|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Ursodeoxycholic acid improves gastrointestinal motility defects in gallstone patients显示文摘AIM: To simultaneously evaluate the presence of defects in gallbladder and gastric emptying, as well as in intestinal transit in gallstone patients (GS) and the effect of chronic ursodeoxycholic acid (UDCA) administration on these parameters and on serum bile acids and clinical outcome in GS and controls (CTR). METHODS: After a standard liquid test meal, gallbla-dder and gastric emptying (by ultrasound), oroileal transit time (OITT) (by an immunoenzymatic technique) and serum bile acids (by HPLC) were evaluated before and after 3 mo of UDCA (12 mg/kg bw/d) or placebo administration in 10 symptomatic GS and 10 matched healthy CTR. RESULTS: OITT was longer in GS than in CTR (P < 0.0001); UDCA significantly reduced OITT in GS (P < 0.0001), but not in CTR. GS had longer gastric half-emptying time (t1/2) than CTR (P < 0.0044) at baseline; after UDCA, t1/2 significantly decreased (P < 0.006) in GS but not in CTR. Placebo administration had no effect on gastric emptying and intestinal transit in both GS and CTR. CONCLUSION: The gallstone patient has simultaneous multiple impairments of gallbladder and gastric emptying, as well as of intestinal transit. UDCA administration restores these defects in GS, without any effect in CTR. These results confirm the pathogenetic role of gastrointestinal motility in gallstone disease and suggest an additional mechanism of action for UDCA in reducing bile cholesterol supersaturation. | A Colecchia G Mazzella L Sandri F Azzaroli M Magliuolo P Simoni ML Bacchi-Reggiani E Roda D Festi | 2006 | World Journal of Gastroenterology2006，12，33： | 4 |
| 2 | Development and validation of a sensitive HPLC-ES1-MS/MS method for the direct determination of glucosanline in human plasma显示文摘 | Roda A Sabatini L Barbieri A | 2006 | J Chromatogr B Anglyt Technol Biomed Life Sci2006，844，1： | 1 |
| 3 | Reservoir characterization of the Hollin and Napo Formations, Western Oriente basin, Eeuador显示文摘 | White H J Skopec R A Rodas J A | 1995 | AAPG Memoir1995，62，6： | 1 |
| 4 | Infammatory bowel disease:moving toward a stem cell-based therapy显示文摘 | Lanzoni G Roda G Belluzzi A | 2008 | World J Gastroenterol2008，14，46： | 1 |
| 5 | Current questions for the treatment of advanced gastric cancer显示文摘 | Cervantes A Roda D Tarazona N | 2013 | Cancer Treat Rev2013，39，： | 1 |
| 6 | Separation techniques for bile salts analysis显示文摘 | RODA A PIAZZA F BARALDINI M | 1998 | J Chromatogr B1998，717，12： | 1 |
| 7 | Serpentine aneurysm: regrowth after a superficial temporal artery-middle cerebral ar- tery bypass and internal carotid artery ligation: case report显示文摘 | ISLA A ALVAREZ F RODA JM | 1994 | Neurosurgery1994，34，6： | 1 |
| 8 | Bio - and chemiluminescence in bioanalysis 显示文摘 | Roda A Pasini P Guardigli M | 2000 | Fresenius J Anal Chem2000，366，67： | 1 |
| 9 | The treatment of advanced gastric cancer:current strategies and future perspectives显示文摘 | Cervantes A Rosell S Roda D | 2008 | Ann Oncol2008，，5： | 1 |
| 10 | A rapid and sensitive 384-microtiter wells format chemiluminescent enzyme immunoassay for clenbuterol显示文摘 | Roda A Manetta A C Piazza F | 2000 | Talanta2000，52，2： | 1 |
| 11 | The activation of natural killer cell effector functions by cetuximab-eoated, epidermal growth factor receptor positive tumor cells is enhanced by cytokines 显示文摘 | Roda JM Joshi T Butchar JP McAlees JW Lehman A Tridandapani S | 2007 | Clin Cancer Res2007，13，21： | 1 |
| 12 | Preparation and characterization of ethanol-treated silk fibroin dense membranes for biomaterials application using waste silk fibers as raw material显示文摘 | NOGUEIRA G M RODAS A C D LEITE C A P | 2010 | Bio-Resource Technology2010，101，21： | 1 |
| 13 | The treatment of advanced gastric cancer:current strategies and future per- spectives 显示文摘 | Cervantes A Rosello S Roda D | 2008 | Ann Oncol2008，19，5： | 1 |
| 14 | Nano bioanalytical luminescence:F(o)rster-type energy transfer methods显示文摘 | Roda A Guardigli M Michelini E | 2009 | Anal BioanalChem2009，393，1： | 1 |
| 15 | High performance liquid chromatographic-electrospray mass spectrometric analysis of phenolic acids and aldehydes显示文摘 | Gioaccini A M Roda A Galletti G C | 1995 | J Chromatogr A1995，730，： | 1 |
| 16 | Bio-and chemilumi-nescence imaging in analytical chemistry 显示文摘 | Roda A Guardigli M Pasini P | 2005 | Anal ChirnActa2005，541，12： | 1 |
| 17 | High frequency rail- way vehicle-track dynamics through flexible rotating wheelsets 显示文摘 | Baeza L Fayos J Roda A | | Vehicle System Dynamics0，46，7： | 1 |
| 18 | Analytical approach for monitoring endocrine disrupting compounds in urban waste water treatment plants显示文摘 | RODA A MIRASOLI M MICHELINI E | 2006 | Anal Bio Anal Chem2006，385，： | 1 |
| 19 | Bioluminescence and chemiluminescence in drug screening显示文摘 | Roda A Guardigli M Pasini P | 2003 | Anal Bioanal Chem2003，377，5： | 1 |
| 20 | Separation techniques for bile salts analysis 显示文摘 | Roda A Piazza F Baraldini M | 1998 | J Chromatogr B Biomed Sci Appl1998，717，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员