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| 1 | Recent trends in liver transplantation for alcoholic liver disease in the United States显示文摘AIM To examine temporal changes in the indications for liver transplantation(LT) and characteristics of patients transplanted for alcoholic liver disease(ALD).METHODS We performed a retrospective cohort analysis of trends in the indication for LT using the United Network for Organ Sharing(UNOS) database between 2002 and 2015. Patients were grouped by etiology of the liver disease and characteristics were compared using χ~2 and t-tests. Time series analysis was used identifying any year with a significant change in the number of transplants per year for ALD, and before and after eras were modeled using a general linear model. Subgroup analysis of recipients with ALD was performed by age group, gender, UNOS region and etiology(alcoholic cirrhosis, alcoholic hepatitis and hepatitis C-alcoholic cirrhosis dual listing).RESULTS Of 74216 liver transplant recipients, ALD(n = 9400, 12.7%) was the third leading indication for transplant after hepatitis C and hepatocellular carcinoma. Transplants for ALD, increased from 12.8%(553) in 2002 to 16.5%(1020) in 2015. Time series analysis indicated a significant increase in the number of transplants per year for ALD in 2013(P = 0.03). There were a stable number of transplants per year between 2002 and 2012(linear coefficient 3, 95%CI:-4.6, 11.2) an increase of 177 per year between 2013 and 2015(95%CI: 119, 234). This increase was significant for all age groups except those 71-83 years old, was observed for both genders, and was incompletely explained by a decrease in transplants for hepatitis C and ALD dual listing. All UNOS regions except region 9 saw an increase in the mean number of transplants per year when comparing eras, and this increase was significant in regions 2, 3, 4, 5, 6, 8, 10 and 11.CONCLUSION There has been a dramatic increase in the number of transplants for ALD starting in 2013. | Catherine E Kling James D Perkins Robert L Carithers Dennis M Donovan Lena Sibulesky | 2017 | World Journal of Hepatology2017，9，36： | 6 |
| 2 | Studies of wax deposi tion in the Trans-Alaska Pipeline显示文摘 | Burger E D Perkins T K Striegler J H | 1981 | Journal of Petroleum Tech nology1981，33，6： | 1 |
| 3 | The validity of the imbert'ficklaw as applied to applanation tonometry 显示文摘 | Gloster J Perkins E S | 1963 | Experimental Eye Research1963，2，3： | 1 |
| 4 | Metastability in Near-surface Rocks of Minerals in the System Al2O3-SiO2-H2O显示文摘 | Anovitz L M Perkins D Essene E J | | 0，，39： | 1 |
| 5 | Environmental regu- lation and the cross-border diffusion of new technology : Evidence from automobile patents 显示文摘 | Dechezlepretre A Neumayer E Perkins R | 2008 | Research Policy2008，44，1： | 1 |
| 6 | Evolution and future directions of the ad hoe ondemand distance-vector routing protocol显示文摘 | Belding-Royer E M Perkins C E | 2003 | Ad Hoc Networks2003，1，： | 1 |
| 7 | Optimal grade transition and selection of closed-loop controllers in a gas-phase olefin polymerization fluidized bed reactor显示文摘 | CHATZIDOUKAS C PERKINS J D PISTIKOPOULOS E N | 2003 | Chemical Engineering Science2003，58，16： | 1 |
| 8 | Online travel reviews as persuasive communication:the effects of content type, source, and certification logos on con sumer behavior显示文摘 | SPARKS B A PERKINS H E BUCKLEY R | 2013 | Tourism Management2013，39，2： | 1 |
| 9 | Adverse outcome pathways for regulatory applications: examination of four case studies with different degrees of completeness and scientific confidence 显示文摘 | PERKINS E J ANTCZAK P BURGOON L | 2015 | Toxicol Sci2015，148，1： | 1 |
| 10 | The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway 显示文摘 | Perkins D Pereira E F Gober M | 2002 | J Virol2002，76，3： | 1 |
| 11 | Rhoptry organelles of apicomplexan parasites显示文摘 | Perkins M E | 1992 | Parasitol Today1992，8，1： | 1 |
| 12 | Long-time behavior and coexistence in a mutually catalytic branching model显示文摘 | Dawson D A Perkins E | 1998 | Ann Probab1998，26，3： | 1 |
| 13 | Surgical handling characterislics of anethylene vinyl alcohol copolymer compared with N-butyl cyanoacrylate used for embolization of vessels in an arteriove nous malformation resection model in swine显示文摘 | Akin E D Perkins E Ross I B | 2003 | Neurosury2003，98，2： | 1 |
| 14 | Detection of renal function decline in patients with diabetes and normal or elevated GFR by serial measurements of serum cystatin C concentration:results of a 4-year follow-up study显示文摘 | NELSON R G OSTRANDER B E | 2005 | J Am Soc Nephrol2005，16，5： | 1 |
| 15 | Studies of Wax Deposition in the Trans Alaska Pipeline 显示文摘 | Burger E D Perkins T K Striegler J H | 1981 | J Pe! Technol1981，33，6： | 1 |
| 16 | Alteration in myocardial 201T1 distribution in patients with chronic systemic hypertension undergoing single-photon emission computed tomography显示文摘 | Depuey EG Guertler-Krawczynska E Perkins JV | 1988 | Am J Cardiol1988，62，： | 1 |
| 17 | Highly dynamic destination-sequence distance-vector routing (DSDV) for mobile computers显示文摘 | PERKINS C E BHAGWAT P | 1994 | 24(4):234-2441994，24，4： | 1 |
| 18 | Mobile IP Joins Forces with AAA显示文摘 | Perkins C E | 2000 | IEEE Personal Communications2000，7，4： | 1 |
| 19 | Mobile IP显示文摘 | Perkins C E | 1997 | IEEE Communication Magazine1997，35，5： | 1 |
| 20 | Iliofemoral deep vein thrombosis: conventional therapy versus lysis and percuataneous transluminal angioplasty and stenting显示文摘 | ABURAHMA A F PERKINS S E WULU J J | 2001 | Ann Surg2001，233，6： | 1 |
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