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| 1 | Current concepts in total femoral replacement显示文摘Total femoral replacement(TFR) is a salvage arthroplasty procedure used as an alternative to lower limb amputation. Since its initial description in the mid-20^(th) century, this procedure has been used in a variety of oncologic and non-oncologic indications. The most compelling advantage of TFR is the achievement of immediate fixation which permits early mobilization. It is anticipated that TFR will be increasingly performed as the rate of revision arthroplasty rises worldwide. The existing literature is mainly composed of a rather heterogeneous mix of retrospective case series and a wide assortment of case reports. Numerous TFR prostheses are currently available and the surgeon must understand the unique implications of each implant design. Long-term functional outcomes are dependent on adherence to proper technique and an appropriate physical therapy program for postoperative rehabilitation. Revision TFR is mainly performed for periprosthetic infection and the severe femoral bone loss associated with aseptic revisions. Depending on the likelihood of attaining infection clearance, it may sometimes be advisable to proceed directly to hip disarticulation without attempting salvage of the TFR. Other reported complications of TFR include hip joint instability, limb length discrepancy, device failure, component loosening, patellar maltracking and delayed wound healing. Further research is needed to better characterize the long-term functional outcomes and complications associated with this complex procedure. | Deepak Ramanathan Marcelo BP Siqueira Alison K Klika Carlos A Higuera Wael K Barsoum Michael J Joyce | 2015 | World Journal of Orthopedics2015，6，11： | 6 |
| 2 | Role of negative pressure wound therapy in total hip and knee arthroplasty显示文摘Negative-pressure wound therapy(NPWT) has been a successful modality of wound management which is in widespread use in several surgical fields. The main mechanisms of action thought to play a role in enhancing wound healing and preventing surgical site infection are macrodeformation and microdeformation of the wound bed, fluid removal, and stabilization of the wound environment. Due to the devastating consequences of infection in the setting of joint arthroplasty, there has been some interest in the use of NPWT following total hip arthroplasty and total knee arthroplasty. However, there is still a scarcity of data reporting on the use of NPWT within this field and most studies are limited by small sample sizes, high variability of clinical settings and end-points. There is little evidence to support the use of NPWT as an adjunctive treatment for surgical wound drainage, and for this reason surgical intervention should not be delayed when indicated. The prophylactic use of NPWT after arthroplasty in patients that are at high risk for postoperative wound drainage appears to have the strongest clinical evidence. Several clinical trialsincluding single-use NPWT devices for this purpose are currently in progress and this may soon be incorporated in clinical guidelines as a mean to prevent periprosthetic joint infections. | Marcelo BP Siqueira Deepak Ramanathan Alison K Klika Carlos A Higuera Wael K Barsoum | 2016 | World Journal of Orthopedics2016，7，1： | 5 |
| 3 | Control of volatile organic compounds by an AC energized ferroelectric pellet reactor and a pulsed corona reactor显示文摘 | Yamamoto K Ramanathan P A Lawless | 1992 | IEEE Trans Ind Applicat1992，28，2： | 2 |
| 4 | Perturbational profiling of a cell-fine model of tumorigenesis by using metabolic measurements 显示文摘 | Ramanathan A Wang C Schreiber SL | 2005 | Proc Natl Acad Sci USA2005，102，17： | 1 |
| 5 | The Indian Ocean Experiment and the Asian Brown Cloud显示文摘 | RAMANATHAN V CRUTZEN P J MITAR A P | 2002 | Current Science2002，83，： | 1 |
| 6 | Stress analysis & life prediction of a cryogenic rocket engine thrust chamber considering low cycle fatigue 显示文摘 | Asraff A K Muthukumar S S R Ramanathan T J | 2010 | Creep and Thermal Ratchetting2010，，63： | 1 |
| 7 | A case of leukoencephalopathy,cerebral calcifications and cysts显示文摘 | Gulati A Singh P Ramanathan S | 2011 | Ann Indian Acad Neurol2011，14，4： | 1 |
| 8 | Control of volatile organic compounds by an ac energized ferroelectric pellet reactor and a pulsed corona reactor显示文摘 | YamamotoT Ramanathan K Lawless P A | 1992 | IEEE Transactions Industry Application1992，28，5： | 1 |
| 9 | Cathelicidins: Microbicidal activity, mechanisms of action, and roles in in- nate immunity显示文摘 | Ramanathan B Davis E G Ross C R et a l | 2002 | Microb Infect2002，4，： | 1 |
| 10 | A layer-by-Iayer approach to natural polymer-derived bioactive coatings on magnesium alloys显示文摘 | KUNJUNKUNJU S ROY A RAMANATHAN M LEE B CANDIELLO J E KUMTA P N | 2013 | Acta Biomaterialia2013，9，： | 1 |
| 11 | A comparative study of the wear behavior of as-cast and hot extruded ZE41A magnesium alloy 显示文摘 | SELVAN S A RAMANATHAN S | 2010 | Journal of Alloys and Compounds2010，502，2： | 1 |
| 12 | A comparative evaluation of groundwater suitability for irrigation and drinking purposes in two intensively cultivated districts of Punjab, India显示文摘 | Kumar M Kumari K Ramanathan A L | 2007 | Environ Geol2007，53，： | 1 |
| 13 | Progress towards 20% efficiency in Cu(In,Ga)Se2 polycrystalline thin-film solar cell显示文摘 | CONTRERAS M A EGAAS B RAMANATHAN K | 1999 | Progress in Photovoltaics: Research and Applications1999，7，： | 1 |
| 14 | Pert urbational profiling of a cell line model of tumorigenesis by using metabolic measurements显示文摘 | Ramanathan A Wang C Schreiber SL | 2005 | Proc Natl Acad Sci USA2005，102，17： | 1 |
| 15 | Diode characteristics in state-of-the-art ZnO/CdS/Cu(In1-xGax)Se2 solar cells显示文摘 | CONTRERAS M A RAMANATHAN K ABUSHAMA J | 2005 | Progress in Photovoltaics:Research and Applications2005，13，： | 1 |
| 16 | Diode characteristics in state-of-the-art ZnO/CdS/Cu (In1-xGax ) Se2 solar cells显示文摘 | Contreras Miguel A Ramanathan K AbuShama J | 2005 | Prog Photovolt: Res Appl2005，13，： | 1 |
| 17 | Phase Ⅱ study of gemcitabine and erlotinib as adjuvant therapy for patients with resected pancreatic cancer显示文摘 | Bao PQ Ramanathan RK Krasinkas A | 2011 | Ann Surg Oncol2011，18，4： | 1 |
| 18 | Functional- ized graphene sheets for polymer nanocomposites显示文摘 | Ramanathan T Abdala A A Stankovich S | 2008 | Nature Nanotechnology2008，，3： | 1 |
| 19 | Distribution of rare earth elements and heavy metals in the surficial sediments of the Himalayan river system显示文摘 | RAMESH R RAMANATHAN A L RAMESH S | 2000 | Geochemical Journal2000，34，： | 1 |
| 20 | Functionalized graphene sheets for polymer nanocomposites显示文摘 | Ramanathan T Abdala A A Stankovich S | 2008 | Nature Nanotechn2008，3，： | 1 |
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