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220篇 您的检索式:作者名="PRASAD G V"
    题名 作者 年代 出处 被引量
1Spontaneous transformation of human adult non-tumorigenic stem cells to cancer stem cells is driven by genomic instability in a human model of glioblastoma显示文摘Shims A Chettiar S Shepal V Rajendran G Prasad R Shastry P 2007中国神经肿瘤杂志2007,5,1:16
2Metabolic syndrome and chronic kidney disease:Current status and future directions显示文摘Metabolic syndrome(Met S) is a term used to denote a combination of selected,widely prevalent cardiovascular disease(CVD)-related risk factors.Despite the ambiguous definition of Met S,it has been clearly associated with chronic kidney disease markers including reduced glomerular filtration rate,proteinuria and/or microalbuminuria,and histopathological markers such as tubular atrophy and interstitial fibrosis.However,the etiological role of Met S in chronic kidney disease(CKD) is less clear.The relationship between MetS and CKD is complex and bidirectional,and so is best understood when CKD is viewed as a common progressive illness along the course of which MetS,another common disease,may intervene and contribute.Possible mechanisms of renal injury include insulin resistance and oxidative stress,increased proinflammatory cytokine production,increased connective tissue growth and profibrotic factor production,increased microvascular injury,and renal ischemia.MetS also portends a higher CVD risk at all stages of CKD from early renal insufficiency to end-stage renal disease.Clinical interventions for MetS in the presence of CKD should include a combination of weight reduction,appropriate dietary modification and increase physical activity,plus targeting of individual CVD-related risk factors such as dysglycemia,hypertension,and dyslipidemia while conforming to relevant national societal guidelines.G V Ramesh Prasad 2014World Journal of Nephrology2014,3,4:8
3New-onset diabetes mellitus after kidney transplantation:Current status and future directions显示文摘A diagnosis of new-onset diabetes after transplantation(NODAT) carries with it a threat to the renal allograft,as well as the same short-and long-term implications of type 2 diabetes seen in the general population.NODAT usually occurs early after transplantation,and is usually diagnosed according to general population guidelines.Non-modifiable risk factors for NODAT include advancing age,African American,Hispanic,or South Asian ethnicity,genetic background,a positive family history for diabetes mellitus,polycystic kidney disease,and previously diagnosed glucose intolerance.Modifiable risk factors for NODAT include obesity and the metabolic syndrome,hepatitis C virus and cytomegalovirus infection,corticosteroids,calcineurin inhibitor drugs(especially tacrolimus),and sirolimus.NODAT affects graft and patient survival,and increases the incidence of post-transplant cardiovascular disease.The incidence and impact of NODAT can be minimized through pre-and post-transplant screening to identify patients at higher risk,including by oral glucose tolerance tests,as well as multi-disciplinary care,lifestyle modification,and the use of modified immunosuppressive regimens coupled with glucose-lowering therapies including oral hypoglycemic agents and insulin.Since NODAT is a major cause of post-transplant morbidity and mortality,measures to reduce its incidence and impact have the potential to greatly improve overall transplant success.Sneha Palepu G V Ramesh Prasad 2015World Journal of Diabetes2015,6,3:8
4Post-transplant dyslipidemia: Mechanisms, diagnosis and management显示文摘Post-transplant dyslipidemia is highly prevalent and presents unique management challenges to the clinician. The two major outcomes to considerwith post-transplant therapies for dyslipidemia are preserving or improving allograft function, and reducing cardiovascular risk. Although there are other cardiovascular risk factors such as graft dysfunction, hypertension, and diabetes, attention to dyslipidemia is warranted because interventions for dyslipidemia have an impact on reducing cardiac events in clinical trials specific to the transplant population. Dyslipidemia is not synonymous with hyperlipidemia. Numerous mechanisms exist for the occurrence of posttransplant dyslipidemia, including those mediated by immunosuppressive drug therapy. Statin therapy has received the most attention in all solid organ transplant recipient populations, although the effect of proper dietary advice and adjuvant pharmacological and nonpharmacological agents should not be dismissed. At all stages of treatment appropriate monitoring strategies for side effects should be implemented so that the benefits from these therapies can be achieved. Clinicians have a choice when there is a conflict between various transplant society and lipid society guidelines for therapy and targets.Arnav Agarwal G V Ramesh Prasad 2016World Journal of Transplantation2016,6,1:6
5临床表现罕见的流行性角结膜炎1例:腺病毒角结膜上皮炎(英文)显示文摘腺病毒角结膜炎,由腺病毒血清型8,19,37引起。腺病毒结膜炎典型的体征包括耳前淋巴结病变,结膜充血水肿,结膜下出血,结膜滤泡。腺病毒角结膜炎角膜受累情况各不相同,多数患者有弥散的轻微的浅层角膜炎,局部隆起的点状上皮损害,随后形成上皮下混浊。我们报道一例罕见的腺病毒角结膜上皮炎,为临床表现特殊的流行性角结膜炎(EKC),并回顾相关特殊病例文献。患者,男,35岁,患腺病毒结膜炎,临床表现罕见,表现为角结膜上皮炎形式,这种病例文献未见报道。经过保守治疗患者痊愈。角结膜上皮炎可以是临床表现特殊的腺病毒角结膜炎。Sudesh Kumar Arya Badri Prasad Badhu Ritu Amatya V G Ramachandran Poonam Lavaju 2009国际眼科杂志2009,9,8:4
6Recent advances in new-onset diabetes mellitus after kidney transplantation显示文摘A common challenge in managing kidney transplant recipients(KTR)is posttransplant diabetes mellitus(PTDM)or diabetes mellitus(DM)newly diagnosed after transplantation,in addition to known pre-existing DM.PTDM is an important risk factor for post-transplant cardiovascular(CV)disease,which adversely affects patient survival and quality of life.CV disease in KTR may manifest as ischemic heart disease,heart failure,and/or left ventricular hypertrophy.Available therapies for PTDM include most agents currently used to treat type 2 diabetes.More recently,the use of sodium glucose co-transporter 2 inhibitors(SGLT2i),glucagon-like peptide-1 receptor agonists(GLP-1 RA),and dipeptidyl peptidase 4 inhibitors(DPP4i)has cautiously extended to KTR with PTDM,even though KTR are typically excluded from large general population clinical trials.Initial evidence from observational studies seems to indicate that SGLT2i,GLP-1 RA,and DPP4i may be safe and effective for glycemic control in KTR,but their benefit in reducing CV events in this otherwise high-risk population remains unproven.These newer drugs must still be used with care due to the increased propensity of KTR for intravascular volume depletion and acute kidney injury due to diarrhea and their single-kidney status,pre-existing burden of peripheral vascular disease,urinary tract infections due to immunosuppression and a surgically altered urinary tract,erythrocytosis from calcineurin inhibitors,and reduced kidney function from acute or chronic rejection.Tess Montada-Atin G V Ramesh Prasad 2021World Journal of Diabetes2021,12,5:2
7Micro- structural Modeling of Metadynamic Recrystallization in Hot Working of In718 Superalloy 显示文摘Medeiros S C Prasad Y V R K Frazier W G 2000Materials Science and Engineering2000,293,:1
8Micro- structural Modeling of Metadynamic Recrystallization in Hot Working of IN 718 Superalloy 显示文摘Medeiros S C Prasad Y V T K Frazier W G 2000Materials Science and Engi- neering2000,293,12:1
9Identification of keratins18,19 and heat-shock protein 90 beta as candidate substrates of proteolysis during ionizing radiation-induced apoptosis of estrogen-receptor negative breast tumor cells显示文摘PRASAD S SOLDATENKOV V A SRINIVASARAO G 1998Int J Oncol1998,13,4:1
10Work hardening model based on multiple dislocation densities显示文摘Prasad G V Goerdeler M Gottstein G 2005Materials Science and Engineering A2005,,:1
11Unstable flow during supratransus working of Ti-6Al-4V 显示文摘SESHACHARYULU T MEDEIROS S C FRAZIER W G PRASAD Y V R K 2001Materials Letters2001,47,:1
12A comparative study of tribological behavior of plasma and D-Gun sprayed coatings under different wear modes显示文摘G Sundararajan K U M Prasad D S Rao S V Joshi 1998Journal of Materials Engineering and Performance1998,7,3:1
13Influence of surface evaporation on stratification in different aspect ratios 显示文摘PRASANTH K S PRASAD B V S S S VENKATARATHNAM G 2007liquid hydrogen tanks of International Journal of Hydrogen Energy2007,32,12:1
14Effect of silica particles on the stability of methanehydrates 显示文摘Prasad P S R Chari V D Sharma D V S G K 2012Fluid Phase Equilibria2012,318,:1
15Friction and wear mecha- nisms in MoS:/Sb2OJAu nanocomposite coatings 显示文摘Scharf T W Kotula P G Prasad S V 2010Acta Materialia2010,58,:1
16A coupled piezoelectric-electromagnetic energy harvesting technique for achieving increased power output through damping matching显示文摘CHALLA V R PRASAD M G FISHER F T 2009Smart Materials&Structures2009,18,9:1
17A feature-based part description system for computer-aided process planning显示文摘JASTHI S R PRASAD A V S R K MANIDHAR G RAO P N RAO U R K TEWARI N K 1994Journal of Design and Manufacturing1994,4,1:1
18Pre- and Post- flowering photosynthetic contribution to grain yield in rice 显示文摘Venkateswarlu B G Prasad G S V 1980Indian J Plant Physiol1980,23,:1
19A vibration energy harvesting device with bidirectional resonance frequency tenability显示文摘CHALLA V R PRASAD M G SHI Y 2008Smart Materials and Structures2008,17,1:1
20Comprehensive analysis of normal and diabetic heart rate signals:A review显示文摘FAUST O PRASAD V R SWAPNA G CHATTOPADHYAY S LIM T-C 0,,05:1
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