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| 1 | Management of borderline and locally advanced pancreatic cancer:Where do we stand?显示文摘Many patients with pancreas cancer present with locally advanced pancreatic cancer(LAPC).The principle tools used for diagnosis and staging of LAPC include endoscopic ultrasound,axial imaging with computed tomography and magnetic resonance imaging,and diagnostic laparoscopy.The definition of resectability has historically been vague,as there is considerable debate and controversy as to the definition of LAPC.For the patient with LAPC,there is some level of involvement of the surrounding vascular structures,which include the superior mesenteric artery,celiac axis,hepatic artery,superior mesenteric vein,or portal vein.When feasible,most surgeons would recommend possible surgical resection for patients with borderline LAPC,with the goal of an R0 resection.For initially unresectable LAPC,neoadjuvant should be strongly considered.Specifically,these patients should be offered neoadjuvant therapy,and the tumor should be assessed for possible response and eventual resection.The efficacy of neoadjuvant therapy with this approach as a bridge to potential curative resection is broad,ranging from 3%-79%.The different modalities of neoadjuvant therapy include sin-gle or multi-agent chemotherapy combined with radiation,chemotherapy alone,and chemotherapy followed by chemotherapy with radiation.This review focuses on patients with LAPC and addresses recent advances and controversies in the field. | Jin He Andrew J Page Matthew Weiss Christopher L Wolfgang Joseph M Herman Timothy M Pawlik | 2014 | World Journal of Gastroenterology2014，20，9： | 11 |
| 2 | 人血浆硫氧化还原蛋白80随着年龄增长而增加,并在载脂蛋白E基因敲除小鼠中诱导炎症、血管生成和动脉粥样硬化显示文摘硫氧化还原蛋白(thioredoxin,TRX)1是一种普遍存在的12kD的蛋白质,可产生抗氧化和抗炎作用。由巨噬细胞产生的截断形式称为TRX80,其可诱导促炎细胞因子的上调。TRX80还促进小鼠腹膜和人巨噬细胞向促炎M1表型的分化。方法:使用特异性酶联免疫吸附试验测定血浆TRX1和TRX80水平。 | 刘莉 叶鹏 Couchie D Vaisman B Abderrazak A Mahmood DFD Hamza MM Canesi F Diderot V El Hadri K Nègre-Salvayre AE Le Page A Fulop T Remaley AT Rouis M | 2017 | 中华高血压杂志2017，25，6： | 9 |
| 3 | The anaphase-promoting complex:New subunits and regulation 显示文摘 | Page A M Hieter P | 1999 | Annu Rev Biochem1999，68，： | 2 |
| 4 | Elevated phosphorylation of AKT and Stat3 in protate,breast,and cervical cancer cells显示文摘 | Page C Huang M Jin X | 2000 | Int J Oncol2000，17，1： | 1 |
| 5 | Extracellular signal-regulated kinase(ERK) controls immediate early gene induction on corticostriatal stimulation显示文摘 | SGAMBATO V PAGES C ROGARD M | 1998 | JNeurosci1998，18，21： | 1 |
| 6 | Serum concentrations of insulin-like growth factor-1,soluble tumor necrosis factor receptor-1 and angiogenin in endometriosis patients显示文摘 | Steff AM Gagne D Page M | 2004 | Am J Reprod Immunol2004，51，2： | 1 |
| 7 | Corrosion inhibitor systems for remedial treatment of reinforced concrete( I): Calcium nitrite 显示文摘 | Ngala V T Page C L Page M M | 2002 | Corrosion Science2002，44，9： | 1 |
| 8 | Temporal trends in revascu- larization and outcomes after acute myocardial infarction among the very elderly显示文摘 | Page M Doucet M Eisenberg MJ | 2010 | CMAJ2010，182，13： | 1 |
| 9 | Wnt signaling in- duces gene expression of factors associated with bone destruction in lung and breast cancer显示文摘 | Johnson R W Merkel A R Page J M | 2014 | Clin Exp Metastasis2014，31，8： | 1 |
| 10 | An improved mouse model for endometriosis allows noninvasive assessment of lesion implantation and development 显示文摘 | Fortin M Lepine M Page M | 2003 | Fertil Steril2003，80，2： | 1 |
| 11 | Chloramphenicol and expression of multidrug efflux pump in Enterobacter aerogenes显示文摘 | Ghisalberti D Masi M Pages JM | 2005 | Biochem Biophys Res Commun2005，328，4： | 1 |
| 12 | Constitutively active Stat 3 oncogene product in human ovarian carcinoma cells显示文摘 | Huang M Page C Reynolds RK | 2000 | Gynecol Oncol2000，79，1： | 1 |
| 13 | A new fluorimetric assay for cytotoxity measurements in vitro 显示文摘 | Pag B Page M Noe I C | 1993 | International Journal of Oncology1993，3，： | 1 |
| 14 | Differential effects of lipopolysaccharide and tumor necrosis factor on monocytic IκB kinase signalsome activation and IκB proteolysis显示文摘 | Fischer C Page S Weber M | | 0，，： | 1 |
| 15 | Microstructural evolution in pulse plated nickel electrodeposits显示文摘 | El-Sherik M Erb U Page J | 1997 | Surf Coat Technol1997，88，13： | 1 |
| 16 | Angiogenic/lymphangiogenic factors and adaptation to extreme altitudes during an expedition to Mount Everest显示文摘 | Patitucci M Lugrin D Pages G | 2009 | Acta Physiologica2009，196，2： | 1 |
| 17 | Thermal behavior of amylose-lipid complex显示文摘 | | 1985 | Carbohydr Polym1985，5，： | 1 |
| 18 | Antigenic heterogeneity of vascular endothelium显示文摘 | Rose M Yacoub M | 1992 | Am J Pathol1992，141，： | 1 |
| 19 | Full scale moving bed biofilm reactor results from refinery and slaughter house treatment facilities显示文摘 | M W Page L Blaha | 2000 | Wat Sci & Tch2000，41，45： | 1 |
| 20 | Hormonal mechanism of dormancy induction in developing seeds显示文摘 | Le Page Degivry M T | 1998 | J Crop Production1998，1，1： | 1 |
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