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| 1 | 射血分数正常心力衰竭的患病率和临床结局的变化趋势显示文摘Background: The prevalence of heart failure with preserved ejection fraction may be changing as a result of changes in population demographics and in the prevalence and treatment of risk factors for heart failure. Changes in the prevalence of heart failure with preserved ejection fraction may contribute to changes in the natural history of heart failure. We performed a study to define secular trends in the prevalence of heart failure with preserved ejection fraction among patients at a single institution over a 15-year period. Methods: We studied all consecutive patients hospitalized with decompensated heart failure at Mayo Clinic Hospitals in Olmsted County, Minnesota, from 1987 through 2001. We classified patients as having either preserved or reduced ejection fraction. The patients were also classified as community patients(Olmsted County residents) or referral patients. Secular trends in the type of heart failure, associated cardiovascular disease, and survival were defined. Results: A total of 6076 patients with heart failure were discharged over the 15-year period; data on ejection fraction were available for 4596 of these patients(76 percent). Of these, 53 percent had a reduced ejection fraction and 47 percent had a preserved ejection fraction. The proportion of patients with the diagnosis of heart failure with preserved ejection fraction increased over time and was significantly higher among community patients than among referral patients(55 percent vs. 45 percent). The prevalence rates of hypertension, atrial fibrillation, and diabetes among patients with heart failure increased significantly over time. Survival was slightly better among patients with preserved ejection fraction(adjusted hazard ratio for death, 0.96; P=0.01). Survival improved over time for those with reduced ejection fraction but not for those with preserved ejection fraction. Conclusions: The prevalence of heart failure with preserved ejection fraction increased over a 15-year period, while the rate of death from this disorder remained unchanged. These trends underscore the importance of this growing public health problem. | Owan T.E. Hodge D.O. Herges R.M. M.M. Redfield 马超 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，，12： | 11 |
| 2 | Trends inprevalence and outcome of heart failure with preserved ejectionfraction显示文摘 | OWAN TE HODGE DO HERGES RM | 2006 | N Engl J Med2006，355，26： | 1 |
| 3 | Trends in prevalence and outcome of heart failure with preserved ejection fraction显示文摘 | OWAN T E HODGE D O HERGES R M | 2006 | N Engl J Med2006，355，： | 1 |
| 4 | Epidemiology of diastolid heart failure 显示文摘 | Owan TE Redfield MM | 2005 | Prog Cardiovasc Dis2005，47，5： | 1 |
| 5 | Trends in preva- lence and outcome of heart failure with preserved ejection fraction显示文摘 | Owan TE Hodge DO Herges RM | 2006 | N Engl J Med2006，355，3： | 1 |
| 6 | Trends in prevalence and outcome of heart failure with preserved ejection fraction显示文摘 | Owan TE Hodge DO Herges RM | 2006 | N Engl J Med2006，355，3： | 1 |
| 7 | Trends in prevalence and outcome of Heart failure with preserved ejection fraction显示文摘 | Owan TE Hodge DO Herges RM et a1 | 2006 | New Engl J Med2006，355，3： | 1 |
| 8 | Mechanotransduction in bone: osteoblasts are more responsive to fluid forces than mechanical strain显示文摘 | Owan I Burr DB Turner CH | 1997 | Am J Physiol Cell Physiol1997，273，3： | 1 |
| 9 | Favorable changes in cardiac geometry and function following gastric bypass surgery:2-year follow-up in the Utah obesity study显示文摘 | Owan T Avelar E Morley K | 2011 | J Am Coil Cardiol2011，57，6： | 1 |
| 10 | Trends in prevalence and outcome of heart failure with preserved ejection fraction 显示文摘 | Owan TE Hodge DO Herges RM | 2006 | N Engl J Med2006，355，3： | 1 |
| 11 | Trends in prevalence and outcome of heart failure with preserved ejection fraction 显示文摘 | Owan TE Hodge DO Herges RM | 2006 | N Engl J Med2006，355，3： | 1 |
| 12 | Trends in prevalence and outcome of heart failure with preserved ejection fraction 显示文摘 | Owan TE Hodge DO Herges RM | 2006 | N Engl J Med2006，355，3： | 1 |
| 13 | Trends in prevalence and outcome of heart failure with preserved ejection fraction显示文摘 | Owan T E Hodge D O Herges R M | 2006 | N Engl J Med2006，355，3： | 1 |
| 14 | Mechanotransduction in bone: role of strain rate显示文摘 | Turner CH Owan I Takano Y | 1995 | Am J Physiol1995，269，31： | 1 |
| 15 | Trends in prevalance and outcome of heart failure with preserved ejection fraction显示文摘 | Owan TE Hodge DO Herges RM | 2006 | N Engl J Med2006，355，： | 1 |
| 16 | Trends in preva- lence and outcome of heart ailure with preserved ejection fraction 显示文摘 | Owan TE Hodge DO Herges RM | 2006 | N Engl J Med2006，355，3： | 1 |
| 17 | Fine patterning of transparent,conductive SnO2 thin films by UV-irradiation显示文摘 | Tomochika Owan Junichi Morinaga | 2000 | J Sol Gel Sci Technol2000，19，13： | 1 |
| 18 | Trends in prevalence and outcome of heart failure with preserved ejection fraction 显示文摘 | OWAN T E HODGE D O HERGES R M | 2006 | N Engl J Med2006，355，3： | 1 |
| 19 | Trends in prevalence and outcome of heart failure with preserved ejection fraction 显示文摘 | Owan TE Hedge DO Herges RM | 2006 | N EnglJ Med2006，355，3： | 1 |
| 20 | Trends in prevalence andoutcome of heart failure with preserved ejection fraction 显示文摘 | Owan TE Hodge DO Herges RM | 2006 | NEngl J Med2006，355，3： | 1 |
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