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| 1 | Spinal cord injury in the setting of traumatic thoracolumbar fracture is not reliably associated with increased risk of associated intra-abdominal injury following blunt trauma:An analysis of a National Trauma Registry database显示文摘Purpose:There is a common opinion that spinal fractures usually reflect the substantial impact of injuries and therefore may be used as a marker of significant associated injuries,specifically for intra-abdominal injury(IAI).The impact of concomitant spinal cord injury(SCI)with the risk of associated IAI has not been well clarified.The aim of this study was to evaluate the incidence and severity of IAIs in patients suffering from spinal fractures with or without SCI.Methods:A retrospective cohort study using the Israeli National Trauma Registry was conducted.Patients with thoracic,lumbar and thoracolumbar fractures resulting from blunt mechanisms of injury from January 1,1997 to December 31,2018 were examined,comparing the incidence,severity and mortality of IAIs in patients with or without SCI.The collected variables included age,gender,mechanism of injury,incidence and severity of the concomitant IAIs and pelvic fractures,abbreviated injury scale,injury severity score,and mortality.Statistical analysis was performed using GraphPad InStat?Version 3.10,with Chi-square test for independence and two sided Fisher’s exact probability test.Results:Review of the Israeli National Trauma Database revealed a total of 16,878 patients with spinal fractures.Combined thoracic and lumbar fractures were observed in 1272 patients(7.5%),isolated thoracic fractures in 4967 patients(29.4%)and isolated lumbar fractures in 10,639 patients(63.0%).The incidence of concomitant SCI was found in 4.95%(63/1272),7.65%(380/4967)and 2.50%(266/10639)of these patients,respectively.The overall mortality was 2.5%,proving higher among isolated thoracic fracture patient than among isolated lumbar fracture counterparts(11.3%vs.4.6%,p<0.001).Isolated thoracic fractures with SCI were significantly more likely to die than non-SCI counterparts(8.2%vs.3.1%,p<0.001).There were no differences in the incidence of IAIs between patients with or without SCI following thoracolumbar fractures overall or in isolated thoracic fractures;although isolated lumbar fractures patients with SCI were more likely to have renal(3.4%vs.1.6%,p=0.02)or bowel injuries(2.3%vs.1.0%,p=0.04)than the non-SCI counterparts.Conclusion:SCI in the setting of thoracolumbar fracture does not appear to be a marker for associated IAI.However,in a subset of isolated lumbar fractures,SCI patient is associated with increased risks for renal and bowel injury. | Veacheslav Zilbermints Yehuda Hershkovitz Kobi Peleg Joseph J.Dubose Adi Givon David Aranovich Mickey Dudkiewicz Israeli Trauma Group Boris Kessel | 2021 | Chinese Journal of Traumatology2021,24,3: | 9 |
| 2 | Analysis of incidence of traumatic brain injury in blunt trauma patients with Glasgow Coma Scale of 12 or less显示文摘 | Alexander Becket Kobi Peleg Oded Olsha Adi Givon Boris Kessel Israeli Trauma Group | 2018 | Chinese Journal of Traumatology2018,21,3: | 7 |
| 3 | Acinetobacter baumannii Emergence of a Successful Pathogen显示文摘 | Peleg AY Seifert H Paterson DL | 2008 | Clin Microbiol Rev2008,21,3: | 4 |
| 4 | α1-antitrypsin increases interleukin-1 receptor antagonist production during pancreatic islet graft transplantation显示文摘尽管为有类型 1 糖尿病的个人的小岛移植被显示了产出优异的血葡萄糖控制,它为长期的控制仍然保持不适当。这是部分,由于小岛损害和压力,那能导致贝它房间损失。过量 IL-1β 的抑制;活动可能最小化小岛损害,因此保存工作。IL-1 受体对手(IL-1Ra ) , IL-1β 的一个内长的禁止者;,保护小岛免受导致 cytokine 的坏死和 apoptosis 的伤害。因此,在 IL-1β 之间的不平衡;并且 IL-1Ra 可能影响到小岛的 allogeneic 和自体免疫的回答的功课。我们的组以前证明传播丝氨酸朊酶禁止者人 alpha-1-antitrypsin (hAAT ) ,以及 immunomodulatory 活动。在现在的学习,我们寻求了决定是否胰腺的小岛 hAAT 的 allograft 保护的活动被 IL-1Ra 调停感应。我们的结果证明 hAAT 在刺激巨噬细胞在 IL-1Ra 表示导致了 2.04 褶层增加并且 hAAT-pre-treated 小岛接枝在 IL-1Ra 抄本层次展出了 4.851 褶层增加,它与中等煽动性的侧面被联系。出人意料地,从 IL-1Ra-knockout 鼠标被孤立并且在 grafting 前与 hAAT 预先对待进野类型的鼠标的小岛在大概从渗入主机房间被导出的 intragraft IL-1Ra 表示产出增加,当主机的 hAAT 处理不在时的虽然。确实, hAAT-pre-treated 小岛产生了能在有教养的巨噬细胞导致 IL-1Ra 生产的 hAAT 免费的调节媒介。最后,我们证明 hAAT 为 p65 支持了不同 phosphorylation 和原子 translocation 模式,为 IL-1Ra 要求的一个关键抄写因素表示。 | Avishag Abecassis Ronen Schuster Galit Shahaf Eyal Ozeri Ross Green David E Ochayon Peleg Rider Eli C Lewis | 2014 | Cellular & Molecular Immunology2014,11,4: | 2 |
| 5 | Acinetobacter baumannii bloodstream infection while receiving tigecyeline: a cautionary report显示文摘 | Peleg AY Potoski BA Rea R | 2007 | J Antimicrob Chemother2007,59,: | 1 |
| 6 | Improving resolution by image matching显示文摘 | Irani M Peleg S | 1991 | CVGIP : Graphical Models and Image Proc1991,53,3: | 1 |
| 7 | The clinical significance of sinus membrane perforation during augmentation of the maxillary sinus 显示文摘 | Ardekian L Oved - Peleg E Mactei E | 2006 | Oral Maxillofac Surg2006,64,2: | 1 |
| 8 | Estimation and classification of polynomialphase signals 显示文摘 | PELEG S PORAT B | 1991 | IEEE Transactions on Information Theory1991,37,2: | 1 |
| 9 | An optical submicrometer calcium sensor with conductance sensing capability显示文摘 | SHALOM S STRINKOVSKI A PELEG G | 1997 | AnalBiochem1997,244,2: | 1 |
| 10 | Frequency response of non - linear single degree of freedom systems显示文摘 | Peleg K | 1979 | International Jouranl of mechanical science1979,21,1: | 1 |
| 11 | Theoretical comparison of a new and the traditional method to calculate Clostridium botulinum survival during thermal inactivation显示文摘 | Campanella OS Peleg M | 2001 | Journal of Science of Food and Agriculture2001,81,2: | 1 |
| 12 | Linear FM Signal Parameter Estimation form Discrete Time Observations 显示文摘 | Peleg S Porat B | 1991 | IEEE Trans on Aerospace and Electronic systems1991,27,7: | 1 |
| 13 | Mosai?cing on adaptive manifolds显示文摘 | PELEG S ROUSSO B RAV-ACHA A | 2000 | IEEE Trans on Pattern Analysis and Machine Intelligence2000,22,10: | 1 |
| 14 | Medically important bacteri- al-fungal interactions 显示文摘 | Peleg AY Hogan DA Mylonakis E | 2010 | Nat Rev Microbiol2010,8,5: | 1 |
| 15 | Optimization of L-malic acid production by Aspergillus flavus in a stirred fementor显示文摘 | BATTAT E PELEG Y BERCOVITZ A | 1991 | Biotechnology and Bioengineering1991,37,: | 1 |
| 16 | Periodontal care may improve systemic inflammation显示文摘 | Blum A Front E Peleg A | 2007 | Clin Invest Ned2007,30,3: | 1 |
| 17 | Phenotypic detection of carbapenem-susceptible metallo beta lactamase producing gram-negative bacilli in the clinical laboratory 显示文摘 | Franklin C Liolios L Peleg AY | 2006 | J Clin Microbiol2006,44,9: | 1 |
| 18 | Improving resolution by image registration显示文摘 | Peleg S | 1991 | CVGIP:Graphical Models and Image Processing1991,53,3: | 1 |
| 19 | Acinetobacter baumannii:Emergence of a successful pathogen显示文摘 | Peleg AY Seifert H Paterson DL | 2008 | Clin Microbiol Rev2008,21,3: | 1 |
| 20 | A 20-epi-side chain restores growth-regulatory and transcriptional activities of an a ring-modified hybrid analogue of 1α,25-dihydroxyvitamin D3 without increasing its affinity to the vitamin D3 receptor显示文摘 | PELEG S LIU Y Y REDDY S | 1996 | J Cell Biochem1996,63,2: | 1 |