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	题名	作者	年代	出处	被引量
1	通过手术导致的重量损失由胃绕过在疾病的肥胖的病人改进非含酒精的脂肪肝疾病显示文摘 AIM:To evaluate the effects of surgical weight loss(Roux-en-Y gastric bypass with a modified Fobi-Capella technique) on non alcoholic fatty liver disease in obese patients.METHODS:A group of 26 morbidly obese patients aged 45 ± 2 years and with a body mass index > 40 kg/m 2 who underwent open surgical weight loss operations had paired liver biopsies,the first at surgery and the second after 16 ± 3 mo of weight loss.Biopsies were evaluated and compared in a blinded fashion.The presence of metabolic syndrome,anthropometric and biochemical variables were also assessed at baseline and at the time of the second biopsy.RESULTS:Percentage of excess weight loss was 72.1% ± 6.6%.There was a reduction in prevalence of metabolic syndrome from 57.7%(15 patients) to 7.7%(2 patients)(P < 0.001).Any significance difference was observed in aspartate aminotransferase or alanine aminotransferase between pre and postsurgery.There were improvements in steatosis(P < 0.001),lobular(P < 0.001) and portal(P < 0.05) inflammation and fibrosis(P < 0.001) at the second biopsy.There were 25(96.1%) patients with non alcoholic steatohepatitis(NASH) in their index biopsy and only four(15.3%) of the repeat biopsies fulfilled the criteria for NASH.The persistence of fibrosis(F > 1) was present in five patients at second biopsy.Steatosis and fibrosis at surgery were predictors of significant fibrosis postsurgery.CONCLUSION:Restrictive mildly malabsorptive surgery provides significant weight loss,resolution of metabolic syndrome and associated abnormal liver histological features in most obese patients.	Víctor Vargas Helena Allende Albert Lecube Maria Teresa Salcedo Juan A Baena-Fustegueras José M Fort Joaquín Rivero Roser Ferrer Roberto Catalán Eva Pardina Santiago Ramón y Cajal Jaime Guardia Julia Peinado-Onsurbe	2012	World Journal of Hepatology2012，4，12：	6
2	Do antibioticimpregnated shunts in hydrocephalus therapy reduce the risk of infection? An observational study in 258 patients 显示文摘	RITZ R ROSER F MORGALLA M	2007	BMC Infect Dis2007，7，：	1
3	Tuberculum sellae meningiomas: clinical outcome considering different surgical approaches 显示文摘	Nakamura M Roser F Struck M	2006	Neurosurgery2006，59，5：	1
4	Tuberculum sellae meningioma:Clinical outcome considering different surgical approaches显示文摘	Nakamura M Roser F Struck M	2006	Neurosurgery2006，59，5：	1
5	Outcome of severe lactic acidosis associated with mefformin accumulation 显示文摘	Friesecke S Abe Roser M	2010	Crit Care2010，14，6：	1
6	Aniline mineralization by AOP's 显示文摘	ENRICH B EVA M ROSER S	1998	Applied Catal1998，16，：	1
7	About the prognostic value of Her-2 gene-amplification and cell-proliferation in salivary duct carcinoma of the major salivary glands-a pilot-study显示文摘	Jaehne M Jakel KT Roser K	2001	Laryngorhinootologie2001，80，9：	1
8	Tuberculum sellae meningiomas:clinical outcome considering different surgical approaches显示文摘	Nakamura M Roser F Struck M	2006	Neurosurgery2006，59，5：	1
9	Transition from meningeal melanocytoma to primary cerebral melanoma 显示文摘	Roser F Nakamura M Brandis A	2004	Case report d Neurosurg2004，，：	1
10	Gitelman syn- Jrome显示文摘	Roser M Eibl N Eisenhaber B	2009	Hypertension2009，53，：	1
11	Tuberculum sellae meningiomas:clinieal outcome considering different surgi- cal approaches 显示文摘	Nakamura M Roser F Struck M	2006	Neurosurgery2006，59，5：	1
12	Intraventricular meningiomas: a review of 16 cases with reference to the liter- ature显示文摘	Nakamura M Roser F Bundschuh O	2003	SurgNeurol2003，59，6：	1
13	Meningiomas of the internal auditory canal 显示文摘	Nakamura M Roser F Mirzai S	2004	Neurosurgery2004，55，1：	1
14	Tuberculum sellae meningiomas: clinical outcome considering different surgical approaches 显示文摘	Nakamura M Roser F Struck M	2006	Neurosurgery2006，59，5：	1
15	Tuberculum sellae meningiomas: clinical outcome considering different surgical approaches 显示文摘	Nakamura M Roser F Struck M	2006	Neurosurgery2006，59，5：	1
16	Gitelman syndrome显示文摘	Roser M Eibl N Eisenhaber B		0，，：	1
17	Facial and cochlear nerve function after surgery of cerebellopontine angle meningiomas 显示文摘	Nakamura M Roser F Dormiani M	2005	Neurosurgery2005，57，1：	1
18	Concentrations of polybrominated di- phenyl ethers ,hexachlorobenzenne and polycyclic aromatic hydrocarbons in various foodstuffs before and after cooking显示文摘	Gemma Perell6 Roser Marti - Cid Victoria Castell Juan M Llobet Jose L Domingo	2009	Food and Chemical Toxicology2009，，47：	1
19	Intraoperative auditory brainstem responses in patients with cerebellopontine angle menin- giomas involving the inner auditory canal : analysis of the predictive value of the responses显示文摘	Nakamura M Roser F Dormiani M	2005	J Neurosurg2005，102，4：	1
20	Tuberculum seliae menin-giomas :clinical outcome considering different surgical approaches显示文摘	Nakamura M Roser F Struck M ef al	2006	J Neurosurgery2006，59，：	1

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