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| 1 | Serum complement C4a and its relation to liver fibrosis in children with chronic hepatitis C显示文摘AIM:To evaluate serum complement C4a and its relation to liver fibrosis in children with chronic hepatitis C virus(HCV)infection.METHODS:The study included 30 children with chronic HCV infection before receiving antiviral therapy.Chronic HCV infection was defined by positive anti-HCV,a positive polymerase chain reaction for HCV-RNA for more than 6 mo with absence of any associated liver disease.A second group of 30 age-and sex-matched healthy children served as controls.Serum C4a levels were measured by enzyme-linked immunosorbent assay.Liver fibrosis stage and inflammatory grade were assessed using Ishak scoring system.Serum C4a levels were compared according to different clinical,laboratory and histopathological parameters.Statistical significance for quantitative data was tested by MannWhitney U non-parametric tests.For qualitative data,significance between groups was tested by 2test.Correlation was tested by Spearman’s test.Results were considered significant if P value≤0.05.RESULTS:The age of the patients ranged from 3.5to 18 years and that of controls ranged from 4 to 17years.C4a mean levels were merely lower in patients(153.67±18.69 mg/L)than that in the controls(157.25±11.40 mg/L)with no statistical significance(P=0.378).It did not differ significantly in patients with elevated vs those with normal transaminases(152.25±16.62 vs 155.36±21.33;P=0.868)or with different HCV viremia(P=0.561).Furthermore,there was no statistical significant difference in serum levels between those with no/mild fibrosis and those with moderate fibrosis(154.65±20.59 vs 152.97±17.72;P=0.786)or minimal and mild activity(155.1±21.93 vs 152.99±17.43;P=0.809).Though statistically not significant,C4a was highest in fibrosis score 0(F0),decreasing in F1 and F2 to be the lowest in F3.When comparing significant fibrosis(Ishak score≥3)vs other stages,C4a was significantly lower in F3 compared to other fibrosis scores(143.55±2.33 mg/L vs 155.26±19.64 mg/L;P=0.047)and at a cutoff value of less than 144.01 mg/L,C4a could discriminate F3 with 76.9%sensitivity and75%specificity from other stages of fibrosis.CONCLUSION:Serum complement C4a did not correlate with any of transaminases,HCV viremia or with the histopathological scores.Although C4a decreased with higher stages of fibrosis,this change was not significant enough to predict individual stages of fibrosis.Yet,it could predict significant fibrosis with acceptable clinical performance. | Behairy E Behairy Ghada M El-Mashad Ragab S Abd-Elghany Enas M Ghoneim Mostafa M Sira | 2013 | World Journal of Hepatology2013，5，8： | 4 |
| 2 | 对由磁性的回声成像的灰色的事 heterotopia 的评价显示文摘 AIM:To evaluate magnetic resonance imaging(MRI) features of different types of gray matter heterotopia.METHODS:Between June 2005 and December 2009,the medical records and MRI studies of patients with gray matter heterotopia were reviewed.The MRI morphologic findings of heterotopia were recorded along with the presence and type of associated cranial malformations.Available clinical and electrophysiological data were also recorded.RESULTS:20 patients were included in the study.Their ages ranged from 9 mo to 39 years with a mean age of 15 years.All patients suffered from epileptic seizures.According to the location of heterotopia,patients were classified into three groups:subependymal(12),subcortical(5) and band(3) heterotopia.CONCLUSION:MRI was useful in diagnosing and differentiating between various types of gray matter heterotopia.The severity of clinical manifestations of heterotopia was related to the location and pattern of heterotopia.Determination of heterotopia type and its extent is useful for management planning and predicting prognosis. | Ragab H Donkol Khaled M Moghazy Alaeddin Abolenin | 2012 | World Journal of Radiology2012，4，3： | 4 |
| 3 | Construction of sorghum RFLP linkage map using sorghum and maize DNA probes显示文摘 | Ragab R A Dronavalli S Saghai Maroof M A and Yu Y G | 1994 | Genome1994，37，： | 1 |
| 4 | The use of single versus double dose of intra- vaginal prostaglandin E2' misoprostol' prior to abdominal myomectomy: a randomized controlled clinical trial显示文摘 | Ragab A Khaiary M Badawy A | 2014 | J Reprod Infer- til2014，15，3： | 1 |
| 5 | An expertsystem for multiobjective decisionmak- ing:application of fuzzy linguistic preferences and goal programming显示文摘 | Rasmy M H Lee S M Abd El-Wahed W F Ragab A M El-Sherbiny M M | 2002 | Fuzzy Sets and Systems2002，127，2： | 1 |
| 6 | The chemical composition of the juice and seeds of pomegranate fruits 显示文摘 | EI-Nemr S E Ismail I A Ragab M | 1992 | Fluessiges Obst (Fruit Processing)1992，9，11： | 1 |
| 7 | The determinant and adjoint of a square fuzzy matrix显示文摘 | Ragab M Z Emam E G | 1994 | Fuzzy Sets and Systems1994，61，： | 1 |
| 8 | Effect of irrigation me- thods, management and salinity of irrigation water on tomato yield, soil moisture and salinity distribution显示文摘 | Malash N M Flowers T J Ragab R | 2008 | Irrigation Science2008，26，4： | 1 |
| 9 | Soluble cy- tokeratin-19 and E-selectin biomarkers: their relevance for lung cancer detection when tested independently or in combinations 显示文摘 | Swellam M Ragab HM Abdalla NA | 2008 | Cancer Biomark2008，4，1： | 1 |
| 10 | On the Min-max Composition of Fuzzy Matrices显示文摘 | Ragab M Z Emam E G | 1995 | Fuzzy Sets and Systems1995，，75： | 1 |
| 11 | Acquisition and short-term retention of inhaler techniques require intact executive function in elderly subjects显示文摘 | Allen SC Jain M Ragab S | 2003 | Age Ageing2003，32，： | 1 |
| 12 | Effect of fire on flexural behavior of RC beams显示文摘 | EI-Hawary M Ragab A EI-Azim A | 1996 | Construction and Building Materials1996，10，14： | 1 |
| 13 | Effect of fire on shear behavior of RC beams显示文摘 | EI-HAWARY M M RAGAB A M EI-AZIM A | 1997 | Computer & Structure1997，65，2： | 1 |
| 14 | Effect of fire on flexural behavior of RC beams显示文摘 | EI-HAWARY M M RAGAB A M EI-AZIM A | 1996 | Computer & Structure1996，10，2： | 1 |
| 15 | CYFRA21-t : an indica- tor of survival and therapeutic effect in lung cancer显示文摘 | Swellam M Ragab HM Abdalla N | 1997 | Oncology1997，54，1： | 1 |
| 16 | Evaluation of the medical and surgical treatment of chronic rhinosinusitis: a prospective, randomised, controlled trial显示文摘 | RAGAB S M LUND V J SCADDING G | 2004 | Laryngoscope2004，114，： | 1 |
| 17 | On the min-max composition of fuzzy ma trices显示文摘 | Emam E G | 1995 | Fuzzy Sets and Systems1995，75，： | 1 |
| 18 | Evaluation of the medical and surgical treatment of chronic rhinosinusitis: a prospective, randomised, controlled trial 显示文摘 | Ragab S M Lund V J Scadding G | 2004 | Laryngo- scope2004，114，5： | 1 |
| 19 | Fractionation,solubility and functional properties of cowpea (Vignaunguiculata) proteins as affected by pH and/or salt concentration显示文摘 | Ragab DiaelDin M Babiker Elfadil E Eltinay Abdullahi H | 2004 | Food Chemistry2004，84，： | 1 |
| 20 | No- vel benzimidazole-pyrimidine conjugates as potent antitu-mor agents显示文摘 | H T Abdel-Mohsen F A F Ragab M M Ramla | 2010 | Eur J Med Chem2010，45，6： | 1 |
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