字塔顶层的模型参数优化程度相对不足,通过在顶层和底层两个不同尺度输出预测结果进行双重约束,进一步提升了建筑物检测精度。在覆盖范围达30km2、建筑物目标28 000余个的航空影像数据集上的试验结果表明,本文方法的检测结果在IoU和Kappa两项关键评价指标的均值上分别达到83.7%和89.5%,优于经典U-Net模型,显著优于经典全卷积网络模型和基于人工设计特征的AdaBoost模型。 | 伍广明 陈奇 Ryosuke SHIBASAKI 郭直灵 邵肖伟 许永伟 | 2018 | 测绘学报2018，47，6： | 45 |
| 6 | 过去20年中国耕地生长季起始期的时空变化显示文摘多时相遥感数据能够较好地描述区域尺度的植被物候和生长季节的变化特征。利用NDVI时序数据,采用非对称性高斯函数拟合方法重建平滑曲线,分别提取了我国20世纪80年代初、90年代初和21世纪初等3个时期为我国耕地第一生长季起始期,计算3个时期平均生长起始期,并分析了我国耕地第一生长季起始期的区域空间分异规律;然后,从区域和省份两个尺度分析了20世纪80年代初至90年代初和20世纪90年代初至21世纪初两个阶段我国耕地生长季起始期动态变化趋势和空间格局。结果表明,我国不同区域耕地第一生长季起始期存在十分明显的空间差异,清楚地呈现出一个从南向北逐渐推迟的空间特征;从不同区域看,在20世纪80年代初至90年代初和20世纪90年代初至21世纪初两个时期,我国耕地第一生长季起始期变化都是提前和推迟并存,不同区域变化程度不一;从不同省份看,在过去20年间,我国绝大多数省份耕地第一生长季起始期都表现为总体提前的趋势,但不同省份的起始期变化具有差异性。影响我国耕地生长季起始期变化的因素很多,如何区别气候变化等自然因子和人类活动因子对耕地生长季起始期变化的影响是一个值得深入研究的问题。 | 吴文斌 杨鹏 唐华俊 周清波 Shibasaki Ryosuke 张莉 唐鹏钦 | 2009 | 生态学报2009，29，4： | 33 |
| 7 | Petawatt and exawatt class lasers worldwide显示文摘In the 2015 review paper‘Petawatt Class Lasers Worldwide’a comprehensive overview of the current status of highpower facilities of>200 TW was presented.This was largely based on facility specifications,with some description of their uses,for instance in fundamental ultra-high-intensity interactions,secondary source generation,and inertial confinement fusion(ICF).With the 2018 Nobel Prize in Physics being awarded to Professors Donna Strickland and Gerard Mourou for the development of the technique of chirped pulse amplification(CPA),which made these lasers possible,we celebrate by providing a comprehensive update of the current status of ultra-high-power lasers and demonstrate how the technology has developed.We are now in the era of multi-petawatt facilities coming online,with 100 PW lasers being proposed and even under construction.In addition to this there is a pull towards development of industrial and multi-disciplinary applications,which demands much higher repetition rates,delivering high-average powers with higher efficiencies and the use of alternative wavelengths:mid-IR facilities.So apart from a comprehensive update of the current global status,we want to look at what technologies are to be deployed to get to these new regimes,and some of the critical issues facing their development. | Colin N.Danson Constantin Haefner Jake Bromage Thomas Butcher Jean-Christophe FChanteloup Enam A.Chowdhury Almantas Galvanauskas Leonida A.Gizzi Joachim Hein David I.Hillier Nicholas W.Hopps Yoshiaki Kato Efim A.Khazanov Ryosuke Kodama Georg Korn Ruxin Li Yutong Li Jens Limpert Jingui Ma Chang Hee Nam David Neely Dimitrios Papadopoulos Rory R.Penman Liejia Qian Jorge J.Rocca andrey A.Shaykin Craig W.Siders Christopher Spindloe Sándor Szatmári Raoul M.G.M.Trines Jianqiang Zhu Ping Zhu Jonathan D.Zuegel | 2019 | High Power Laser Science and Engineering2019，7，3： | 33 |
| 8 | 基于空间模型的全球粮食安全评价显示文摘在综合考虑自然、社会和经济等因子对粮食安全影响的基础上,选择了人均粮食占有量和人均GDP两个指标空间显性评价全球粮食安全状况。为此,本研究构建了3个模型,即空间EPIC模型、作物选择模型和IFPSIM模型,分别模拟作物单产、作物播种面积和作物价格。利用构建的评价框架和模型,以网格大小为6分弧度的地理单元为评价对象,选择水稻、玉米、小麦和大豆等4类全球主要作物类型,以2000年为初始年份,对未来2020年的全球粮食安全状况进行了评价。结果表明,到2020年,多数南亚国家和非洲国家,由于其人均粮食占有量和人均GDP两个指标值都显著降低,粮食供应不足和贫困一起将可能导致该区域存在粮食危机和饥饿风险。对于其他区域,日益增长的粮食需求可以通过本区域的粮食生产自给予以满足,或通过外部购买或粮食进口得到满足,总体上不存在粮食安全问题。为保障未来粮食安全,一方面要保护耕地数量和质量、防止土壤退化、增加资本投入、进行技术创新和升级,提高粮食综合生产能力,保障粮食的有效供给;另一方面加大农业补贴,切实提高农民收入,保障农民利益,增强农业购买力。同时,大力改善粮食流通和农产品贸易体制,通过外部市场来调节粮食供给;积极应对气候变化,提高农业生产对气候变化的适应能力,保证粮食生产的稳定。 | 吴文斌 唐华俊 杨鹏 周清波 陈仲新 Ryosuke SHIBASAKI | 2010 | 地理学报2010，65，8： | 29 |
| 9 | Serum biomarker tests are useful in delineating between patients with gastric atrophy and normal,healthy stomach显示文摘AIM:To study the value of serum biomarker tests to differentiate between patients with healthy or diseased stomach mucosa:i.e.those with Helicobacter pylori(H pylori)gastritis or atrophic gastritis,who have a high risk of gastric cancer or peptic ulcer diseases.METHODS:Among 162 Japanese outpatients,pepsinogen-(Pg-)and(Pg)were measured using a conventional Japanese technique,and the European GastroPanel examination(Pg and Pg,gastrin-17 and H pylori antibodies).Gastroscopy with gastric biopsies was performed to classify the patients into those with healthy stomach mucosa,H pylori non-atrophic gastritis or atrophic gastritis.RESULTS:Pg-and Pg assays with the GastroPanel and the Japanese method showed a highly significant correlation.For methodological reasons,however,serum Pg-,but not Pg,was twice as high with the GastroPanel test as with the Japanese test.The biomarker assays revealed that 5%of subjects had advanced atrophic corpus gastritis which was also verified by endoscopic biopsies.GastroPanel examination revealed an additional seven patients who had either advanced atrophic gastritis limited to the antrum or antrum-predominant H pylori gastritis.When compared to the endoscopic biopsy findings,the GastroPanel examination classified the patients into groups with 'healthy' or 'diseased' stomach mucosa with 94% accuracy,95% sensitivity and 93% specifi city.CONCLUSION:Serum biomarker tests can be used to differentiate between subjects with healthy and diseased gastric mucosa with high accuracy. | Katsunori Iijima Yasuhiko Abe Ryosuke Kikuchi Tomoyuki Koike Shuichi Ohara Pentti Sipponen Tooru Shimosegawa | 2009 | World Journal of Gastroenterology2009，15，7： | 25 |
| 10 | 湖北省南漳/远安动物群特征及其意义初探显示文摘通过资料整理和野外调查,本文认为南漳/远安动物群是产自于嘉陵江组三段顶部纹层状灰岩、微晶灰岩中,以海生爬行动物为特色,伴有大量菌藻类和软体动物的早三叠世奥伦尼克期Spathian晚期的动物群落。该动物群中的海生爬行动物为幻龙类-鱼龙类-汉江蜥-贵州龙-湖北鳄类的组合特征。湖北鳄类相对其他海生爬行动物类型,数量最多,多样性最为丰富。独特的骨骼特征暗示其位于脊椎动物食物链的最低层。大量分异度较高的海生爬行动物在同一群落中出现,暗示在Spathian晚期,海洋生态系统可能已经开始恢复。 | 程龙 阎春波 陈孝红 曾雄伟 Ryosuke Motani | 2015 | 中国地质2015，42，2： | 21 |
| 11 | Prognostic significance of the lymphocyte-to-monocyte ratio in patients with metastatic colorectal cancer显示文摘AIM:To evaluate the prognostic significance of the lymphocyte to monocyte ratio(LMR) in patients with unresectable metastatic colorectal cancer who received palliative chemotherapy.METHODS:A total of 104 patients with unresectable metastatic colorectal cancer who underwent palliative chemotherapy were enrolled. The LMR was calculated from blood samples by dividing the absolute lymphocyte count by the absolute monocyte count. Pretreatment LMR values were measured within one week before the initiation of chemotherapy,while posttreatment LMR values were measured eight weeks after the initiation of chemotherapy.RESULTS:The median pre-treatment LMR was 4.16(range:0.58-14.06). We set 3.38 as the cut-off level based on the receiver operating characteristic curve. Based on the cut-off level of 3.38,66 patients were classified into the high pre-treatment LMR group and 38 patients were classified into the low pretreatment LMR group. The low pre-treatment LMR group had a significantly worse overall survival rate(P = 0.0011). Moreover,patients who demonstrated low pre-treatment LMR and normalization after treatmentexhibited a better overall survival rate than the patients with low pre-treatment and post-treatment LMR values.CONCLUSION:The lymphocyte to monocyte ratio is a useful prognostic marker in patients with unresectable metastatic colorectal cancer who receive palliative chemotherapy. | Masatsune Shibutani Kiyoshi Maeda Hisashi Nagahara Hiroshi Ohtani Katsunobu Sakurai Sadaaki Yamazoe Kenjiro Kimura Takahiro Toyokawa Ryosuke Amano Hiroaki Tanaka Kazuya Muguruma Kosei Hirakawa | 2015 | World Journal of Gastroenterology2015，21，34： | 19 |
| 12 | Biodiversity and Sequence of the Middle Triassic Panxian Marine Reptile Fauna,Guizhou Province,China显示文摘中间的三叠纪的 Panxian 动物志是一个物理标记和在结束以后跟随早三叠纪的停滞阶段的三叠纪的海洋的生态系统的快速的恢复的代表性的记录 -- 二叠的集体扑灭。十海洋的爬行动物税一在 Guanling 形成的上面的成员从 1.82 2.10 m 厚的含化石的水平被发现了,它能在石块爬行动物的 stratigraphic 分布上通过分析被细分进三张海洋的爬行动物床。更低的爬行动物床产出 sauropterygians Placodus inexpectatus 江等, 2008 并且 Lariosaurus hongguoensis 江等, 2006, ichthyopterygians Xinminosaurus catactes 江等, 2008 并且 Phalarodon cf。Phalarodon fraasi Merriam, 1910,与 Mixosaurus panxianensis 江等联系了, 2006,代表 durophagous 的优势的一个阶段税一。在这张床上,大完全的骨骼可以在长度到达多达 2.3 m,并且岩相和 chemostratigraphic 分析在底部,以及升起的海水平附近与 oxic 水环境显示一个相对深的碳酸盐平台。中间的爬行动物床产出 sauropterygian Nothosaurus yangjuanensis 江等, 2006 并且祖龙 Qianosuchus mixtus 李等, 2006,把等与 Mixosaurus panxianensis 江联系了, 2006。在这张床上的石块被它的大头针 cering 出牙和大全面身体尺寸描绘,与最大可能在长度超过 3 m。这张床可能在底部附近与相对缺氧的状况代表最深的盆的一时间。上面的爬行动物床产出 sauropterygians Wumengosaurus delicatomandibularis 江等, 2008, Keichousaurus sp, protorosaur Dinocephalosaurus 东方人是李, 2003,并且 ichthyopterygian Mixosaurus panxianensis 江等, 2006。在这张床上,爬虫税一由吸喂描绘了出现,并且最长是不到 1 m。这张床对应于减少的水深度的一个时期。 | JIANG Dayong Ryosuke MOTANI HAO Weicheng Olivier RIEPPEL SUN Yuanlin Andrea TINTORI SUN Zuoyu Lars SCHMITZ | 2009 | Acta Geologica Sinica(English Edition)2009，83，3： | 17 |
| 13 | Framework of SAGI Agriculture Remote Sensing and Its Perspectives in Supporting National Food Security显示文摘Remote sensing,in particular satellite imagery,has been widely used to map cropland,analyze cropping systems,monitor crop changes,and estimate yield and production.However,although satellite imagery is useful within large scale agriculture applications(such as on a national or provincial scale),it may not supply sufficient information with adequate resolution,accurate geo-referencing,and specialized biological parameters for use in relation to the rapid developments being made in modern agriculture.Information that is more sophisticated and accurate is required to support reliable decision-making,thereby guaranteeing agricultural sustainability and national food security.To achieve this,strong integration of information is needed from multi-sources,multi-sensors,and multi-scales.In this paper,we propose a new framework of satellite,aerial,and groundintegrated(SAGI)agricultural remote sensing for use in comprehensive agricultural monitoring,modeling,and management.The prototypes of SAGI agriculture remote sensing are first described,followed by a discussion of the key techniques used in joint data processing,image sequence registration and data assimilation.Finally,the possible applications of the SAGI system in supporting national food security are discussed. | SHI Yun JI Shun-ping SHAO Xiao-wei TANG Hua-jun WU Wen-bin YANG Peng ZHANG Yong-jun Shibasaki Ryosuke | 2014 | Journal of Integrative Agriculture2014，13，7： | 16 |
| 14 | Characterizing Spatial Patterns of Phenology in Cropland of China Based on Remotely Sensed Data显示文摘This study used time-series of global inventory modeling and mapping studies(GIMMS) normalized difference vegetation index(NDVI) datasets at a spatial resolution of 8 km and 15-d interval to investigate the spatial patterns of cropland phenology in China.A smoothing algorithm based on an asymmetric Gaussian function was first performed on NDVI dataset to minimize the effects of anomalous values caused by atmospheric haze and cloud contamination.Subsequent processing for identifying cropping systems and extracting phenological parameters,the starting date of growing season(SGS) and the ending date of growing season(EGS) was based on the smoothed NVDI time-series data.The results showed that the cropping systems in China became complex as moving from north to south of China.Under these cropping systems,the SGS and EGS for the first growing season varied largely over space,and those regions with multiple cropping systems generally presented a significant advanced SGS and EGS than the regions with single cropping patterns.On the contrary,the phenological events of the second growing season including both the SGS and EGS showed little difference between regions.The spatial patterns of cropping systems and phenology in Chinese cropland were highly related to the geophysical environmental factors.Several anthropogenic factors,such as crop variety,cultivation levels,irrigation,and fertilizers,could profoundly influence crop phenological status.How to discriminate the impacts of biophysical forces and anthropogenic drivers on phenological events of cultivation remains a great challenge for further studies. | WU Wen-bin YANG Peng TANG Hua-jun ZHOU Qing-bo CHEN Zhong-xin Ryosuke Shibasaki | 2010 | Agricultural Sciences in China2010，9，1： | 14 |
| 15 | Postoperative bleeding in patients on antithrombotic therapy after gastric endoscopic submucosal dissection显示文摘AIM To investigated the relationship between postoperative bleeding following gastric endoscopic submucosal dissection(ESD) and individual antithrombotic agents.METHODS A total of 2488 gastric neoplasms in 2148 consecutive patients treated between May 2001 and June 2016 were studied. The antithrombotic agents were categorized into antiplatelet agents, anticoagulants, and other antithrombotic agents, and we included combination therapies [e.g., dual antiplatelet therapy(DAPT)]. The risk factors associated with post-ESD bleeding, namely, antithrombotic agents overall, individual antithrombotic agents, withdrawal or continuation of antithrombotic agents, and bleeding onset period(during the first six days or thereafter), were analyzed using univariate and multivariate analyses.RESULTS The en bloc resection and complete curative resection rates were 99.2% and 91.9%, respectively. Postoperative bleeding occurred in 5.1% cases. Bleeding occurred in 10.3% of the patients administered antithrombotic agents. Being male(P = 0.007), specimen size(P < 0.001), and antithrombotic agent used(P < 0.001) were independent risk factors for postoperative bleeding. Heparin bridging therapy(HBT)(P = 0.002) and DAPT/multidrug combinations(P < 0.001) were independent risk factors associated with postoperative bleeding. The bleeding rate of the antithrombotic agent continuation group was significantly higher than that of the withdrawal group(P < 0.01). Bleeding within postoperative day(POD) 6 was significantly higher in warfarin(P = 0.015), and bleeding after POD 7 was significantly higher in DAPT/multidrug combinations(P = 0.007). No thromboembolic events were reported.CONCLUSION We must closely monitor patients administered HBT and DAPT/multidrug combinations after gastric ESD, particularly those administered multidrug combinations after discharge. | Chiko Sato Kingo Hirasawa Ryonho Koh Ryosuke Ikeda Takehide Fukuchi Ryosuke Kobayashi Hiroaki Kaneko Makomo Makazu Shin Maeda | 2017 | World Journal of Gastroenterology2017，23，30： | 14 |
| 16 | New primitive ichthyosaurian (Reptilia,Diapsida) from the Middle Triassic of Panxian,Guizhou,southwestern China and its position in the Triassic biotic recovery显示文摘一张新原始 ichthyopterygian Xinminosaurus catactes 情报。et sp。nov。在 Panxian 从 Guanling 形成的中间的三叠纪的上面的成员基于一架完全的骨骼被树立,贵州,西南的中国。它在它的出牙,尺骨,腕骨和 tarsals 有特别地导出的人物的一间套房。它类似于在保留伸长的手足骨头的原始 ichthyopterygians。新税在上和多种水兵在 Panxian 动物志的爬行动物是中间的三叠纪的关於生命的放射的物理标记。这动物志的详细研究将在差异,迁居和中间的三叠纪的 ichthyopterygians 的 paleobiogeographic 亲密关系上供应必要知识。 | Dayong Jiang Ryosuke Motani Weicheng Hao Lars Schmitz Olivier Rieppel Yuanlin Sun Zuoyu Sun | 2008 | Progress in Natural Science:Materials International2008，18，10： | 13 |
| 17 | Gastric cancer arising from the remnant stomach after distal gastrectomy:A review显示文摘Gastric stump carcinoma was initially reported by Balfore in 1922,and many reports of this disease have since been published. We herein review previous reports of gastric stump carcinoma with respect to epidemiology,carcinogenesis,Helicobacter pylori(H. pylori) infection,Epstein-Barr virus infection,clinicopathologic characteristics and endoscopic treatment. In particular,it is noteworthy that no prognostic differences are observed between gastric stump carcinoma and primary upper third gastric cancer. In addition,endoscopic submucosal dissection has recently been used to treat gastric stump carcinoma in the early stage. In contrast,many issues concerning gastric stump carcinoma remain to be clarified,including molecular biological characteristics and the carcinogenesis of H.pylori infection.We herein review the previous pertinent literature and summarize the characteristics of gastric stump carcinoma reported to date. | Shinsuke Takeno Tatsuya Hashimoto Kenji Maki Ryosuke Shibata Hironari Shiwaku Ippei Yamana Risako Yamashita Yuichi Yamashita | 2014 | World Journal of Gastroenterology2014，20，38： | 13 |
| 18 | Antibody markers in the diagnosis of inflammatory boweldisease显示文摘Inflammatory bowel disease(IBD), including Crohn's disease and ulcerative colitis, is a chronic intestinal inflammation of unknown etiology. The diagnosis of IBD is based on endoscopic, radiologic and histopathologic criteria. Recently, the search for a noninvasive marker that could augment or replace part of this diagnostic process has become a focus of IBD research. In this review, antibody markers, including microbial antibodies, autoantibodies and peptide antibodies, will be described, focusing on their common features. At present, no single marker with qualities that are satisfactory for the diagnosis and treatment of IBD has been identified, although panels of some antibodies are being evaluated with keen interest. The discovery of novel IBD-specific and sensitive markers is anticipated. Such markers could minimize the use of endoscopic and radiologic examinations and could enable clinicians to implement individualized treatment plans designed to improve the long-term prognosis of patients with IBD. | Keiichi Mitsuyama Mikio Niwa Hidetoshi Takedatsu Hiroshi Yamasaki Kotaro Kuwaki Shinichiro Yoshioka Ryosuke Yamauchi Shuhei Fukunaga Takuji Torimura | 2016 | World Journal of Gastroenterology2016，22，3： | 12 |
| 19 | Safety trial of high-intensity focused ultrasound therapy for pancreatic cancer显示文摘AIM:To evaluate the safety and clinical application of high-intensity focused ultrasound(HIFU)therapy for unresectable pancreatic cancer(PC).METHODS:Thirty PC patients(16 cases in stage III and 14 cases in stage IV)with visualized pancreatic tumors were admitted for HIFU therapy as an optional local therapy in addition to systemic chemotherapy or chemoradiotherapy.Informed consent was obtained.This study began at the end of 2008 and was approved by the ethics committee of our hospital[Institutional Review Board(IRB):890].The HIFU device used was the FEP-BY02(Yuande Bio-Medical Engineering,Beijing,China).RESULTS:The mean tumor size after HIFU therapy changed to 30.9±1.7 mm from 31.7±1.7 mm at pre-therapy.There were no significant changes in tumor size,mean number of treatment sessions(2.7±0.1 mm),or mean total treatment time(2.4±0.1 h).The rate of symptom relief effect was 66.7%.The effectiveness of primary lesion treatment was as follows:complete response,0;partial response,4;stable disease,22;progressive disease,4.Treatment after HIFU therapy included 2 operations,24 chemotherapy treatments,and 4 best supportive care treatments.Adverse events occurred in 10%of cases,namely pseudocyst formation in 2 cases and mild pancreatitis development in 1.However,no severe adverse events occurred in this study.CONCLUSION:We suggest that HIFU therapy is safe and has the potential to be a new method of combination therapy for PC. | Atsushi Sofuni Fuminori Moriyasu Takatomo Sano Fumihide Itokawa Takayoshi Tsuchiya Toshio Kurihara Kentaro Ishii Syujiro Tsuji Nobuhito Ikeuchi Reina Tanaka Junko Umeda Ryosuke Tonozuka Mitsuyoshi Honjo Shuntaro Mukai Mitsuru Fujita Takao Itoi | 2014 | World Journal of Gastroenterology2014，20，28： | 12 |
| 20 | Guanling Biota: A Marker of Triassic Biotic Recovery from the end-Permian Extinction in the Ancient Guizhou Sea显示文摘After a slow recovery from the end-Permian extinction during the Early Triassic and rapid radiation in the Middle Triassic, evolution of organisms reached a new peak phase in the Late Triassic. The Guanling Biota from the Wayao Member (conodont Paragondolella polygnathiformis Zone), Falang Formation, Xinpu, Guanling County, Guizhou Province, southwestern China corresponds to this peak that marks the full recovery from the end-Permian extinction of marine ecosystems. The biota is of high diversity, containing well preserved and completely articulated skeletons of vertebrates comprising marine reptiles, fishes, and invertebrates including crinoids, ammonites, bivalves, and other fossils, and is one of the best examples of marine ecosystem records in life history. The fossil marine reptiles and crinoids are most significant in this biota, especially the marine reptiles, which provide an important link between the Triassic Pacific and Tethys, and between Triassic basal forms and the Jurassic-Cretaceous marine top predators. The most remarkable fossils are the large completely articulated ichthyosaur skeletons up to and more than 10 m, and the first recorded thalattosaurs and placodonts in China. Following our review, of the 17 named reptilian taxa the eight listed here are considered to be valid: three ichthyosaurs (Qianichthyosaurus zhoui Li, 1999; Guizhouichthyosaurus tangae Cao and Luo in Yin et al., 2000, Guanlingsaurus liangae Yin in Yin et al., 2000), three thalattosaurs (Anshunsaurus huangguoshuensis Liu, 1999, Xinpusaurus suni Yin in Yin et al., 2000, Xinpusaurus kohi Jiang et al., 2004), and two placodonts (Sinocyamodus xinpuensis Li, 2000, Psephochelys polyosteoderma Li and Rieppel, 2002). Mixosaurus guanlingensis Cao in Yin et al., 2000 might be a junior synonym of Qianichthyosaurus zhoui Li, 1999, and Cymbospondylus asiaticus Li and You, 2002 and Panjiangsaurus epicharis Chen and Cheng, 2003 might be junior synonyms of Guizhouichthyosaurus tangae Cao and Luo in Yin et al., 2000. It needs to re-describe the holotypes after a complete preparation for clarifying the taxonomic status of Typicusichthyosaurus tsaihuae Yu in Yin et al., 2000, Xinpusaurus bamaolinensis Cheng, 2003, Neosinosaurus hoangi (Zhou in Yin et al., 2000), Wayaosaurus geei Zhou in Yin et al., 2000, Wayaosaurus bellus Zhou in Yin et al., 2000 and Placochelys ? minutus Yin and Luo in Yin et al., 2000. | JIANG Dayong Ryosuke MOTAN LI Chun HAO Weicheng SUN Yuanlin SUN Zuoyu Lars SCHMITZ | 2005 | Acta Geologica Sinica(English Edition)2005，79，6： | 11 |
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