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| 1 | Current view of the immunopathogenesis in inflammatory bowel disease and its implications for therapy显示文摘Although the aetiology of inflammatory bowel disease (IBD) remains unknown, the pathogenesis is gradually being unravelled, seeming to be the result of a combination of environmental, genetic, and immunological factors in which an uncontrolled immune response within the intestinal lumen leads to inflammation in genetically predisposed individuals. Multifactorial evidence suggests that a defect of innate immune response to microbial agents is involved in IBD. This editorial outlines the immunopathogenesis of IBD and their current and future therapy. We present IBD as a result of dysregulated mucosal response in the intestinal wall facilitated by defects in epithelial barrier function and the mucosal immune system with excessive production of cytokines growth factors, adhesion molecules, and reactive oxygen metabolites, resulting in tissue injury. Established and evolving therapies are discussed in the second part of this editorial and at the end of this section we review new therapies to modulate the immune system in patients with IBD. | MI Torres A Ríos | 2008 | World Journal of Gastroenterology2008,14,13: | 18 |
| 2 | Risk factors of acute renal failure after liver transplantation显示文摘 | Cabezuelo JB Ramírez P Ríos A | 2006 | Kidney International2006,,06: | 1 |
| 3 | Results after treatment of traumat-ic knee dislocations:A report of 26 cases显示文摘 | Ríos A Villa A Fahandezh H | | 0,,: | 1 |
| 4 | Supercritical fluid extraction as an on-line clean up technique for determination of riboflavin vitamins in food sample by capillary electrophoresis with fluorimetric detection显示文摘 | Zougagh M Ríos A | 2008 | Electrophoresis2008,29,15: | 1 |
| 5 | New aspects in celiac disease显示文摘Celiac disease (CD) is a common autoimmune disorder characterized by an immune response to ingested gluten and has a strong HLA association with HLA- DQ2 and HLA-DQ8 molecules, but human HLA-DQ risk factors do not explain the entire genetic susceptibility to gluten intolerance. CD is caused by the lack of immune tolerance (oral tolerance) to wheat gluten. In this sense, the expression of soluble HLA-G in CD is of special interest because the molecule plays an important role in the induction of immune tolerance. The enhanced expression of soluble HLA-G found in CD may be part of a mechanism to restore the gluten intolerance. In this editorial, we review recent progress in understanding CD in relation to its prevalence, diagnosis and possible mechanisms of pathogenesis. | MI Torres MA López Casado A Ríos | 2007 | World Journal of Gastroenterology2007,13,8: | 10 |
| 6 | Spanish and Latin American nursing personnel and deceased organ donation:a study of attitude显示文摘 | A Ríos L Martínez-Alarcón MA Ayala | | 0,,01: | 1 |
| 7 | Welsh citizens in South-Eastern Spain:a study of attitude toward organ donation显示文摘 | A Ríos L Martínez-Alarcón J Sánchez | | 0,,05: | 1 |
| 8 | Information received by secondary school teaching personnel about organ donation and transplantation:a study in the southeast of Spain显示文摘 | Febrero B Ríos A Martínez-Alarcón L | 2013 | Transplant Proc2013,45,10: | 1 |
| 9 | Villous ad-enoma in augmentation colocystoplasty asociated to infiltrating urotelial cancer in bladder remanent显示文摘 | Husillos Alonso A SubiráRíos D Molina Escudero R | | 0,,: | 1 |
| 10 | Glucotoxicity and lipotoxicity:factors in the pathogenesis and evolution of type 2 diabetes显示文摘 | Durruty P García de los Ríos M | 2001 | Rev Med Chil2001,129,: | 1 |
| 11 | Bilateral ectopicpregnancy显示文摘 | De Los Ríos JF Castaeda JD Miryam A | 2007 | J Minim Invasive Gynecol2007,14,4: | 1 |
| 12 | High rate of long-term survival for high-risk lymphoma patients t reated with hematopoietic stem cell transplantation as consolidation or salvage therapy显示文摘 | Espigado I Ríos E Marín-Niebla A | 2008 | Transplant Proc2008,40,9: | 1 |
| 13 | Effect of diamond shapes and associated thermal boundary resistance on the thermal conductivity of diamond-based composites显示文摘 | FLAQUER J RíOS A MARTIN-MEIZISO A NOGALES S | 2007 | Computational Materials Science2007,41,2: | 1 |
| 14 | Socio-personal profile of teenagers opposed to organ donation显示文摘 | Conesa C Ríos Zambudio A Ramírez P | 2004 | Nephrol Dial Transplant2004,19,5: | 1 |
| 15 | Mycoplasma pneumoniae induces host-dependent pulmonary inflammation and airway obstruction in mice显示文摘 | Fonseca-Aten M Ríos AM Mejías A | 2005 | Am J Respir Cell Mol Biol2005,32,3: | 1 |
| 16 | Evaluation of fungal endophytes for lignocellulolytic enzyme production and wood biodegradation显示文摘 | Rómulo Oses Sofía Valenzuela Juanita Freer | 2006 | International Biodeterioration & Biodegradation2006,57,: | 1 |
| 17 | Attitudes of resident doctors toward different types of organ donation in a spanish transplant hospital显示文摘 | Ríos A Conesa C Ramírez P | 2006 | Transplant Proc2006,38,3: | 1 |
| 18 | A new recirculating enzymatic membrane reactor for ester synthesis in ionic liquid/supercritical carbon dioxide biphasic systems显示文摘 | Herndndez FJ de los Ríos A P Gomez D | 2006 | Appl Catal B:Environ2006,67,: | 1 |
| 19 | Influence of key residues on the heterologous extracellular production of fungal ribonuclease U2 in the yeast Pichia pastoris显示文摘 | Alvarez-García E García-Ortega L De los Ríos V | 2009 | Protein Expression and Purification2009,65,2: | 1 |
| 20 | Psychological care:social and family support for patients awaiting a liver transplant显示文摘 | López-Navas A Ríos A Riquelme A | | 0,,03: | 1 |