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| 1 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012，22，1： | 7 |
| 2 | Synthesis and degradation of cytochrome c oxidase subunit mRNAs in neurons: differential bigenomic regulation by neuronal activity显示文摘 | Zhang C Wong Riley M T | 2000 | J Neurosci Res2000，60，3： | 2 |
| 3 | Cytokines and the regulation of apoptosis in reproductive tissues: a review显示文摘 | Lea RG Riley SC Antipatis C | 1999 | Am J Reprod Immunol1999，42，： | 2 |
| 4 | Frequency content of whole body gait kinematic data 显示文摘 | Angeloni C Riley P Krebs D | 1994 | IEEE Transactions on Rehabilitation Engineering1994，2，1： | 1 |
| 5 | 2-D multiple reflections显示文摘 | Riley D C Claerbout J F | 1976 | Geophysics1976，41，4： | 1 |
| 6 | Radiofrefuency tongue base reduction in sleep disordered breathing: A pilot study 显示文摘 | Powell NB Riley RW Guilleminault C | 1999 | Otolargngol Head Neck Surg1999，120，5： | 1 |
| 7 | Lipoxygenase and hydroperoxide lyase activity in ripening tomato fruit显示文摘 | RILEY J C M WILLEMOT C THOMPSON J E | 1996 | Postharvest Biol Technol1996，7，12： | 1 |
| 8 | In-situ neutron diffraction of titanium silicide TisSi3 during self-propagating high-temperature synthesis显示文摘 | Riley D P Oliver C P Kisi E H | 2006 | Intermetallic2006，，14： | 1 |
| 9 | Robot catching: towardsengaging human-humanoid interaction 显示文摘 | RILEY M ATKESON C G | 2002 | AutonomousRobots2002，12，1： | 1 |
| 10 | Pal- atability of beef from steer and young bull car-casses as influenced by electrical stimulation, subcutaneous fat thickness and marbling 显示文摘 | RILEY R R SAVELL J W MURPHEY C E | 1983 | Journal of Animal Science1983，56，3： | 1 |
| 11 | Essential elementsof genetic cancer risk assessment, counseling, and testing:updated recommendations of the National Society of GeneticCounselors 显示文摘 | Riley BD Culver JO Skrzynia C | 2012 | J Genet Couns2012，21，2： | 1 |
| 12 | Expression of Sendai virus nucleocapsid protein in a baculovirus expression system and application to diagnostic assays for Sendai virus infection显示文摘 | Wan C H Riley M I Hook R R Jr | 1995 | J Clin Microbiol1995，33，： | 1 |
| 13 | Key determinants of internal brand management success : An exploratory empirical analysis 显示文摘 | Burmarm C Zeplin S Riley N | 2009 | Journal of Brand Management2009，16，4： | 1 |
| 14 | Estimated genetic parameters for carcass traits of Brahman cattle 显示文摘 | RILEY A C CHASE C C Jr HAMMOND A C | 2002 | Journal of Animal Science2002，80，： | 1 |
| 15 | Cytokines and the regulation of apoptosis in reproductive tissues: a review显示文摘 | Riley S C Antipatis C | 1999 | Am J Reprod Immunol1999，42，2： | 1 |
| 16 | Vitamin A deficiency during rat pregnancy alters placental TNF alpha signalling andapoptosis显示文摘 | ANTIPATIS C ASHWORTH CJ RILEY SC | 2002 | Am J Reprod Immunol2002，47，： | 1 |
| 17 | Assessment of river health: Accounting for perturbation pathways in physical and ecological space显示文摘 | TOWNSEND C R RILEY R H | 1999 | Freshwater Biology1999，41，： | 1 |
| 18 | New project procurement process 显示文摘 | David C Brown Melanie J Ashleigh Michael J Riley etc | 2001 | Journal of Management in Engineering2001，17，4： | 1 |
| 19 | Mechanism of action of Melaleuca alternifolia(tea tree) oil on Staphylococcus aureus determined by time-kill,Lysis,leakage,and salt tolerance assays and electron microscopy显示文摘 | Carson C F Mee B J Riley T V | 2002 | Antimicrob Agents Chemother2002，46，6： | 1 |
| 20 | Radiofrequency tongue base reduction in sleep-disordered breathing:a pilot study显示文摘 | Powell NB Riley RW Guilleminault C | 1999 | Otolaryngol Head Neck Surg1999，120，5： | 1 |
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