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| 1 | Protective effect of electroacupuncture and moxibustion on gastric mucosal damage and its relation with nitric oxide in rats显示文摘INTRODUCTION Gastric mucosal injury is one of the common disorders,there are many reports subjicted to its pathogenesis treatment and prevention.We investigated the protective effect | Pei WF Xu GS Sun Y Zhu SL Zhang DQ | 2000 | World Journal of Gastroenterology2000，6，3： | 8 |
| 2 | Rhubarb extract partially improves mucosal integrity in chemotherapy-induced intestinal mucositis显示文摘AIM To investigate the effects of orally gavaged aqueous rhubarb extract(RE) on 5-fluorouracil(5-FU)-induced intestinal mucositis in rats. METHODS Female Dark Agouti rats(n = 8/group) were gavaged daily(1 mL) with water, high-dose RE(HDR; 200 mg/kg) or low-dose RE(LDR; 20mg/kg) for eight days. Intestinal mucositis was induced(day 5) with 5-FU(150 mg/kg) via intraperitoneal injection. Intestinal tissue samples were collected for myeloperoxidase(MPO) activity and histological examination. Xenopus oocytes expressing aquaporin 4 water channels were prepared to examine the effect of aqueous RE on cell volume, indicating a potential mechanism responsible for modulating net fluid absorption and secretion in the gastrointestinal tract. Statistical significance was assumed at P < 0.05 by one-way ANOVA. RESULTS B o d y w e i g h t w a s s i g n i f i c a n t l y r e d u c e d i n r a t s administered 5-FU compared to healthy controls(P < 0.01). Rats administered 5-FU significantly increased intestinal MPO levels(≥ 307%; P < 0.001), compared to healthy controls. However, LDR attenuated this effect in 5-FU treated rats, significantly decreasing ileal MPO activity(by 45%; P < 0.05), as compared to 5-FU controls. 5-FU significantly reduced intestinal mucosal thickness(by ≥ 29% P < 0.001) as compared to healthy controls. LDR significantly increased ileal mucosal thickness in 5-FU treated rats(19%; P < 0.05) relative to 5-FU controls. In xenopus oocytes expressing AQP4 water channels, RE selectively blocked water influx into the cell, induced by a decrease in external osmotic pressure. As water efflux was unaltered by the presence of extracellular RE, the directional flow of water across the epithelial barrier, in the presence of extracellular RE, indicated that RE may alleviate water loss across the epithelial barrier and promote intestinal health in chemotherapy-induced intestinal mucositis.CONCLUSION In summary, low dose RE improves selected parameters of mucosal integrity and reduces ileal inflammation, manifesting from 5-FU-induced intestinal mucositis. | Juliana E Bajic Georgina L Eden Lorrinne S Lampton Ker Y Cheah Kerry A Lymn Jinxin V Pei Andrea J Yool Gordon S Howarth | 2016 | World Journal of Gastroenterology2016，22，37： | 3 |
| 3 | The valence change from RE3+ (RE=Eu,Sm,Yb) in SrB4O7:RE prepared in air and the spectral properties of RE2+显示文摘 | PEI Z W SU Q ZHANG J Y | 1993 | Journal of Alloys and Compound1993，198，： | 2 |
| 4 | Efficient blue polymer light-emitting diodes from a series of soluble poly (paraphenylene)s显示文摘 | Yang Y Pei Q Heeger A J | 1996 | J Appl Phys1996，79，： | 2 |
| 5 | Determining burn degree of fire-damaged concrete constructions by thermoluminescence显示文摘NOWADAYS there are many skyscrapers in cities. If fire-damaged, the only way to lessen | Pei, JX Han, Y Sun, XH | 1997 | Chinese Science Bulletin1997，42，21： | 2 |
| 6 | The evolution of microstructure in a laser clad TiB-Ti composite coating 显示文摘 | KOOI B J PEI Y T DE HOSSON J Th M | 2003 | Acta Mater2003，51，2： | 2 |
| 7 | Granulocyte,granulocyte macrophage and macrophage colony stimulating factors can stimulate the invasive capacity of human lung cancer cells显示文摘 | Nakanishi Y Takayama K | 1999 | Br J Cancer1999，79，1： | 1 |
| 8 | Genome-wide analysis of the auxin response factors (ARF) gene family in rice ( Oryza sativa) 显示文摘 | Wang D Pei K Fu Y | 2007 | Gene2007，39，： | 1 |
| 9 | Polymer-enhance diffraction in an azo-dye-doped li-quid crystal显示文摘 | Pei M L Wang Y J Carlisle O O | 2001 | Society of Photo-Optical Instrumentation Engineers2001，40，8： | 1 |
| 10 | Convergence of Electric Bands for High Performance Bulk Thermoelectrics 显示文摘 | Pei Y Shi X LaLonde A | 2011 | Nature2011，473，7345： | 1 |
| 11 | Somatic PKD2 mutations in individual kidney and liver cysts support a 'two-hit'model for cystogenesis in type 2 autosomal polycystic kidney disease显示文摘 | Pei Y Watnick T He N | 1999 | J Am Soc Nephrol1999，10，： | 1 |
| 12 | Effective Wipe Detection in MPEG Compressed Video Using Macro Block Type Information 显示文摘 | Pei S C Chou Y Z | 2002 | IEEE Trans on Multimedia2002，4，3： | 1 |
| 13 | Protective effects of hydrogen gas on murine polymicrobial sepsis via reducing oxidative stress and HMGB1 release显示文摘 | Xie K Yu Y Pei Y | 2010 | Shock2010，34，1： | 1 |
| 14 | Efficient skyline and Top-k retrieval in subspaces 显示文摘 | TAO Y XIAO X PEI J | 2007 | IEEE Transactions on Knowledge and Data Engi- neering2007，19，8： | 1 |
| 15 | On OH density of an atmospheric pressure plasma jet by laser-induced fluorescence显示文摘 | Pei X Wu S Xian Y | 2014 | IEEE Transactions on Plasma Science2014，42，5： | 1 |
| 16 | Magnetic and electric bulge-test instrument for the determina- tion of coupling mechanical properties of functional free-standing films and flexible electronics显示文摘 | Yu Z Mao W Li F Feng X Pei Y Fang D | 2014 | Review of Scientific Instrument s2014，85，06： | 1 |
| 17 | Effects of straw mulching on soil temperature,evaporation and yield of winter wheat:field experiments on the North China Plain显示文摘 | CHEN S Y ZHANG X Y PEI D | 2007 | Annals of Applied Biology2007，150，3： | 1 |
| 18 | κ-opioid receptor mediates cardioprotection of ischemic preconditioning role of PKC and KATP显示文摘 | WANG G Y W U S PEI J M | 2001 | Am J Physiol2001，280，： | 1 |
| 19 | Preparation of silicon carbide nanotubes by hydrothermal method显示文摘 | Pei L Z Tang Y H Chen Y W | 2006 | J Appl Phys2006，99，11： | 1 |
| 20 | Long-range entangled carbon nanotube networks in polycarbonate显示文摘 | Singh S Pei Y Q Miller R | 2003 | Advanced Functional Materials2003，13，11： | 1 |
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