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| 1 | Measurement of liver volume and its clinical significance in cirrhotic portal hypertensive patients显示文摘 | Zhu JY Leng XS Dong N Qi GY Du RY | 1999 | World Journal of Gastroenterology1999,5,6: | 10 |
| 2 | Effect of human autologous serum and fetal bovine serum on human corneal epithelial cell viability,migration and proliferation in vitro显示文摘AIM: To analyze the concentration-dependent effects of autologous serum(AS) and fetal bovine serum(FBS) on human corneal epithelial cell(HCEC) viability, migration and proliferation.METHODS: AS was prepared from 13 patients with nonhealing epithelial defects Dulbecco's modified eagle medium/Ham's F12(DMEM/F12) with 5% FBS, 0.5% dimethyl sulphoxide(DMSO), 10 ng/m L human epidermal growth factor, 1% insulin-transferrin-selenium, then were incubated in serum media: DMEM/F12 supplemented by 5%, 10%, 15% or 30% AS or FBS. HCEC viability was analyzed using cell proliferation kit XTT, migration using a wound healing assay, proliferation by the cell proliferation enzyme-linked immunosorbent assay(ELISA) Brd U kit. Statistical analysis was performed using the generalized linear model, the values at 30% AS or 30% FBS were used as the baselines.RESULTS: HCEC viability was the highest at 30% AS or 15% FBS and the lowest at 10% AS or 30% FBS application. HCEC migration was the quickest through 30% AS or 30% FBS and the slowest through 5% AS or 5% FBS concentrations. Proliferation was the most increased through 15% AS or 5% FBS and the least increased through 30% AS or 30% FBS concentrations. HCEC viability at 10% and 15% AS was significantly worse(P=0.001, P=0.023) compared to baseline and significantly better at 15% FBS(P=0.003) concentrations. HCEC migration was significantly worse(P≤0.007) and HCEC proliferation significantly better(P<0.001) in all concentration groups compared to baseline.CONCLUSION: For the best viability of HCEC 30% AS or 15% FBS, for HCEC migration 30% AS or 30% FBS, for proliferation 15% AS or 5% FBS should be used. Therefore, we suggest the use of 30% AS in clinical practice. | Ming-Feng Wu Tanja Stachon Berthold Seitz Achim Langenbucher Nóra Szentmáry | 2017 | International Journal of Ophthalmology(English edition)2017,10,6: | 7 |
| 3 | Chronic kidney disease severely deteriorates the outcome of gastrointestinal bleeding: A meta-analysis显示文摘AIM To understand the influence of chronic kidney disease(CKD) on mortality, need for transfusion and rebleeding in gastrointestinal(GI) bleeding patients.METHODS A systematic search was conducted in three databases for studies on GI bleeding patients with CKD or endstage renal disease(ESRD) with data on outcomes of mortality, transfusion requirement, rebleeding rate and length of hospitalization(LOH). Calculations were performed with Comprehensive Meta-Analysis software using the random effects model. Heterogeneity was tested by using Cochrane's Q and I2 statistics. Mean difference(MD) and OR(odds ratio) were calculated.RESULTS1063 articles(EMBASE: 589; PubM ed: 459; Cochrane: 15) were found in total. 5 retrospective articles and 1 prospective study were available for analysis. These 6 articles contained data on 406035 patients, of whom 51315 had impaired renal function. The analysis showed a higher mortality in the CKD group(OR = 1.786, 95%CI: 1.689-1.888, P < 0.001) and the ESRD group(OR = 2.530, 95%CI: 1.386-4.616, P = 0.002), and a rebleeding rate(OR = 2.510, 95%CI: 1.521-4.144, P < 0.001) in patients with impaired renal function. CKD patients required more unit red blood cell transfusion(MD = 1.863, 95%CI: 0.812-2.915, P < 0.001) and spent more time in hospital(MD = 13.245, 95%CI: 6.886-19.623, P < 0.001) than the controls.CONCLUSION ESRD increases mortality, need for transfusion, rebleeding rate and LOH among GI bleeding patients. Prospective patient registries and observational clinical trials are crucially needed. | Roland Hágendorn Nelli Farkas Aron Vincze Zoltán Gyongyi Dezso Csupor Judit Bajor Bálint Eross Péter Csécsei Andrea Vasas Zsolt Szakács László Szapáry Péter Hegyi Alexandra Mikó | 2017 | World Journal of Gastroenterology2017,23,47: | 3 |
| 4 | A surgical experience with five hundred thirty liver transplants in the mt显示文摘 | Kamada N Calne RY | 1983 | Surgery1983,93,1: | 2 |
| 5 | Orthotopic liver transplantation in the rat,technique using cuff for portal vein anastomosis and biliary drainage显示文摘 | Kamada N Calne RY | 1979 | Transplantation1979,28,1: | 1 |
| 6 | Orthotopic liver transplantation in the rat: technique using cuff for portal vein anastomosis and biliary draninage 显示文摘 | Kamada N Calne RY | 1979 | Transplantation1979,28,1: | 1 |
| 7 | A surgical experience with five hundred thirty livertransplantation in the raq显示文摘 | Kamada N Calne RY | 1983 | Surgery1983,93,1: | 1 |
| 8 | Ortbotopic liver transplantation in the rat, Technique using cuff for portal vein anastomosis and biliary drainage 显示文摘 | Kamada N Calne RY | 1979 | Transplantation1979,28,1: | 1 |
| 9 | Orthotopic liver transplantation in the rat显示文摘 | Calne RY | 1979 | Transplantation1979,28,: | 1 |
| 10 | A surgical experience with five hundred thirty liver transplants in the rats显示文摘 | Kamada N Calne RY | 1983 | Surgery1983,93,1: | 1 |
| 11 | Central venous catheter tip malposition显示文摘 | RY Patel A Friedman J N Shams earl | 2010 | Journal of Medical Imaging and Radiation Oncology2010,54,1: | 1 |
| 12 | A surgical experience with five hundred thirty liver transplants in the rat显示文摘 | Kamada N Calne RY | 1983 | Surgery1983,93,11: | 1 |
| 13 | A surgical experience with five hundred thirty liver transplants in the rat显示文摘 | Kamada N Calne RY | 1983 | Surgery1983,93,1: | 1 |
| 14 | A surgical experience with five hundred thirty liver transplants in the rat 显示文摘 | Kamada N Calne RY | 1983 | Surgery1983,93,1: | 1 |
| 15 | Orthotopic liver transplantation in the rat : technique using cuff for portal vein anastomosis and biliary drainage显示文摘 | Kamada N Calne RY | 1979 | Transplantation1979,28,1: | 1 |
| 16 | A surgical experience with five hundred thirty liver transplants in the rat显示文摘 | Kamada N Calne RY | 1983 | Surgery1983,93,1: | 1 |
| 17 | Orthotopic liver transplantation in the rat : technique using cuff for portal vein anastomosis and hiliary drainage显示文摘 | Kamada N Calne RY | 1979 | Transplantation1979,28,: | 1 |
| 18 | A surgical experience with five hundred thirty liver transplants in the rat显示文摘 | Kamada N Calne RY | 1983 | Surgery1983,93,11: | 1 |
| 19 | Helicobaeter pylori infection and development of gastric cancer in Korea: long-term follow-up显示文摘 | Kim N Park RY Cho SI | 2008 | J Clin Gastroenterol2008,42,: | 1 |
| 20 | A surgical experience with five hundred thirty liver transplants in the rats 显示文摘 | Kamada N Calne RY | 1983 | Surgery1983,93,1: | 1 |