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| 1 | High-intensity focused ultrasound ablation:An effective bridging therapy for hepatocellular carcinoma patients显示文摘AIM:To analyze whether high-intensity focused ultrasound(HIFU) ablation is an effective bridging therapy for patients with hepatocellular carcinoma(HCC).METHODS:From January 2007 to December 2010,49 consecutive HCC patients were listed for liver transplantation(UCSF criteria).The median waiting time for transplantation was 9.5 mo.Twenty-nine patients received transarterial chemoembolization(TACE) as a bringing therapy and 16 patients received no treatment before transplantation.Five patients received HIFU ablation as a bridging therapy.Another five patients with the same tumor staging(within the UCSF criteria) who received HIFU ablation but not on the transplant list were included for comparison.Patients were comparable in terms of Child-Pugh and model for end-stage liver disease scores,tumor size and number,and cause of cirrhosis.RESULTS:The HIFU group and TACE group showed no difference in terms of tumor size and tumor number.One patient in the HIFU group and no patient in the TACE group had gross ascites.The median hospital stay was 1 d(range,1-21 d) in the TACE group and two days(range,1-9 d) in the HIFU group(P < 0.000).No HIFU-related complication occurred.In the HIFU group,nine patients(90%) had complete response and one patient(10%) had partial response to the treatment.In the TACE group,only one patient(3%) had response to the treatment while 14 patients(48%) had stable disease and 14 patients(48%) had progressive disease(P = 0.00).Seven patients in the TACE group and no patient in the HIFU group dropped out from the transplant waiting list(P = 0.559).CONCLUSION:HIFU ablation is safe and effective in the treatment of HCC for patients with advanced cirrhosis.It may reduce the drop-out rate of liver transplant candidate. | Tan To Cheung Sheung Tat Fan See Ching Chan Kenneth SH Chok Ferdinand SK Chu Caroline R Jenkins Regina CL Lo James YY Fung Albert CY Chan William W Sharr Simon HY Tsang Wing Chiu Dai Ronnie TP Poon Chung Mau Lo | 2013 | World Journal of Gastroenterology2013，19，20： | 23 |
| 2 | High-intensity focused ultrasound ablation as a bridging therapy for hepatocellular carcinoma patients awaiting liver transplantation显示文摘The scarcity of liver grafts in Asia leads to a significant dropout of patients from liver transplant waiting lists, particularly patients with hepatocellular carcinoma and a low model for end-stage liver disease score. In order to reduce dropping out, different bridging therapies are employed. We report the use of high-intensity focused ultrasound ablation as a bridging therapy for a patient with hepatocellular carcinoma of stage two and an extremely low platelet count (20×10 9 /L). The ablation was successful. Blood tests showed that his liver function was similar before and after the treatment. No adhesion was encountered in the liver transplantation performed six months later. | Tan To Cheung Kenneth SH Chok Regina CL Lo William W Sharr See Ching Chan Ronnie TP Poon Sheung Tat Fan Chung Mau Lo | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，5： | 3 |
| 3 | Synthesis, Spectroscopic and Electrochemical Properties of Rare Earth Double - Deckers with Tetra(tert - butyl) - 2,3 -naphthalocyaninato Ligands 显示文摘 | J Jiang W Liu K- W Poon D Du D P Arnold DKPNg | 2000 | Euro J Inorg Chem2000，205，： | 1 |
| 4 | lnvestigation of nickel suppression and cytocompatibility of surface-treated nickel - titanium shape memory alloys by using plasma immersion ion implantation显示文摘 | Yeung K W Poon R W Liu X Y et a| | 2005 | JBiomed Mater Res A2005，72，13： | 1 |
| 5 | Comparison of infection rate with the use of antibiotic-impregnated vs standard extraventricular drain-age devices:a prospective,randomized controlled trial显示文摘 | Pople I Poon W Assaker R | | 0，，01： | 1 |
| 6 | Uterine artery Doppler at 11 +0 to 13 +6 weeks and 21 +0 to 24 +6 weeks in the prediction of preeclampsia显示文摘 | Plasencia W Maiz N Poon L | | 0，，02： | 1 |
| 7 | Randomized study of percutaneous endoscopic gastrostomy versus nasogastric tubesfor enteral feeding in head and neck cancer patients treated with (chemo) radiation显示文摘 | CorryJ Poon W Mcphee N | | 0，，： | 1 |
| 8 | Provision of continuous VCR functions in interactive broadcast VoD systems 显示文摘 | POON W F LOK T FENG J | 2005 | IEEE Transition Broadcasting2005，51，4： | 1 |
| 9 | Asset pricing in segmented capital markets: Preliminary evidence from China-domiciled companies 显示文摘 | Poon W P H Firth M Fung H | 1998 | Pacific-Basin Finance Journal1998，6，3： | 1 |
| 10 | Retrospective analysis of 5037patients with nasopharyngeal carcinoma treated during 19761985:overall survival and patterns of failure显示文摘 | Lee AW Poon YF Foo W | 1992 | lnt J Radiat Oncol Biol Phys1992，23，2： | 1 |
| 11 | Retrospective analysis of 5037 patients with nasopharyngeal carcinoma treated during 1976 - 1985:overall survival and patterns of failure 显示文摘 | Lee A W Poon Y F Foo W | 1992 | Int J Radial Oncol Biol Phys1992，23，： | 1 |
| 12 | Retrospective analysis of 5037 patients with nasopharyngeal carcinoma treated during 1976~1985:overall survival and patterns of failure显示文摘 | Lee AW Poon YF W | 1992 | Int J Radiat Oncol Biol Phys1992，23，： | 1 |
| 13 | Adaptive Batching Scheme for Multicast Video-on-demand Systems显示文摘 | POON W E LO K T FENG J | 2001 | IEEE Transactions on Broadcasting2001，47，1： | 1 |
| 14 | Cerebrovascular reactivity andvasospasm after subarachnoid hemorrhage:a pilot study显示文摘 | Wong GK Ng SC Poon W W | 2006 | Neurology2006，66，11： | 1 |
| 15 | Retrospective and analysis of 5037 patients with nasopharyngeaI carcinoma treated during 1976 - 1985 :overall survival and patterns of failure 显示文摘 | Lee AW Poon YF Foo W | 1992 | Int J Radiat OncoI Biol Phys1992，23，2： | 1 |
| 16 | Integrated model for lane-use and signal-phase designs显示文摘 | Lam W H K Poon A C K Mung G K S | 1997 | Journal of Transportation Engineering1997，123，2： | 1 |
| 17 | Tissue factor expression correlates with tumor angiogenesis and invasiveness in human hepatocellular carcinoma 显示文摘 | Poon R T Lau C P Ho J W Yu W C Fan S T Wong J | 2003 | Clin Cancer Res2003，9，： | 1 |
| 18 | Retrospective analysis of 5037 patients with nasopharyngeal carcinoma treated during 1976 -1985 :overall survival and patterns of failure显示文摘 | Lee AWM Poon YF Foo W | 1992 | Int J Radiat Oncol Biol Phys1992，23，： | 1 |
| 19 | Electrically reconfigurable sili con microring resonator-based filter with waveguide-coupled feedback显示文摘 | Zhou L Poon A W | 2007 | Optics Express2007，15，5： | 1 |
| 20 | On-site sorting of con- struction and demolition waste in Hong Kong显示文摘 | Poon C S Ann T W Ng L H | 2001 | Re- sources Conservation and Recycling2001，32，2： | 1 |
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