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| 1 | Overall rate, location, and predictive factors for positive surgical margins after robot-assisted laparoscopic radical prostatectomy for high-risk prostate cancer显示文摘我们与高风险的前列腺癌症在 271 个病人报导全面的率,地点和积极外科的边缘(PSM ) 的预兆的因素。在 2008 年 4 月和 2011 年 10 月之间,我们有希望地从作为 D'Amico 分类的病人收集了数据高风险经历了帮助机器人的 laparoscopic 激进分子前列腺切除术。PSM 的全面的率和地点被报导。逐步的逻辑回归模型被适合估计 PSM 的预兆的因素。PSM 的全面的率是 25.1%(271 个病人中的 68 个) 。这些 PSM,(68 中的 26 个)38.2% 是 posterolateral (PL ) , 26.5%(68 中的 18 个) multifocal, 16.2%(68 中的 11 个) 在顶, 14.7%(68 中的 10 个) 在膀胱颈,并且 4.4%(3/68 ) 在另外的地点。有病理学的阶段 pT2 的病人的 PSM 率是 8.6%(140 中的 12 个) , 26.6%(64 中的 17 个) pT3a, 53.3%(32/60 ) pT4 的 pT3b,和 100%(7 中的 7 个) 。在包括 pre- , intra- ,和手术后的参数的一个逻辑回归模型,身体团索引(机会比率[或] :1.09;95% 信心间隔[CI ] :1.01-1.19, P= 0.029 ) ,病理学的舞台(pT3b 或更高对 pT2;或:5.14;95% CI:1.92-13.78;P = 0.001 ) 并且肿瘤的百分比(或:46.71;95% CI:6.37-342.57;P < 0.001 ) 是为 PSM 的独立预兆的因素。在病人在的 PSM 的最普通的地点高风险是 PL 方面,它反映报导肿瘤攻击性。PSM 的唯一的重要预兆的因素是病理学的结果,例如在标本和病理学的舞台的肿瘤的百分比。 | Sung Gu Kang Oscar Schatloff Abdul Muhsin Haidar Srinivas Samavedi Kenneth J Palmer Jun Cheon Vipul R Patel | 2016 | Asian Journal of Andrology2016，18，1： | 9 |
| 2 | Femtojoule electro-optic modulation using a silicon– organic hybrid device显示文摘Energy-efficient electro-optic modulators are at the heart of short-reach optical interconnects,and silicon photonics is considered the leading technology for realizing such devices.However,the performance of all-silicon devices is limited by intrinsic material properties.In particular,the absence of linear electro-optic effects in silicon renders the integration of energy-efficient photonic–electronic interfaces challenging.Silicon–organic hybrid(SOH)integration can overcome these limitations by combining nanophotonic silicon waveguides with organic cladding materials,thereby offering the prospect of designing optical properties by molecular engineering.In this paper,we demonstrate an SOH Mach–Zehnder modulator with unprecedented efficiency:the 1-mm-long device consumes only 0.7 fJ bit^(-1) to generate a 12.5 Gbit s^(-1) data stream with a bit-error ratio below the threshold for hard-decision forward-error correction.This power consumption represents the lowest value demonstrated for a non-resonant Mach–Zehnder modulator in any material system.It is enabled by a novel class of organic electro-optic materials that are designed for high chromophore density and enhanced molecular orientation.The device features an electro-optic coefficient of r33<180 pm V^(-1) and can be operated at data rates of up to 40 Gbit s^(-1). | Sebastian Koeber Robert Palmer Matthias Lauermann Wolfgang Heni Delwin L Elder Dietmar Korn Markus Woessner Luca Alloatti Swen Koenig Philipp C Schindler Hui Yu Wim Bogaerts Larry R Dalton Wolfgang Freude Juerg Leuthold Christian Koos | 2015 | Light(Science & Applications)2015，4，1： | 4 |
| 3 | The ECMWF ensemble prediction system:methodology and validation显示文摘 | Molteni F Buizza R Palmer T N | 1996 | Q J R Meteorol Soc1996，122，529： | 2 |
| 4 | Changes in efficiency and resource utilization after increasing experience with double balloon enteroscopy显示文摘AIM:To investigate changes in efficiency and resource utilization as a single endoscopist's experience increased with each subsequent 100 double balloon enteroscopy(DBE) procedures.METHODS:We reviewed consecutive DBE procedures performed by a single endoscopist at our center over 4 years.DBE was employed when the clinician deemed the procedure was needed for disease management.The approach(oral,anal or both) was chosen based on suspected location of the target lesion.All DBE was performed in a standard endoscopy room with a portable fluoroscopy unit.Fluoroscopy was used to aid in shortening the small intestine and reducing bowel loops.For oral DBE,measurements were taken from the incisors.For anal DBE,measurements were taken from the anal verge.Enteroscopy continued until the target lesion was reached,until the entire small intestine was examined,or until no further progress was deemed possible.The length of small intestine examined(cm),procedure duration(min),and fluoroscopy time(s) were analyzed for sequential groups of 100 DBE.Sub-groups of diagnostic and therapeutic procedures were analyzed using multivariable linear regression.RESULTS:802 consecutive DBE procedures were analyzed.For oral DBE,median [interquartile range(IQR)] length of small bowel examined was 230.8 cm(range:210-248 cm) and for anal DBE was 143.5 cm(range:100-180 cm).No significant increase in length examined was noted for either the oral or anal approach with advancing position in series.In terms of duration of procedure,the median(IQR) for oral DBE was 86 min(range:71-105 min) and for anal DBE was 81.3 min(range:67-105 min).When comparing by the position in series,there was a significant(P value < 0.001) decrease in procedure duration for both upper and lower procedures with increasing experience.Median(IQR) time of exposure to fluoroscopy for oral DBE was 190 s(114-275) compared to anal DBE which was 196.4 s(312-128).This represented a significant(P value < 0.001) decrease in the amount of fluoroscopy used with increasing position in series.For both oral and anal DBE,fluoroscopy time was reduced by greater than 50% over the course of 802 total procedures performed.Sub-group analysis was conducted on therapeutic and diagnostic groups.Out of 802 procedures,a total of 434 were considered therapeutic.Argon plasma coagulation was by far the most common therapeutic intervention performed.There was no evidence of a difference in length examined or fluoroscopy exposure among oral DBE for diagnostic and therapeutic procedures,P = 0.91 and P = 0.32 respectively.The median(IQR) for length was 235 cm(range:178-280 cm) for diagnostic vs 230 cm(range:180-275 cm) for therapeutic procedures;additionally,fluoroscopy time median(IQR) was 180 s(range:110-295 s) and 162 s(range:102-263 s) for no intervention and intervention.However,there was a significant difference in procedure duration among oral DBE(P < 0.001).The median(IQR) was 80 min(range:60-97 min) and 94 min(range:77-110 min) for diagnostic and therapeutic interventions respectively.CONCLUSION:For a single endoscopist,increased DBE experience with number of performed procedures is associated with increased efficiency and decreased resource utilization. | Neal C Patel William C Palmer Kanwar R Gill David Cangemi Nancy Diehl Mark E Stark | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，3： | 2 |
| 5 | Stochastic representation of model uncertainties in the ECMWF EPS显示文摘 | Buizza R Miller M Palmer T N | 1999 | Q J R Meteorol Soc1999，125，560： | 2 |
| 6 | Vascular niche for adult hippocampal neurogenesis显示文摘 | Palmer T D Willhoite A R Gage F H | 2000 | J Comp Neurol2000，425，4： | 1 |
| 7 | Chloroplast DNA systematics:A review of methods and data analysis显示文摘 | OLMSTEAD R G PALMER J D | 1994 | American Journal of Botany1994，81，9： | 1 |
| 8 | Collision detection for animation using sphere-trees显示文摘 | Palmer L J Grimsdale R L | 1995 | Computer Graphics Forum1995，14，2： | 1 |
| 9 | Simulation and optimization of diode and insulated gate bipolar transistor interaction in a chopper cell using Matlab and Simulink 显示文摘 | Bryant A T Palmer P R | 2007 | IEEE Transactions on Industry Applications2007，43，： | 1 |
| 10 | Online social capital : Understanding e-impulse buying in practice 显示文摘 | De Kervenoael Aykac R Palmer M | 2009 | Journal of Retailing and Consumer Services2009，16，4： | 1 |
| 11 | Collision Detection for AnimationUsing Sphere-trees显示文摘 | Palmer I J Grimsdale R L | 1995 | Computer Graphics Forum1995，14，2： | 1 |
| 12 | An analysis of high-power IGBT switching under cascadeactive voltage control 显示文摘 | WANG Y PALMER P R BRYANT A T | 2009 | IEEE Transactions on In- dustry Applications2009，45，2： | 1 |
| 13 | Generalized cognitive impairments,ability to perform everyday tasks,and level of independence in community living situations of older patients with psychosis显示文摘 | Twamley E W Doshi R R Nayak G V Palmer B W | 2002 | The American Journal of Psychiatry2002，159，12： | 1 |
| 14 | A comparison of three methods of extracting resonance information from predictor-coefficient coded speech显示文摘 | CHRISTENSEN R L SREONG W J PALMER E P | 1976 | IEEE Transactions on ASSP1976，24，1： | 1 |
| 15 | Relative genetic contribution among ancestral lines to Noah American soybean cultivars显示文摘 | Delannay X Rodgers D M Palmer R G | 1983 | Crop Science1983，23，： | 1 |
| 16 | The relative significance of factors influencing and/or associated with beef tenderness 显示文摘 | Alsmeyer R H Palmer A Z Koger M | 1959 | Processing Meat Industry Research Conference1959，11，： | 1 |
| 17 | Sr isotope composition of sea water over the past 75 Myr 显示文摘 | Palmer M R Elderfield H | 1985 | Nature1985，314，： | 1 |
| 18 | Deferoxamine posttreatment reduces ischemic brain injury in neonatal rats 显示文摘 | Palmer C Roberts R L Bero C | 1994 | Stroke1994，25，5： | 1 |
| 19 | The strontium isotope budget of the modem ocean 显示文摘 | Palmer M R Edmond J M | 1989 | Earth Planet Sci Lett1989，92，： | 1 |
| 20 | Sintering of passivated gold nanoparticles under the electron beam 显示文摘 | Chen Y Palmer R E Wilcoxon J P | 2006 | Langmuir2006，22，： | 1 |
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