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| 1 | Cross-kingdom inhibition of breast cancer growth by plant miR159显示文摘MicroRNAs (miRNAs ) 是基因表示的批评管理者,并且在优核质的开发,生理学,和疾病施加广泛的影响。并行的高度在植物和动物在 miRNA 生物的续生说和行动的分子的基础被发现。最近的研究有趣地建议导出植物的 miRNAs 的一个潜在的跨王国的行动,通过饮食的吸入,在调整哺乳动物的基因表示。尽管在哺乳动物的标本检测的植物 miRNAs 的来源和范围仍然保持争论,这些起始的研究鼓舞了我们决定植物 miRNAs 是否能在西方的人的 sera 被检测并且这些植物 miRNAs 是否能影响与象癌症那样的人的疾病有关的基因表示和细胞的过程。这里,我们发现西方的施主 sera 包含了植物 miRNA miR159,其在浆液的丰富相反地在病人与乳癌发生和前进被相关。在人的 sera, miR159 主要在细胞外的泡被检测,并且对在 3 ′ 上建议发源植物的 2'-O-methylation 的钠 periodate 氧化抵抗;终端核糖。在乳癌房间然而并非非癌的乳房的上皮的房间,一合成 miR159 模仿能够由指向编码表明抄写因素的 Wnt 的 TCF7 禁止增长,在 MYC 蛋白质层次导致减少。miR159 的口头的管理显著地模仿在老鼠压制了异种皮移植胸肿瘤的生长。这些结果第一次证明植物 miRNA 能在哺乳动物禁止癌症生长。 | Andrew R Chin Miranda Y Fong George Somlo Jun Wu Piotr Swiderski Xiwei Wu Shizhen Emily Wang | 2016 | Cell Research2016，26，2： | 35 |
| 2 | Structure properties of hydroxyapatite obtained by mechanosynthesis 显示文摘 | Silva C C Pinheiro A G Miranda M A R | 2003 | Solid State Sciences2003，5，： | 1 |
| 3 | Characteriza- tion of Fiber Laser Welds in X100 Pipeline Steel 显示文摘 | Miranda R Costa A Quintino L | 2009 | Materials and Design2009，30，7： | 1 |
| 4 | 'Edge effect' of (32)P radioactive stents is caused by the combination of chronic stent injury and radioactive dose falloff显示文摘 | Willem J Evelyn R Miranda S | 2001 | Circulation2001，104，： | 1 |
| 5 | Incorporating inventory control decisions into a strategic distribution network design model with stochastic demand 显示文摘 | Miranda P A Garrido R A | 2004 | Transportation Research Part E2004，40，： | 1 |
| 6 | Antibiotic resistant bacteria in fish from the Concepcion Bay,Chile显示文摘 | C D Miranda R Zemelman | 2001 | Marine Pollution i3ul- letin2001，42，11： | 1 |
| 7 | Incorporating Inventory Control Decisions into a Strategic Distribution Network Design Model with Stochastic Demand 显示文摘 | Miranda P A Garrido R A | 2004 | Transportation Research Part E2004，，40： | 1 |
| 8 | MicroRNA-21 knockdown disrupts gfioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas显示文摘 | Corsten MF Miranda K kasmich R | 2007 | Cancer Res2007，67，19： | 1 |
| 9 | Semivariogram textural classification of JERS-1(FUYO-1) SAR data obtained over a flooded area of the Amazonian rainforest显示文摘 | Miranda F P Fonseca L E N Carr J R | 2000 | International Journal of Remote Sensing2000，19，3： | 1 |
| 10 | MicroRNA-21 knockdown disrupts glioma Growth in vivo and displays synergistic cytotoxicity with neural precursor cell-deliv- ered S-TRAIL in human gliomas 显示文摘 | Corsten MF Miranda R Kasmieh R | 2007 | Cancer Res2007，67，19： | 1 |
| 11 | Selective suppres- sion of late laryngeal adductor responses by N-methyl-D- aspartate receptor blockade in the cat显示文摘 | Ambalavanar R Purcell L Miranda M | 2002 | J Neurophysiol2002，87，3： | 1 |
| 12 | Curing temperature effect on smokeless fuel briquettes prepared with molasses and H3 PO4 显示文摘 | Blesa M J Miranda J L Moliner R | 2003 | Fuel2003，82，13： | 1 |
| 13 | A Simultaneous Inventory Control and Facility Location Model with Stochastic Capacity Constraints显示文摘 | Miranda P A Garrido R A | 2006 | Networks and Spatial Economics2006，，6： | 1 |
| 14 | Lymphomas involving the breast:a study of 106 cases comparing localized and disseminated neoplasms显示文摘 | Talwalkar S S Miranda R N Valbuena J R | | 0，，09： | 1 |
| 15 | Canine parvovirus 2c infection in a cat with severe clinical disease显示文摘 | Miranda C Parrish C R Thompson G | 2014 | J Vet Diagn Invest2014，26，3： | 1 |
| 16 | A bifunctional TPS- TPP enzyme from yeast confers tolerance to multiple and extreme abiotic-stress conditions in transgenic Arabidopsis显示文摘 | Miranda J A Avonce N Suarez R | 2007 | Planta2007，226，6： | 1 |
| 17 | Structure properties of hydroxyapatite obtained by mechanosynthesis 显示文摘 | Silva CC Pinheiro A G Miranda M A R | 2003 | Solid StateSci2003，5，3： | 1 |
| 18 | Discipline styles in families with children with attention deficit hyperactivity disorder: their influence on the course of the disorder 显示文摘 | Miranda Casas A Grau Sevilla D Marco Taberner R | 2007 | Rev Neurol2007，44，2： | 1 |
| 19 | Identification of Recalcitrant Stickles and Their Sources in Newsprint Production 显示文摘 | Miranda R Balea A De La Blanca E S | 2008 | Industrial and Engineering Chemistry Research2008，47，16： | 1 |
| 20 | Laparoscopic cholecystectomy as an outpatient procedure显示文摘 | Lam D Miranda R Horn SJ | 1997 | J Am Coil Surg1997，185，2： | 1 |
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