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| 1 | Apoptosis of neoplasm cell lines induced byhepatic peptides extracted from sucking porcine hepatocytes显示文摘 | Kong XP Zou QY Li RB Zheng PL Yang LP Jin SW | 1999 | World Journal of Gastroenterology1999，5，5： | 11 |
| 2 | Hepatology International|HBV相关慢加急性肝衰竭合并细菌感染患者预后模型的建立和验证显示文摘细菌感染是HBV相关慢加急性肝衰竭(HBV-ACLF)最常见的并发症之一,可导致高病死率。然而,目前关于HBV-ACLF合并细菌感染患者的预后模型建立的研究未见报道。该研究旨在建立和验证一个能预测HBV-ACLF合并细菌感染患者30 d死亡风险的临床模型。研究者筛选2018年6月—2020年12月在华中科技大学同济医学院附属同济医院被诊断为HBV-ACLF的住院患者,共513例患者纳入前瞻性队列,其中224例合并细菌感染患者纳入建模队列。通过logistic回归分析筛选出独立预测因素并建立预测HBV-ACLF合并细菌感染患者30 d死亡风险列线图。同时回顾性筛选2016年1月—2018年5月在该院被诊断为HBV-ACLF的住院患者,共192例患者纳入验证队列,用于评估列线图的区分度、校准度和临床实用性。 | 张忠威 陈韬 宁琴 YANG ZY CHENG QY | 2022 | 临床肝胆病杂志2022，38，4： | 9 |
| 3 | Pulmonary infection control window in treatment of severe respiratory failure of chronic obstructive pulmonary diseases: a prospective, randomized controlled, multi-centred study显示文摘Background Early withdraw from invasive mechanical ventilation (MV) followed by noninvasive MV is a new strategy for changing modes of treatment. This study was conducted to estimate the feasibility and the efficacy of early extubation and sequential noninvasive MV commenced at beginning of pulmonary infection control window in patients with exacerbated hypercapnic respiratory failure caused by chronic obstructive pulmonary diseases (COPD). Methods A prospective, randomized controlled study was conducted in eleven teaching hospitals' respiratory or medical intensive care units in China. Ninety intubated COPD patients with severe hypercapnic respiratory failure triggered by pulmonary infection (pneumonia or purulent bronchitis) were involved in the study. When the pulmonary infection had been controlled by antibiotics and comprehensive therapy, the 'pulmonary infection control window (PIC window)' has been reached. Each case was randomly assigned to study group (extubation and noninvasive MV via facial mask immediately) or control group (invasive MV was received continuously after PIC window by using conventional weaning technique).Results Study group (n=47) and control group (n=43) had similar clinical characteristics initially and at the time of PIC window. Compared with control group, study group had shorter duration of invasive MV [(6.4±4.4) days vs (11.3±6.2) days, P=0.000], lower rate of ventilator associated pneumonia (VAP) (3/47 vs 12/43, P=0.014), fewer days in ICU [(12±8) days vs (16±11) days, P=0.047] and lower hospital mortality (1/47 vs 7/43, P=0.025).Conclusions In COPD patients requiring intubation and invasive MV for hypercapnic respiratory failure, which is exacerbated by pulmonary infection, early extubation followed by noninvasive MV initiated at the start of PIC window may decrease significantly the duration of invasive MV, the risk of VAP and hospital mortality. | Wang, C Zhan, QY Cao, ZX Wei, LQ Cheng, ZZ Liu, S Zhang, JL Chen, RC Luo, Q Niu, SF Zhu, L Wu, DW Fang, BM Wu, TH Wang, CZ Liu, YN | 2005 | Chinese Medical Journal2005，，19： | 6 |
| 4 | Diterpenoid Alkaloids from Aconitum Pendulum显示文摘A new diterpenoid 12 -epiacetyldehydrolucidusculline (1) and a new norditerpenoid alkaloid 2-hydroxydeoxyaconitine (2) were isolated from the roots of Aconitum pendulum, together with eight known alkaloids aconitine (3), deoxyaconitine (4), 3-acetylaconitine (5), 12-epiacetyldehydronapelline (6), dehydrolucidusculline (7), dehydronapelline (8), 12 -epidehydrnapelline (9), and noeline (10). The structures of the new alkaloids (1-2) were determined on the basis of spectral method. | Zhang, SM Tan, LQ Ou, QY | 1997 | Chinese Chemical Letters1997，8，11： | 5 |
| 5 | Black and green tea consumption and the risk of coronary artery disease, a meta-analysis显示文摘 | Wang ZM Zhou, B Wang, YS Gong, QY Wang, QM Yan, JJ Gao, W Wang, LS | 2011 | 南京医科大学学报(自然科学版)2011，31，4： | 5 |
| 6 | Numerical Simulation for Refraction-Diffraction of Waves in Water of Slowly Varying Current and Topography显示文摘A new numerical finite difference iteration method for refraction-diffraction of waves in waterof slowly varying current and topography is developed in this paper.And corresponding theoretical modelincluding the dissipation term is briefly described,together with some analysis and comparison ofcomputational results of the model with measurements in a hydraulic scale model(Berkhoff et al.,1982).An example of practical use of the method is given,showing that the present model is useful to engineeringpractice. | Hong, GW Feng, WB Xia, QY Pan, SH | 1997 | China Ocean Engineering1997，12，4： | 5 |
| 7 | Discovery of virus pathogen from soft-shelled turtle Trionyx sinesis显示文摘THE soft-shelled turtle Trionyx sinesis, because of its nutritional and medicinal values, | Zhang, QY Li, ZQ Jiang, YL Liang, SC Gui, JF | 1997 | Chinese Science Bulletin1997，42，6： | 3 |
| 8 | Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer显示文摘 | Zhang XM Miao XP Liang G Hao BT Wang YG Tan W Li Y Guo YL He FC Wei QY Lin DX | 2006 | 中国生物学文摘2006，20，4： | 2 |
| 9 | Differential sensitivity to chloride and sodium ions in seedlings of Glycine max and Glycine soja under NaCI stress 显示文摘 | Luo QY Yu BJ Liu YL | 2004 | J Plant Physiology2004，，： | 2 |
| 10 | Hemsleyasine, a New Norditerpenoid Alkaloid from the Roots of Aconitum Hemsleyanum Var.Circinatum显示文摘A new norditerpenoid alkaloid, hemsleyasine 1, has been isolated from the roots of Aconitum hemsleyanum var. circinatum W. T. Wang and its structure was established by spectral methods (1 H- and 13C-NMR. 1H COSY, COLOC and nOes). | Xu, QY Wang, FP Tan, TCM Che, CT | 1997 | Chinese Chemical Letters1997，8，2： | 2 |
| 11 | Bolus dose remifentanil and sufentanil blunting cardiovascular intubation responses in children:a randomized,double-blind comparison显示文摘 | Liao X Yang QY Xue FS | 2009 | Ear J Anaesthesiol2009，26，1： | 1 |
| 12 | Kinetics of appearance of four hemorphins from bovine hemoglobin peptic hydrolysates by HPLC coupled with photodiode array detection显示文摘 | Sannier F Plot JM | 1996 | Biochem Biophys Acta1996，1295，： | 1 |
| 13 | Differential expression of PTEN in normal adult rat brain and upregulation of PTEN and p - Akt in the ischemic cerebral cortex显示文摘 | Cai QY Chen XS Zhong SC | 2009 | Anat Rec2009，292，4： | 1 |
| 14 | Mutational analysis of the transforming growth factor beta receptor type I gene in primary non-small cell lung cancer显示文摘 | Zhang HT Fei QY Chen F | 2003 | Lung Cancer2003，40，3： | 1 |
| 15 | Trends in prevalence of HIV, syphilis, hepatitis C, hepatitis B and sexual risk behav- ior among men who have sex with ruen 显示文摘 | Ma XY Zhang QY He X | 2007 | J Acquit Immune Defic Syndr2007，45，5： | 1 |
| 16 | CT and MRI characteristics of ossification of the ligamentum flava in the thoracic spine显示文摘 | Xiong L Zeng QY Jinkins JR | 2001 | Eur Radiol2001，11，9： | 1 |
| 17 | Insertion of an extra amino acid is the main cause of the low affinity of penicillin-binding protein 2 in penicillin-resistant strains of Neisseria gonorrhoeae 显示文摘 | Brannigan JA Tirodimos IA Zhang QY | 1990 | Mol Microbiol1990，4，： | 1 |
| 18 | Discovery and application of the companion fungus related to sclerotial formation from hyphae of Grifola umbellata显示文摘 | Guo SX Wang QY Zhuang WY | 2002 | Acta Botanica Sinica2002，44，： | 1 |
| 19 | The protective effect of L-arginine on ischemia-reperfusion injury in rat skin flaps 显示文摘 | Cordeiro PG Mastorakos DP Hu QY | 1997 | Plast Reconstr Surg1997，100，5： | 1 |
| 20 | Elevated C-reactive protein levels are associated with endothelial dysfunction in chronic cocaine users 显示文摘 | Meng QY Lima JA Lai H | 2003 | lnt J Cardiol2003，88，23： | 1 |
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