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60篇 您的检索式:作者名="Pappano"
    题名 作者 年代 出处 被引量
1L型钙流和反向钠—钙交换在豚鼠心室肌细胞兴奋—收缩偶联中的作用显示文摘目的 :比较和探讨L型钙流 [ICa(L) ]和反向钠—钙交换 (NCX)在触发豚鼠心室肌细胞兴奋—收缩偶联中的作用。方法 :以分离的豚鼠单个心室肌细胞为对象 ,采用膜片钳和单细胞收缩测量技术 ,给予 35℃的各种含药物细胞外液快速灌流 ,同时记录ICa(L) 和细胞收缩。结果 :①在 +10mV的钳制电压 ,使用硝苯地平 (Nif) 10~ 10 0 μmol/L和Nif 30 μmol/L +Cd2 +30 μmol/L ,阻滞ICa(L) 越多 ,细胞收缩被阻滞得越多 ,呈线性相关。②在 +5 0mV的钳制电压 ,Nif 10 0 μmol/L以及Nif 30 μmol/L +Cd2 +3 0 μmol/L仅能抑制部分细胞收缩 ,但剩余的细胞收缩起始时间明显延迟 ,且能被 5mmol/LNi2 +所阻滞。③在 +10 0mV的钳制电压 ,细胞收缩起始时间较 +5 0mV明显延迟 ,且不能被Nif 10 0 μmol/L和Nif 30 μmol/L +Cd2 +30 μmol/L所阻滞。结论 :在生理条件下 ,ICa(L) 是触发心室肌细胞兴奋—收缩偶联的主要途径 ,但在膜电位 >+5 0mV时 ,反向NCX也参与兴奋—收缩偶联。蒋彬 周希平 Achilles J. Pappano 2003中国应用生理学杂志2003,19,2:2
2Activa- tion of latent myostatin by the BMP-1/tolloid family of me- talloproteinases显示文摘Wolfman NW McPherron AC Pappano WN 2003PNAS2003,100,15:1
3Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases显示文摘Wolfman NM Mcpherron AC Pappano WN 2003Proc Natl Acad Sci USA2003,100,15:1
4Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases 显示文摘Wolfman NM McPherron AC Pappano WN 2003Proc Natl Acad Sci U S A2003,100,15:1
5Acti- vation of latent myostatin by the BMP - 1/tolloid family of metallo - proteinases 显示文摘WOLFMAN N W McPHERRON A C PAPPANO W N 2003Proc Natl Acad Sci USA2003,100,15:1
6Antimicrobial activity and synergism of some substituted flavonoids显示文摘ALVAREZ M A DEBALTISTA N B PAPPANO N B 2008Folia Microbiol2008,53,1:1
7The parasympathetic neuroeffect on the junction of the heart显示文摘Loffelholz K Pappano AJ 1985Pharmacol Res1985,37,:1
8The Year of the MOOC显示文摘Pappano L 2012The New York Times2012,2,12:1
9Elevated cAMP suppresses muscarinic inhibition of L-type calcium current in guinea-pig ventricular myocytes 显示文摘Sakai R Shen JB Pappano AJ 1999J Cardiovasc Pharmacol1999,34,:1
10Nicotine-induced restoration of action potentials to cardiac tissue depolarization by potassium 显示文摘Pappano AJ Rembish RA 1970Life Sci1970,9,24:1
11Bacteriostatic ac- tion of synthetic po|yhydroxylated ehalcones against Escherichia coli显示文摘Alvarez M L Zarelli V E Pappano N B 2004Bioeell2004,28,1:1
12Rotavirus显示文摘Bass ES Pappano DA Humiston SG 2007Pediatr Rev2007,28,5:1
13New directions for non-fuel uses of anthracites 显示文摘John M Andre' sen Caroline E Burgess Peter J Pappano 2004Fuel Processing Technology2004,85,12:1
14Mammalian BMP-1/Tolloid- related metalloproteinases, including novel family member mammalian Tolloid - like 2, have differential enzymatic activities and distributions of expression relevant to patteming and skeletogenesis显示文摘Scott IC Blitz IL Pappano WN 1999Dev Biol1999,213,2:1
15Effects of dimethylformamide and L-menthol permeation enhancers on transdermal delivery of quercetin 显示文摘OLIVELLA MS PAPPANO NB DEBATTISTA NB 2007Pharm Dev Technol2007,12,5:1
16Rotavirus 显示文摘Bass ES Pappano DA Humiston SG 2007Pediatr Rev2007,28,5:1
17Bone morpho-genetic protein- 1 processes probiglycan显示文摘Scott IC Imamura Y Pappano WN 2000J Biol Chem2000,275,30:1
18Prophylaxis against fluoreseeininduced anaphylactoid reactions显示文摘Rohr AS Pappano JE Jr 1992J Allergy Clin Immunol1992,90,9:1
19Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases显示文摘Wolfman N M McPherron A C Pappano W N 2003Proc Natl Acad Sei USA2003,100,15:1
20Bone morphogenetic protein- 1 processes probiglycan显示文摘Scott IC Imamura Y Pappano WN 2000J Biol Chem2000,275,30:1
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