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| 1 | Decreased expression of Klotho in cardiac atria biopsy samples from patients at higher risk of atherosclerotic cardiovascular disease显示文摘BackgroundKlotho 蛋白质(α - 并且 β) 是基于膜的传播调整细胞新陈代谢的蛋白质,以及成纤维细胞生长因素(FGF ) 的 lifespan modulating 活动。最近的数据证明了更高的血浆传播 Klotho 层次减少心血管的风险,建议 Klotho 有在心血管的疾病的一个保护的角色。然而,尽管到目前为止它在各种各样的机关被识别了,它是未知的是否,并且高心血管的风险是否能影响 Klotho 的心脏的表示 cardiomyocytes 快车 Klotho 和 FGF , FGF 和另外的 molecules.MethodsWe 与心血管的疾病和 10 匹配年龄的控制使遭到,估计的10年的低风险经历的一名估计的10年的高动脉粥样硬化患者选择了 20 个病人为除冠的动脉以外的原因的心脏的外科绕过。在心肌的活体检视,我们由免疫组织化学评估了 Klotho 和 FGF 是否在 cardiomyocytes 被表示,并且更高心血管的风险是否影响涉及 endoplasmic 蜂窝胃应力的另外的分子的表示,氧化应力,发炎并且 fibrosis.ResultsOnly ,有更高心血管的风险的病人的 cardiomyocytes 显示出 Klotho 的更低的表示,但是 FGF 的更高的表情。而且,更高心血管的风险与增加的表示被联系氧化并且网状的应力,发炎和 fibrosis.ConclusionsThis 学习的 endoplasmic 第一次证明 Klotho 蛋白质在人的 cardiomyocytes 被表示, Klotho 的那心脏的表情在更高心血管的风险病人是下面调整的,当压力相关的分子的表示显著地被增加时。 | Giovanni Corsetti Evasio Pasini Tiziano M Scarabelli Claudia Romano Pratik R Agrawal Carol Chen-Scarabelli Richard Knight Louis Saravolatz Jagat Narula Mario Ferrari-Vivaldi Vincenzo Flati Deodato Assanelli Francesco S Dioguardi | 2016 | Journal of Geriatric Cardiology2016，13，8： | 7 |
| 2 | Determination of surface color of‘all yellow’mango cultivars using computer vision显示文摘Image processing techniques are increasingly applied in sorting applications of agricultural products.This work has assessed the use of image processing for inspecting surface color of two Thai mango cultivars.A computer vision system(CVS)was developed and experiments were conducted to monitor peel color change during the ripening process.Conversion of RGB to CIE-LAB values was done via image processing and prediction models were developed to estimate color parameters from CVS data.Performance evaluations showed insufficient prediction for L values(R2=0.42-0.58),but better results for A and B values(R2=0.90-0.95 and 0.80-0.82,respectively).Compared to the calculated color values hue angle and chroma,a yellowness index computed from intermediate XYZ values was found to be much more adept at accurately predicting peel color from CVS data.Correlations were strong for both cultivars(R2=0.93 for‘Nam Dokmai’and R2=0.95 for‘Maha Chanok’).Results from classification analysis indicated satisfactory results for classifying fruits according to ripeness based on yellowness.Success rates of true positives in the categories unripe,ripe and overripe ranged 72%-92%for‘Nam Dokmai’and 98%-100%for‘Maha Chanok’.Therefore,it was shown that the CVS was capable of producing accurate color values for the two mango cultivars investigated.The findings of this study can be incorporated for development of a robust system for quality prediction and establishment of a CVS for automatic grading and sorting of mangos. | Marcus Nagle Kiatkamjon Intani Giuseppe Romano Busarakorn Mahayothee Vicha Sardsud Joachim Müller | 2016 | International Journal of Agricultural and Biological Engineering2016，9，1： | 5 |
| 3 | Hepatitis C virus-related B cell subtypes in non Hodgkin's lymphoma显示文摘AIM:To evaluate if indolent B cell-non Hodgkin's lymphoma(B-NHL) and diffuse large B-cell lymphoma(DLBCL) in hepatitis C virus(HCV) positive patients could have different biological and clinical characteristics requiring different management strategies.METHODS:A group of 24 HCV related B-NHL patients(11 indolent,13 DLBCL) in whom the biological and clinical characteristics were described and confronted.Patients with DLBCL were managed with the standard of care of treatment.Patients with indolent HCV-related B-NHL were managed with antiviral treatment pegylated interferon plus ribavirin and their course observed.The outcomes of the different approaches were compared.RESULTS:Patients with DLBCL had a shorter duration of HCV infection and a higher prevalence of HCV genotype 1 compared to patients with indolent B-NHL in which HCV genotype 2 was the more frequent genotype.Five of the 9 patients with indolent HCV-relatedB-NHL treated with only antiviral therapy,achieved a complete response of their onco-haematological disease(55%).Seven of the 13 DLBCL patients treated with immunochemotheraphy obtained a complete response(54%).CONCLUSION:HCV genotypes and duration of HCV infection differed between B-NHL subtypes.Indolent lymphomas can be managed with antiviral treatment,while DLBCL is not affected by the HCV infection. | Adriano M Pellicelli Massimo Marignani Valerio Zoli Mario Romano Aldo Morrone Lorenzo Nosotti Giuseppe Barbaro Antonio Picardi Umberto Vespasiani Gentilucci Daniele Remotti Cecilia D'Ambrosio Caterina Furlan Fabrizio Mecenate Ettore Mazzoni Ignazio Majolino Roberto Villani Arnaldo Andreoli Giorgio Barbarini | 2011 | World Journal of Hepatology2011，3，11： | 4 |
| 4 | Monitoring physiological responses to water stress in two maize varieties by infrared thermography显示文摘Water stress is one of the main causes of yield reductions in crops,especially in arid and semi-arid regions where the water supply is limited.Plant water status is frequently assessed by pre-dawn leaf water potential(ΨPD)or leaf stomata conductance(gL)measurements,in support of advanced irrigation scheduling.However,both methods are time and labour consuming.A non-invasive approach to water status detection is the use of infrared thermography(IRT).This experiment was conducted in a greenhouse on two potted maize varieties under irrigated and non-irrigated conditions,and the measurements began when the crop had reached its twelve leaf stage.In order to establish the IRT measurements for detecting the water status of maize,an IRT-based crop water stress index(CWSI)was calculated and compared with simultaneously measuredΨPD and gL data.Good correlations were found between CWSI and gL data(r2=0.71&0.81),as well between CWSI andΨPD data(r2=0.53&0.81).These results highlight the appropriateness of infrared thermal imagery to detect and differentiate between the crop water statuses of different genotypes. | Shamaila Zia Klaus Sophrer Du Wenyong Wolfram Spreer Giuseppe Romano He Xiongkui Joachim Müller | 2011 | International Journal of Agricultural and Biological Engineering2011，4，3： | 3 |
| 5 | Influence of colour changes and moisture content during banana drying on laser backscattering显示文摘Pre-drying treatments are frequently employed to preserve fruit quality.The objective of this research was to monitor colour changes of banana during drying by laser backscattering and to determine the influence of the fruit discolouration on the light distribution into banana tissue.Moreover,to examine the influence of drying on the laser backscatter,the relationship between moisture content and relative laser area of banana slices was analyzed with different degrees of colour degradation.The experiments were conducted at drying air temperature of 63℃with various pre-treatments like chilling,soaking in ascorbic/citric acid and dipping in distilled water.An untreated sample was used as a control.A laser diode emitting at 670 nm with 3 mW power was used as light source.The backscattering relative laser area was used as an indicator for the light absorption into the tissue.The high result achieved on coefficient of determination R^(2)(>0.93)confirmed linear relationship between relative laser area and moisture content.Treatment with ascorbic acid gave the best prediction of the moisture content with the standard error of 5.7 and 8.8 for the estimated intercept and slope.The results showed a significant difference of lightness(L*values)during drying according to the different treatments.As a result,colour degradation did not have a significant influence on the absorption of light at 670 nm wavelength. | Giuseppe Romano Dimitrios Argyropoulos Klaus Gottschalk Emanuele Cerruto Joachim Müller | 2010 | International Journal of Agricultural and Biological Engineering2010，3，2： | 2 |
| 6 | Inhibition of monocyte chemotactic proteins21 synthesis by statins显示文摘 | Romano M Diomede L Sironi M | 2000 | Lab Invest2000，80，7： | 1 |
| 7 | 5-lipoxygenase regulates malignant mesothelial cell survival: involvement of vascular endothelial growth factor 显示文摘 | Romano M Catalano A Nutini M | 2001 | FASEB J2001，15，6： | 1 |
| 8 | Ondansetron inhibits the analgesic effects of tramadol: a possible 5-HT(3) spinal receptor involvement in acute pain in humans 显示文摘 | ARCIONI R DELLA ROCCA M ROMANO S | 2002 | Anesth Analg2002，94，6： | 1 |
| 9 | Function of yeast species and strains in wine flavour 显示文摘 | ROMANO P FIORE C PARAGGIO M | 2003 | Int J Food Microbiol2003，86，2： | 1 |
| 10 | Influence of observational noise on the recurrence quantification analysis显示文摘 | THIEL M ROMANO M C KURTHS J | 2002 | Physica D-Nonlinear Phenomena2002，171，： | 1 |
| 11 | Histologic and histomor-phometric findings from retrieved,immediately occlusally loaded implants in humans显示文摘 | Romanos GE Testori T Degidi M | 2005 | J Periodontol2005，76，11： | 1 |
| 12 | Production of mouse epidermal growth factor in yeast high-level secretion using Pichia pastoris strains containing muhiple gene copies 显示文摘 | CLARE J J ROMANOS M A RAYMENT F B | 1991 | 105:205 - 2121991，105，： | 1 |
| 13 | Inactivation ofauxin in tobacco transformed with the indoleacetic acid-lysine synthetase gene of Pseudomonas savastanoi显示文摘 | Romano C P Hein M B Klee H J | | 0，，03： | 1 |
| 14 | Recurrence plots for the analysis of complex systems显示文摘 | Norbert Marwan M Carmen Romano Marco Thiel | 2007 | Physics Reports2007，438，5： | 1 |
| 15 | Qulity, productivity, and learning in framework-based development:An exploratory case study显示文摘 | Morisio M Romano D and Stamelos I | 2002 | IEEE Trans on Software Engineering2002，28，9： | 1 |
| 16 | Neurobiology of attention-deficit hyperactivity disorder显示文摘 | Renner TJ Gerlach M Romanos M | 2008 | Nervenarzt2008，79，7： | 1 |
| 17 | Foreign gene expression in yeast显示文摘 | Romanos M A Scorer C A Clare J J | 1992 | Yeast1992，8，： | 1 |
| 18 | Low fluenee rate photodynamic therapy combined with intravitreal bevacizumab for neovaseular age-related inacular degeneration显示文摘 | Costagliola C Romano M Rinaldi M | 2010 | Br J Ophthalmol2010，94，2： | 1 |
| 19 | Uncoupling auxin and ethylene effects in transgenic tobacco and Arabidposis plants显示文摘 | Romano C P Cooper M L Klee H J | | 0，，02： | 1 |
| 20 | MiR-494 is regu- lated by ERK1/2 and modulates TRAIL-induced apoptosis in non-small-cell lung cancer through BIM down-regulation 显示文摘 | Romano G Acunzo M Garofalo M | 2012 | Proc Natl Acad Sci USA2012，109，16： | 1 |
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