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66篇 您的检索式:作者名="RIFAS L"
    题名 作者 年代 出处 被引量
1Accuracy and responses of genomic selection on key traits in apple breeding显示文摘The application of genomic selection in fruit tree crops is expected to enhance breeding eficiency by increasing prediction accuracy,increasing selection intensity and decreasing generation interval.The objectives of this study were to assess the accuracy of prediction and selection response in commercial apple breeding programmes for key traits.The training population comprised 977 individuals derived from 20 pedigreed fllsib families.Historic phenotypic data were available on 10 traits related to productivity and fruit external appearance and genotypic data for 7829 SNPs obtained with an llumina 20K SNP array.From these data,a genome-wide prediction model was built and subsequently used to calculate genomic breeding values of five application fllsib families.The application families had genotypes at 364 SNPs from a dedicated 512 SNP array,and these genotypic data were extended to the high-density level by imputation.These five families were phenotyped for 1 year and their phenotypes were compared to the predicted breeding values.Accuracy of genomic prediction across the 10 traits reached a maximum value of 0.5 and had a median value of 0.19.The accuracies were strongly affected by the phenotypic distribution and heritability of traits.In the largest family,significant selection response was observed for traits with high heritability and symmetric phenotypic distribution.Traits that showed non-significant response often had reduced and skewed phenotypic variation or low heritability.Among the five application families the accuracies were uncorrelated to the degree of relatedness to the training population.The results underline the potential of genomic prediction to accelerate breeding progress in outbred fruit tree crops that still need to overcome long generation intervals and extensive phenotyping costs.Hélène Muranty Michela Troggio Inès Ben Sadok Mehdi Al Rifaï Annemarie Auwerkerken Elisa Banchi Riccardo Velasco Piergiorgio Stevanato W.Eric van de Weg Mario Di Guardo Satish Kumar François Laurens Marco C.A.M.Bink 2015Horticulture Research2015,2,1:14
2Differentiation of human bone marrow osteogenic stromal cells in vitro:induction of the osteoblast phenotype by dexamethasone显示文摘Cheng SL Yang JW Rifas L 1994Endocrinology1994,134,:1
3T-cell cytokine induction of BMP-2 regulates hu- man mesenchymal stromal cell differentiation and mineraliza- tion显示文摘Rifas L 2006J Cell Biochem2006,98,4:1
4Expression of metalloproteinases and issue inhibitors of metalloproteinases in human osteoblast-like cells:dif- ferentiation is associated with repression of metalloproteinase biosynthesis 显示文摘Rifas L Fausto A Scott M J 1994Endocrinology1994,134,2:1
5Inflammatory T cells rapidly induce differentiation of human bone marrow stromal cells into mature osteoblasts显示文摘Rifas L Arackal S Weitzmann N 2001J Cell Bio2001,88,:1
6Differentiation of human bone marrow osteogcnic stromal cells in vitro: induction of the osteoblast phenotype by dexamethasone显示文摘Cheng SL Yang JW Rifas L 1994Endocrinology1994,134,1:1
7Differentiation of human bone marrow osteogenic stromal cells in vitro: Induction of the osteo- blast phenotype by dexamethasone显示文摘Cheng SL Yang JW Rifas L 1994Endocrinology1994,134,1:1
8Pea- nut allergy prevalence among school age children in a US co hort not selected for any disease显示文摘Bunyavanich S Rifas Shiman S L Plat ts Mills T A 2014J Allergy Clin Immunol2014,134,3:1
9T cell activation induces human osteoclast formation via receptor activator of nuclear factor kappaB ligand-dependent and independent mechanisms显示文摘Weitzmann MN Cenci S Rifas L 2001J Bone Miner Res2001,16,:1
10Spontaneous release of interleukin 1 from human blood monocytes reflects bone formation in idiopathic osteoporosis 显示文摘Pacifici R Rifas L Teitelbaum S 1987Proc Natl Acad Sci USA1987,84,:1
11The characterization of human uterine smooth muscle cells in culture显示文摘Rifas L Fant J Makman M H 1979Cell Tissue Res1979,196,3:1
12Differentiation of human bone marrow osteogenic stromal cells in vitro:induction of the osteoblast phenotype by dexamethasone显示文摘Cheng SL Yang JW Rifas L 1994Endocrinology1994,134,1:1
13Expression of metalloproteinases and issue inhibitors of metalloproteinases in human osteoblast-like cells : differentiation is associated with repression of metalloproteinase biosynthesis 显示文摘Rifas L Fausto A Scott M J 1994Endocrinology1994,134,2:1
14Differentiation of human bone marrow osteogenic stromal cells in vitro:induction of the osteoblast phenotype by dexamethasone显示文摘Cheng S Yang JW Rifas L et ol 1994Endocrinology1994,134,1:1
15Expression of metalloproteinases and tissue inhibitors of metalloproteinases in human osteoblast-like cells:differentiation is associated with repression of metalloproteinase biosynthesis显示文摘 FAUSTO A SCOTT MJ 1994Endocrinology1994,134,:1
16T-cell cytokine induction of BMP-2regulates human mesenchymal stromal cell differentiation and mineralization显示文摘Rifas L 2006J Cell Biochem2006,98,4:1
17IL-13 regulates vascular cell adhesion molecule-1 expression in human osteoblasts显示文摘Rifas L Cheng S L 2003J Cell Biochem2003,89,2:1
18A novel T cell cytokine, secreted osteoelastogenie factor of activated T cells, induces osteoelast formation in a RANKL-independent manner 显示文摘Rifas L Weitzmann MN 2009Arthritis Rheum2009,60,:1
19T cells regulate the of matrix metalloproteinasein human osteoblasts via a dual m itogen-activated protein kinasem e c h an ism 显示文摘Rifas L A rack al S A rth ritis R h e u m0,48,4:1
20The role of noggin in human mesenchymal stem cell differentiation显示文摘Rifas L 2007J Cell Bioehem2007,100,4:1
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