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| 1 | Hypoxia-regulated microRNAs in human cancer显示文摘 | Guomin SHEN Xiaobo LI Yong-feng JIA Gary A PIAZZA Yaguang XI | 2013 | Acta Pharmacologica Sinica2013，34，3： | 18 |
| 2 | The interaction between the Wnt/β-catenin signaling cascade and PKG activation in cancer显示文摘The activation of the Wnt/β-catenin signaling cascade has been well studied and documented in colorectal cancer(CRC).The long-term use of non-steroidal anti-inflammatory drugs(NSAIDs) has been shown to reduce the incidence and risk of death from CRC in numerous epidemiological studies.The NSA1 D sulindac has also been reported to cause regression of precancerous adenomas in individuals with familial adenomatous polyposis who are at high risk of developing CRC.The mechanism responsible for cancer chemopreventive activity of NSAIDs is not well understood but may be unrelated to their cyclooxygenase inhibitory activity.Emerging evidence suggests that sulindac inhibits the growth of colon tumor cells by suppressing the activity of certain phosphodiesterase isozymes to activate cGMβ-dependent protein kinase,PKG,through the elevation of the second messenger cyclic guanosine monophosphote,cGMP.PKG activation has been shown to inhibit the nuclear translocation of β-catenin,reduce β-catenin mRNA and protein levels,and suppress the transcriptional activity of β-catenin.This review describes the relationship between the Wnt/β-catenin signaling cascade and the activation of PKG through PDE inhibition and elevation of intracellular cGMP levels. | Kevin Lee Gary A Piazza | 2017 | The Journal of Biomedical Research2017，31，3： | 7 |
| 3 | MicroRNAs are involved in the self-renewal and differentiation of cancer stem cells显示文摘MicroRNAs (miRNAs ) 是小非编码的 RNA 分子,其主要功能是在 post-transcriptional/translational 调整基因表示,铺平。MiRNAs 玩在正常生物过程的关键角色并且在人的疾病是通常调整 dys 的。干细胞被认为是 “ mother”包括身体的纸巾和机关的区分的房间的所有类型的房间。一个新奇假设建议肿瘤由从癌症干细胞导出的异构的房间组成,它有正常干细胞的类似于那些的自强和区别能力。癌症干细胞从各种各样的肿瘤被孤立并且描绘。在癌症干细胞的自强和区别支持 miRNAs 的关键规章的角色的给定的最近的研究,更好理解 miRNAs 的功能将提供无价的卓见进 tumorigenesis 和肿瘤前进的预防。在这评论,我们将在涉及癌症干细胞的自强和区别的 miRNAs 的学习总结研究进步。 | Zheng-ming WANG Wen-jun DU Gary A PIAZZA Yaguang XI | 2013 | Acta Pharmacologica Sinica2013，34，11： | 3 |
| 4 | Facial nerve paralysis in temporal bone fractures: outcomes after late decompression surgery 显示文摘 | Quaranta A Campobasso G Piazza F | 2001 | Acta Otolaryngol2001，121，5： | 1 |
| 5 | Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis显示文摘 | PIAZZA G A RAHM A L KRUTZSCH M | 1995 | Cancer Res1995，55，14： | 1 |
| 6 | Heart failure in patients with deep vein thrombosis显示文摘 | Piazza G Seddighzadeh A Goldhaber SZ | 2008 | Am J Cardiol2008，101，7： | 1 |
| 7 | Separation techniques for bile salts analysis显示文摘 | RODA A PIAZZA F BARALDINI M | 1998 | J Chromatogr B1998，717，12： | 1 |
| 8 | Association between platelet glycoprotein Ib-alpha and myocardial infarction : results of a pilot stud- y performed in male and female patients from Sicily 显示文摘 | Candore G Piazza G Crivello A | 2006 | Ann N Y Acad Sci2006，1089，： | 1 |
| 9 | ACE and AGTR1 poly- morphisms in elite rhythmic gymnastics 显示文摘 | Di Cagno A Sapere N Piazza M | 2013 | Genet Test Mol Biomark- ers2013，17，2： | 1 |
| 10 | End=to-end versus end-to-side venous mieroanastomoses in head and neck re- construction 显示文摘 | Piazza C Taglietti V Paderuo A | 2014 | Eur Arch Otorhinolaryngol2014，271，1： | 1 |
| 11 | Diamond Film Synthesis at Low Temperature显示文摘 | Piazza F Gonzalez J A Velazquez R | 2006 | Diamond and Related Materials2006，15，： | 1 |
| 12 | A rapid and sensitive 384-microtiter wells format chemiluminescent enzyme immunoassay for clenbuterol显示文摘 | Roda A Manetta A C Piazza F | 2000 | Talanta2000，52，2： | 1 |
| 13 | Chronic obstructive pulmonary disease and deep vein thrombosis: a prevalent combi nation显示文摘 | Shetty R Seddighzadeh A Piazza G | 2008 | J Thromb Thrombolysis2008，26，1： | 1 |
| 14 | Apoptosis primarily accounts for the growth inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction显示文摘 | PIAZZA G A RAHM A K FINN T S | 1997 | Cancer Res1997，57，12： | 1 |
| 15 | Chronic obstructive pul- monary disease and deep vein thrombosis:a prevalent combination显示文摘 | Shetty R Seddighzadeh A Piazza G | 2008 | J Thromb Thrombolysis2008，26，1： | 1 |
| 16 | What is the best test to predict outcome after prolonged cardiac arrest 显示文摘 | Sandroni C Barelli A Piazza O | 1995 | Eur Emcrg Med1995，2，1： | 1 |
| 17 | End-to-end versus end-to-side venous microanastomoses in head and neck reconstruction 显示文摘 | Piazza C Taglietti V Paderno A | 2014 | Eur Arch Otorhinolaryngol2014，271，1： | 1 |
| 18 | Laparoscopic biliopancreatic diversion: our preliminary experience with 201 consecutive cases显示文摘 | Piazza L Pulvirenti A Ferrara F | 2009 | Chirurgia Italiana2009，61，2： | 1 |
| 19 | Deep-vein thr- ombosis in the elderly显示文摘 | Piazza G Seddighzadeh A Goldhaber S Z | 2008 | Clin Appl Thromb Hemost2008，14，4： | 1 |
| 20 | Separation techniques for bile salts analysis 显示文摘 | Roda A Piazza F Baraldini M | 1998 | J Chromatogr B Biomed Sci Appl1998，717，12： | 1 |
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