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| 1 | Preservation solutions used during abdominal transplantation:Current status and outcomes显示文摘Organ preservation remains an important contributing factor to graft and patient outcomes. During donor organ procurement and transportation, cellular injury is mitigated through the use of preservation solutions in conjunction with hypothermia. Various preservation solutions and protocols exist with widespread variability among transplant centers. In this review of abdominal organ preservation solutions, evolution of transplantation and graft preservation are discussed followed by classification of preservation solutions according to the composition of electrolytes, impermeants, buffers, antioxidants, and energy precursors. Lastly, pertinent clinical studies in the setting of hepatic, renal, pancreas, and intestinal transplantation are reviewed for patient and graft survival as well as financial considerations. In liver transplants there may be some benefit with the use of histidine-tryptophan-ketoglutarate(HTK) over University of Wisconsin solution in terms of biliary complications and potential cost savings. Renal grafts may experience increased initial graft dysfunction with the use of Euro-Collins thereby dissuading its use in support of HTK which can lead to substantial cost savings. University of Wisconsin solution and Celsior are favored in pancreas transplants given the concern for pancreatitis and graft thrombosis associated with HTK. No difference was observed with preservation solutions with respect to graft and patient survival in liver, renal, and pancreas transplants. Studies involving intestinal transplants are sparse but University of Wisconsin solution infused intraluminally in combination with an intra-vascular washout is a reasonable option until further evidence can be generated. Available literature can be used to ameliorate extensive variation across centers while potentially minimizing graft dysfunction and improving associated costs. | Nicholas Latchana Joshua R Peck Bryan A Whitson Mitchell L Henry Elmahdi A Elkhammas Sylvester M Black | 2015 | World Journal of Transplantation2015，5，4： | 5 |
| 2 | ^(99m)TC-Methylene diphosphonate uptake at injury site correlates with osteoblast differentiation and mineralization during bone healing in mice显示文摘99m Tc-Methylene diphosphonate(99m Tc-MDP) is widely used in clinical settings to detect bone abnormalities.However, the mechanism of99 m Tc-MDP uptake in bone is not well elucidated. In this study, we utilized a mouse tibia injury model, single-photon emission computed tomography(gamma scintigraphy or SPECT),ex vivo micro-computed tomography, and histology to monitor99 m Tc-MDP uptake in injury sites during skeletal healing. In an ex vivo culture system, calvarial cells were differentiated into osteoblasts with osteogenic medium, pulsed with99 m Tc-MDP at different time points, and quantitated for99 m Tc-MDP uptake with a gamma counter. We demonstrated that99 m Tc-MDP uptake in the injury sites corresponded to osteoblast generation in those sites throughout the healing process. The99 m Tc-MDP uptake within the injury sites peaked on day 7 post-injury, while the injury sites were occupied by mature osteoblasts also starting from day 7.99 m Tc-MDP uptake started to decrease 14 days post-surgery, when we observed the highest level of bony tissue in the injury sites. We also found that99 m Tc-MDP uptake was associated with osteoblast maturation and mineralization in vitro. This study provides direct and biological evidence for99 m Tc-MDP uptake in osteoblasts during bone healing in vivo and in vitro. | Zhendong A Zhong Anderson Peck Shihong Li Jeff Van Oss John Snider Casey J Droscha Tingtung A Chang Bart O Williams | 2015 | Bone Research2015，3，2： | 2 |
| 3 | Zinc nutrition influences the protein composition of flour in bread wheat ( Triticum aestivum L) 显示文摘 | Peck A W McDonald G K Graham R D | 2008 | J Cereal Sci2008，47，2： | 1 |
| 4 | Development of an aerodynamiclevitation technique to study coal particle combustion显示文摘 | Peck R E Pollock M A | 1981 | Fuel1981，60，8： | 1 |
| 5 | Molecular cloning, DNA sequence, and gene expression of the oxalyl - coenzyme A decar- boxylase gene, oxc, from the bacterium Oxalobaeter formigenes 显示文摘 | LUNG H Y BAETZ A L PECK A B | 1994 | JBaeteriol1994，176，8： | 1 |
| 6 | Persistent photopsia following course of oral voriconazole显示文摘 | Kadikoy H Barkmeier A Peck B | 2010 | J Ocul Pharmacol Ther2010，26，4： | 1 |
| 7 | The physiology of polar marine zooplankton显示文摘 | Clarke A Peck L S | 1991 | Polar Research1991，10，2： | 1 |
| 8 | Hole doping of the CuO2 chains(La,Sr,Ca)14Cu24 O41显示文摘 | CARTER S A BATLOGG B CAVA R J KRAJEWSKI J J PECK JR W F RICE T M | 1996 | Phys Rev Lett1996，77，7： | 1 |
| 9 | Continental climate response to orbital forcing from biogenic silica records in Lake Baikal 显示文摘 | Colman S M Peck J A Karabanov E B | 1995 | Nature1995，378，： | 1 |
| 10 | MicroRNA expression profiles classify human cancers显示文摘 | LU J Getz G Miska EA Alvarez-Saavedra E Lamb J Peck D Sweet-Cordero A Ebert BL Mak RH Ferrando AA | | 0，，： | 1 |
| 11 | A dose-controlled study of 153Sm-ehtylene diamine tetra methylene phosphonate(EDTMP)in the treatment of patients with painful bone metastases显示文摘 | Resche I chatal JF Pecking A | 1997 | Eur J Cancer1997，33，10： | 1 |
| 12 | A rock-magnetic recordfromLake Baikal, Siberia ; Evidence for Late Quaternary climatechange显示文摘 | Peck J A King J W Colman S M | 1994 | Earth and Planetary Science Letters1994，122，： | 1 |
| 13 | Breaking old paradigms : Th17 cells in autoim- mune arthritis 显示文摘 | Peck A Mellins ED | 2009 | Clin Immuno12009，132，3： | 1 |
| 14 | Comparative analysis of lymphoscin tigraphy between lipedema and lower limb lymphedema显示文摘 | Boursier V Pecking A Vignes S | 2004 | J Mal Vase2004，29，5： | 1 |
| 15 | Current evaluation of lymphedema and assessment by lymphoscintigraphy of the effect of a micronized flavonoid fraction in the treatment of upper limb lymphedema显示文摘 | Pecking A P Rambert P | 1994 | Phlebology1994，45，1： | 1 |
| 16 | Moisture profile development and air compression during water uptake by bounded porous dodies : 2: Horizontal col-umns 显示文摘 | PECK A J | 1965 | Soil Science1965，100，： | 1 |
| 17 | Signal transducer and activator of transcription-3 and breast cancer prognosis显示文摘 | SATO T NEILSON L M PECK A R | 2011 | Am J Cancer Res2011，1，： | 1 |
| 18 | A magnetic mineralrecord of Late Quaternary tropical climate variability fromLake Bosumtwi, Ghana 显示文摘 | Peck J A Green R R Shanahan T | 2004 | Palaeogeography Palaeoclimatolo-gy Palaeoecology2004，215，12： | 1 |
| 19 | Change of moisture tension with temperature and air pressure: Theoretical显示文摘 | Peck A J | 1960 | Soil Science1960，89，30： | 1 |
| 20 | The Social Regulation of Uneven Development:'Regulatory Deficit',England's South East,and the collapse of Thateherism显示文摘 | | 1995 | Environment and Planning A1995，27，： | 1 |
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