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| 1 | Survival after inflammatory bowel disease-associated colorectal cancer in the Colon Cancer Family Registry显示文摘AIM: To investigate the survival of individuals with colorectal cancer (CRC) with inflammatory bowel disease (IBD-associated CRC) compared to that of individuals without IBD diagnosed with CRC. METHODS: Epidemiologic, clinical, and follow-up data were obtained from the Colon Cancer Family Registry (Colon CFR). IBD-associated cases were identified from self-report of physician diagnosis. For a subset of participants, medical records were examined to confirm self-report of IBD. Cox proportional hazards regression was applied to estimate adjusted hazard ratios (aHR) and 95%CI of mortality, comparing IBD-associated to non-IBD-associated CRC, adjusted for age at CRC diagnosis, sex, Colon CFR phase, and number of prior endoscopies. Following imputation to complete CRC stage information, adjustment for CRC stage was examined. RESULTS: A total of 7202 CRC cases, including 250 cases of IBD-associated CRC, were analyzed. Over a twelve year follow-up period following CRC diagnosis, 2013 and 74 deaths occurred among non-IBD associated CRC and IBD-associated CRC patients, respectively. The difference in survival between IBD-associated and non-IBD CRC cases was not statistically significant (aHR = 1.08; 95%CI: 0.85-1.36). However, the assumption of proportional hazards necessary for valid inference from Cox regression was not met over the entire follow-up period, and we therefore limited analyses to within five years after CRC diagnosis when the assumption of proportional hazards was met. Over this period, there was evidence of worse prognosis for IBD-associated CRC (aHR = 1.36; 95%CI: 1.05-1.76). Results were similar when adjusted for CRC stage, or restricted to IBD confirmed in medical records. CONCLUSION: These results support the hypothesis that IBD-associated CRC has a worse prognosis than non-IBD-associated CRC. | Scott V Adams Dennis J Ahnen John A Baron Peter T Campbell Steven Gallinger William M Grady Loic LeMarchand Noralane M Lindor John D Potter Polly A Newcomb | 2013 | World Journal of Gastroenterology2013,19,21: | 2 |
| 2 | Effect of different cycli- ng-off criteria and positive end-expiratory pressure during pre- ssure support ventilation in patients with chronic obstructive p- ulmonary disease显示文摘 | Chiumello D Polli F Tallarini F | 2007 | Crit Care Med2007,35,11: | 1 |
| 3 | Geometric morphometrics : recent applications to the study of evolution and development显示文摘 | Lawing A M Polly P D | 2010 | Journal of Zoology2010,280,1: | 1 |
| 4 | An analysis of decision making and treatment in thoracolumbar metastases 显示文摘 | Polly DW Jr Chou D Sembrano JN | 2009 | Spine2009,34,22: | 1 |
| 5 | The role of leiomyomas in infertili- ty显示文摘 | Bulletti C De Ziegler D Polli V | 1999 | J Am Assoc Gynecol Laparosc1999,6,4: | 1 |
| 6 | Transforaminal lumbar interbody fusion:clinical and radiographic results and complications in 100 consecutive patients显示文摘 | Potter B K Freedman B A Verwiebe E G Hall J M Polly D W Jr Kuklo T R | 2005 | J Spinal Disord Tech2005,18,: | 1 |
| 7 | Response to environmental factors and competition: skull, mandible and tooth shapes in Polish water shrews ( Neomys, Sorieidae, Mammalia) 显示文摘 | Rychlik L Ramalhinho G Polly P D | 2006 | Journal Com- pilation2006,44,4: | 1 |
| 8 | The role of leiomyomas in infertility 显示文摘 | Bulletti C De Ziegler D Polli V | 1999 | J Am Assoc Gynecol Laparosc1999,6,4: | 1 |
| 9 | Characteristics of uteri contractility during menses in women with mild to moderate endometriosis显示文摘 | Bulletti C Deziegler D Polli V | 2002 | Fertil Steril2002,77,6: | 1 |
| 10 | An analysis of decision making and treatment in thoracolumbar metastases显示文摘 | Polly DW Jr Chou D Sembrano JN | 2009 | Spine(Phila pa 1976)2009,34,22: | 1 |
| 11 | Effect of different cycling-off criteria and positive end- expiratory pressure during pressure support ventilation in patients with chronic obstructive pulmonary disease显示文摘 | Chiumello D Polli F Tallarini F | 2007 | Crit Care Med2007,35,11: | 1 |
| 12 | Traction versus side-bending radiographs:is the proximal thoracic curve the stiffer curve in double thoracic curves?显示文摘 | Kirk K L Kuklo T R Polly D W Jr | 2003 | Am J Orthop2003,32,6: | 1 |
| 13 | Pedicle morphology in thoracic adolescent idiopathic scoliosis:is pedicle fixation an anatomically viable technique 显示文摘 | POLLY D W POqq'ER B K KUKLO T | 2003 | Spine2003,29,18: | 1 |
| 14 | Collision-induced fluorescence of Cs2 the 1 + X1 + 3 )-~u --* ~-~g system 显示文摘 | Polly R Gruber D Windholz L | 1996 | J Chem Phys Lett1996,249,34: | 1 |
| 15 | Uterine contractility during the menstrual cycle显示文摘 | Bulletti C Ziegler D Polli V | 2000 | Hum Reprod2000,15,1: | 1 |
| 16 | Uterine contractility during the mensual cycle显示文摘 | Bulletti C Ziegler D Polli V | 2000 | Hum Reprod2000,,: | 1 |
| 17 | Importance of roasted sulphide concentrates characterization in the hydrometallurgical extraction of zinc显示文摘 | BALARlNI J C POLLI L D 0 MIRANDA T L S CASTRO R M Z D SALUM A | 2008 | Minerals Engineering2008,21,1: | 1 |
| 18 | Analysis ofdecision making and treatment in thoracolumbar metas- tases显示文摘 | Polly DW Jr Chou D Sembrano JN | 2009 | Spine2009,34,22: | 1 |
| 19 | An analys is of decision making and treat mentinthoraco lumbar metastases显示文摘 | Polly DW Jr Chou D Sembrano JN | 2009 | Spine2009,34,221: | 1 |
| 20 | Characteristics of uterine contractility during menses in women with mild to moderate endometriosis显示文摘 | Bulletti C De Zieqler D Polli V | 2002 | Fertil and Steril2002,77,6: | 1 |